Showing entry for Chloride intracellular channel protein 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT003905
Protein NameChloride intracellular channel protein 1
Uniport IdO00299
GeneCLIC1
Gene Id1192
DomainGST_N_2
Pfam PF13409  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006821 chloride transport
Biological Process GO:0070527 platelet aggregation
Biological Process GO:0045669 positive regulation of osteoblast differentiation
Biological Process GO:0051726 regulation of cell cycle
Biological Process GO:0034765 regulation of ion transmembrane transport
Biological Process GO:0051881 regulation of mitochondrial membrane potential
Biological Process GO:0007165 signal transduction
molecular function GO:0045296 cadherin binding
molecular function GO:0005254 chloride channel activity
molecular function GO:0005244 voltage-gated ion channel activity
cellular component GO:0072562 blood microparticle
cellular component GO:0005903 brush border
cellular component GO:0034707 chloride channel complex
cellular component GO:0005737 cytoplasm
cellular component GO:0070062 extracellular exosome
cellular component GO:0005615 extracellular space
cellular component GO:0016020 membrane
cellular component GO:0005739 mitochondrion
cellular component GO:0005635 nuclear envelope
cellular component GO:0031965 nuclear membrane
cellular component GO:0005634 nucleus
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0005886 plasma membrane
cellular component GO:0031982 vesicle
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004997 BXGD000300 Benign Ovarian Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007129 BXGD000439 Merkel cell carcinoma Neoplasms; Infections
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0008350 BXGD000531 Cholelithiasis Digestive System Diseases
C0008497 BXGD000549 Choriocarcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0022548 BXGD001551 Keloid Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024232 BXGD001751 Lymphatic Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0086743 BXGD003308 Osteoarthrosis Deformans Musculoskeletal Diseases
C0153452 BXGD003647 Malignant neoplasm of gallbladder Digestive System Diseases; Neoplasms
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0200665 BXGD004045 Platelet mean volume determination (procedure)
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0235782 BXGD004769 Gallbladder Carcinoma Digestive System Diseases; Neoplasms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0278701 BXGD006566 Gastric Adenocarcinoma Digestive System Diseases; Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0812413 BXGD010847 Malignant Pleural Mesothelioma Neoplasms; Respiratory Tract Diseases
C0856169 BXGD011096 Endothelial dysfunction
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0947622 BXGD011493 Cholecystolithiasis Digestive System Diseases
C0947751 BXGD011494 Vascular inflammations Cardiovascular Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1257931 BXGD011815 Mammary Neoplasms, Human Neoplasms; Skin and Connective Tissue Diseases
C1261473 BXGD011855 Sarcoma Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C3163918 BXGD018520 Tumor thrombus Cardiovascular Diseases
C4505456 BXGD022964 HIV Coinfection Infections; Immune System Diseases
C4525297 BXGD023131 Stage 0 Gallbladder Cancer AJCC v8
C4525300 BXGD023132 Stage IIA Gallbladder Cancer AJCC v8
C4525301 BXGD023133 Stage IIB Gallbladder Cancer AJCC v8
C4525302 BXGD023134 Stage III Gallbladder Cancer AJCC v8
C4525305 BXGD023135 Stage IV Gallbladder Cancer AJCC v8
C4551686 BXGD023391 Malignant neoplasm of soft tissue Neoplasms
C4704874 BXGD023682 Mammary Carcinoma, Human Neoplasms; Skin and Connective Tissue Diseases
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000989 Glutathione 307.32
BXGC0002586 Calcium 40.08
BXGC0002616 Copper 63.55
BXGC0049447 acetate 59.01
BXGC0051100 dihydroartemisinin 284.16
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein