Showing entry for Lymphatic Metastasis


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD001751
Disease NameLymphatic Metastasis
Disease CUI IdC0024232
MeSH Codes C23   C04  
Disease Class NamePathological Conditions, Signs and Symptoms; Neoplasms
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00299 BXGT003905 Chloride intracellular channel protein 1 1192 reviewed Ion channel
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O14770 BXGT004095 Homeobox protein Meis2 4212 reviewed Enzyme
O14965 BXGT004117 Aurora kinase A 6790 reviewed Kinase
O15054 BXGT004121 Lysine-specific demethylase 6B 23135 reviewed Epigenetic regulator
O15075 BXGT004124 Serine/threonine-protein kinase DCLK1 9201 reviewed Kinase
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O15164 BXGT004133 Transcription intermediary factor 1-alpha 8805 reviewed
O15350 BXGT004154 Tumor protein p73 7161 reviewed Transcription factor
O43157 BXGT004572 Plexin-B1 5364 reviewed
O43915 BXGT004636 Vascular endothelial growth factor D 2277 reviewed Signaling
O60462 BXGT004876 Neuropilin-2 8828 reviewed
O60885 BXGT004906 Bromodomain-containing protein 4 23476 reviewed Epigenetic regulator
O75362 BXGT005114 Zinc finger protein 217 7764 reviewed
O75365 BXGT005115 Protein tyrosine phosphatase type IVA 3 11156 reviewed
O94925 BXGT005342 Glutaminase kidney isoform, mitochondrial 2744 reviewed Enzyme
O95150 BXGT005351 Tumor necrosis factor ligand superfamily member 15 9966 reviewed Signaling
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00749 BXGT005641 Urokinase-type plasminogen activator 5328 reviewed Enzyme
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01574 BXGT005768 Interferon beta 3456 reviewed
P02511 BXGT005885 Alpha-crystallin B chain 1410 reviewed
P02750 BXGT005942 Leucine-rich alpha-2-glycoprotein 116844 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04083 BXGT006147 Annexin A1 301 reviewed
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04275 BXGT006180 von Willebrand factor 7450 reviewed Enzyme modulator
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04731 BXGT006251 Metallothionein-1A 4489 reviewed
P04792 BXGT006264 Heat shock protein beta-1 3315 reviewed
P04818 BXGT006269 Thymidylate synthase 7298 reviewed Enzyme
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05161 BXGT006331 Ubiquitin-like protein ISG15 9636 reviewed Nucleic acid binding
P05230 BXGT006344 Fibroblast growth factor 1 2246 reviewed Signaling
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P05556 BXGT006368 Integrin beta-1 3688 reviewed Receptor
P06401 BXGT006436 Progesterone receptor 5241 reviewed Nuclear receptor
P06702 BXGT006476 Protein S100-A9 6280 reviewed Calcium-binding protein
P06730 BXGT006487 Eukaryotic translation initiation factor 4E 1977 reviewed Nucleic acid binding
P06731 BXGT006488 Carcinoembryonic antigen-related cell adhesion molecule 5 1048 reviewed
P07099 BXGT006546 Epoxide hydrolase 1 2052 reviewed
P07858 BXGT006689 Cathepsin B 1508 reviewed Enzyme
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08151 BXGT006731 Zinc finger protein GLI1 2735 reviewed
P08238 BXGT006753 Heat shock protein HSP 90-beta 3326 reviewed Chaperone
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08254 BXGT006758 Stromelysin-1 4314 reviewed Enzyme
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P08670 BXGT006810 Vimentin 7431 reviewed
P08758 BXGT006821 Annexin A5 308 reviewed
P09237 BXGT006874 Matrilysin 4316 reviewed Enzyme
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P12429 BXGT007814 Annexin A3 306 reviewed
P12830 BXGT007852 Cadherin-1 999 reviewed
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13569 BXGT007923 Cystic fibrosis transmembrane conductance regulator 1080 reviewed Ion channel
P13674 BXGT007942 Prolyl 4-hydroxylase subunit alpha-1 5033 reviewed
P13726 BXGT007950 Tissue factor 2152 reviewed Receptor
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15311 BXGT008106 Ezrin 7430 reviewed Cellular structure
P15531 BXGT008136 Nucleoside diphosphate kinase A 4830 reviewed Kinase
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15941 BXGT008176 Mucin-1 4582 reviewed
P16070 BXGT008186 CD44 antigen 960 reviewed
P16220 BXGT008206 Cyclic AMP-responsive element-binding protein 1 1385 reviewed
P16473 BXGT008234 Thyrotropin receptor 7253 reviewed G-protein coupled receptor
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P18146 BXGT008384 Early growth response protein 1 1958 reviewed Nucleic acid binding
P18669 BXGT008419 Phosphoglycerate mutase 1 5223 reviewed
P18827 BXGT008427 Syndecan-1 6382 reviewed Extracellular structure
P21579 BXGT008665 Synaptotagmin-1 6857 reviewed Transporter
P22001 BXGT008716 Potassium voltage-gated channel subfamily A member 3 3738 reviewed Ion channel
P22626 BXGT008787 Heterogeneous nuclear ribonucleoproteins A2/B1 3181 reviewed
P23458 BXGT008868 Tyrosine-protein kinase JAK1 3716 reviewed Kinase
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P25025 BXGT009006 C-X-C chemokine receptor type 2 3579 reviewed G-protein coupled receptor
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P29074 BXGT009313 Tyrosine-protein phosphatase non-receptor type 4 5775 reviewed
P29317 BXGT009331 Ephrin type-A receptor 2 1969 reviewed Kinase
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P31947 BXGT009589 14-3-3 protein sigma 2810 reviewed Chaperone
P32320 BXGT009622 Cytidine deaminase 978 reviewed Enzyme
P34903 BXGT009769 Gamma-aminobutyric acid receptor subunit alpha-3 2556 reviewed Ion channel
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35414 BXGT009829 Apelin receptor 187 reviewed G-protein coupled receptor
P35442 BXGT009832 Thrombospondin-2 7058 reviewed
P35613 BXGT009856 Basigin 682 reviewed
P35916 BXGT009881 Vascular endothelial growth factor receptor 3 2324 reviewed Kinase
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P36551 BXGT009927 Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial 1371 reviewed Enzyme
P39748 BXGT010134 Flap endonuclease 1 2237 reviewed Enzyme
P40692 BXGT010195 DNA mismatch repair protein Mlh1 4292 reviewed Nucleic acid binding
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41161 BXGT010229 ETS translocation variant 5 2119 reviewed Transcription factor
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P42702 BXGT010335 Leukemia inhibitory factor receptor 3977 reviewed Signaling
P43235 BXGT010368 Cathepsin K 1513 reviewed Enzyme
P43246 BXGT010371 DNA mismatch repair protein Msh2 4436 reviewed Nucleic acid binding
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49023 BXGT010672 Paxillin 5829 reviewed Cellular structure
P49327 BXGT010694 Fatty acid synthase 2194 reviewed Enzyme
P49767 BXGT010739 Vascular endothelial growth factor C 7424 reviewed Signaling
P49789 BXGT010742 Bis(5'-adenosyl)-triphosphatase 2272 reviewed
P50281 BXGT010788 Matrix metalloproteinase-14 4323 reviewed Enzyme
P51532 BXGT010852 Transcription activator BRG1 6597 reviewed Epigenetic regulator
P51681 BXGT010878 C-C chemokine receptor type 5 1234 reviewed G-protein coupled receptor
P51790 BXGT010890 H(+)/Cl(-) exchange transporter 3 1182 reviewed Ion channel
P51946 BXGT010907 Cyclin-H 902 reviewed Enzyme modulator
P53350 BXGT010984 Serine/threonine-protein kinase PLK1 5347 reviewed Kinase
P54278 BXGT011038 Mismatch repair endonuclease PMS2 5395 reviewed Nucleic acid binding
P56945 BXGT011206 Breast cancer anti-estrogen resistance protein 1 9564 reviewed
P57735 BXGT011214 Ras-related protein Rab-25 57111 reviewed
P60174 BXGT011294 Triosephosphate isomerase 7167 reviewed Enzyme
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P60953 BXGT011342 Cell division control protein 42 homolog 998 reviewed Enzyme modulator
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P63000 BXGT011481 Ras-related C3 botulinum toxin substrate 1 5879 reviewed Enzyme modulator
P63316 BXGT011517 Troponin C, slow skeletal and cardiac muscles 7134 reviewed Calcium-binding protein
P78380 BXGT011841 Oxidized low-density lipoprotein receptor 1 4973 reviewed
P98170 BXGT012231 E3 ubiquitin-protein ligase XIAP 331 reviewed Enzyme modulator
Q04206 BXGT012754 Transcription factor p65 5970 reviewed Transcription factor
Q04609 BXGT012768 Glutamate carboxypeptidase 2 2346 reviewed Enzyme
Q04912 BXGT012790 Macrophage-stimulating protein receptor 4486 reviewed Kinase
Q05513 BXGT012820 Protein kinase C zeta type 5590 reviewed Kinase
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q09472 BXGT013038 Histone acetyltransferase p300 2033 reviewed
Q10589 BXGT013203 Bone marrow stromal antigen 2 684 reviewed
Q13002 BXGT013303 Glutamate receptor ionotropic, kainate 2 2898 reviewed Ion channel
Q13009 BXGT013305 T-lymphoma invasion and metastasis-inducing protein 1 7074 reviewed
Q13233 BXGT013330 Mitogen-activated protein kinase kinase kinase 1 4214 reviewed Kinase
Q13485 BXGT013363 Mothers against decapentaplegic homolog 4 4089 reviewed Transcription factor
Q13546 BXGT013372 Receptor-interacting serine/threonine-protein kinase 1 8737 reviewed Kinase
Q14002 BXGT013433 Carcinoembryonic antigen-related cell adhesion molecule 7 1087 reviewed
Q14315 BXGT013460 Filamin-C 2318 reviewed
Q15116 BXGT013539 Programmed cell death protein 1 5133 reviewed
Q15788 BXGT013598 Nuclear receptor coactivator 1 8648 reviewed Kinase
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q6ZN17 BXGT016631 Protein lin-28 homolog B 389421 reviewed
Q86V24 BXGT017615 Adiponectin receptor protein 2 79602 reviewed Receptor
Q8TDQ0 BXGT018810 Hepatitis A virus cellular receptor 2 84868 reviewed
Q8TEK3 BXGT018822 Histone-lysine N-methyltransferase, H3 lysine-79 specific 84444 reviewed Epigenetic regulator
Q92736 BXGT019367 Ryanodine receptor 2 6262 reviewed Ion channel
Q92835 BXGT019382 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 3635 reviewed
Q92854 BXGT019385 Semaphorin-4D 10507 reviewed Signaling
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96QV1 BXGT019722 Hedgehog-interacting protein 64399 reviewed
Q99572 BXGT019935 P2X purinoceptor 7 5027 reviewed Ion channel
Q99836 BXGT019970 Myeloid differentiation primary response protein MyD88 4615 reviewed Enzyme modulator
Q9BUZ4 BXGT020139 TNF receptor-associated factor 4 9618 reviewed Signaling
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9H4A3 BXGT020473 Serine/threonine-protein kinase WNK1 65125 reviewed Kinase
Q9HAS3 BXGT020507 Solute carrier family 28 member 3 64078 reviewed Transporter
Q9HBE5 BXGT020518 Interleukin-21 receptor 50615 reviewed Receptor
Q9NPH5 BXGT021159 NADPH oxidase 4 50507 reviewed Enzyme
Q9NYA1 BXGT021254 Sphingosine kinase 1 8877 reviewed Kinase
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UBC3 BXGT021650 DNA (cytosine-5)-methyltransferase 3B 1789 reviewed
Q9ULW0 BXGT021766 Targeting protein for Xklp2 22974 reviewed Cellular structure
Q9UNL4 BXGT021790 Inhibitor of growth protein 4 51147 reviewed Nucleic acid binding
Q9UQ80 BXGT021806 Proliferation-associated protein 2G4 5036 reviewed
Q9Y251 BXGT022215 Heparanase 10855 reviewed Enzyme
Q92482 BXGT022676 Aquaporin-3 360 reviewed Ion channel
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
Q13330 BXGT023103 Metastasis-associated protein MTA1 9112 reviewed Nucleic acid binding
Q01543 BXGT023137 Friend leukemia integration 1 transcription factor 2313 reviewed Transcription factor
Q01955 BXGT023255 Collagen alpha-3(IV) chain 1285 reviewed
Q99958 BXGT023732 Forkhead box protein C2 2303 reviewed Transcription factor
P40198 BXGT023750 Carcinoembryonic antigen-related cell adhesion molecule 3 1084 reviewed
P20138 BXGT023857 Myeloid cell surface antigen CD33 945 reviewed Receptor
Q96QC4 BXGT023878 MHC class I polypeptide-related sequence A 100507436 unreviewed
Q13007 BXGT023883 Interleukin-24 11009 reviewed
Q9BQQ3 BXGT024065 Golgi reassembly-stacking protein 1 64689 reviewed
O60232 BXGT024169 Protein ZNRD2 10534 reviewed
Q12888 BXGT024878 TP53-binding protein 1 7158 reviewed Epigenetic regulator
Q7L8A9 BXGT025010 Tubulinyl-Tyr carboxypeptidase 1 22846 reviewed
P98082 BXGT025047 Disabled homolog 2 1601 reviewed Signaling
Q99435 BXGT025240 Protein kinase C-binding protein NELL2 4753 reviewed Calcium-binding protein
Q9BY76 BXGT025687 Angiopoietin-related protein 4 51129 reviewed Signaling
Q9BQ69 BXGT026098 ADP-ribose glycohydrolase MACROD1 28992 reviewed
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease