Showing entry for Asparagine--tRNA ligase, cytoplasmic


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004624
Protein NameAsparagine--tRNA ligase, cytoplasmic
Uniport IdO43776
GeneNARS1
Gene Id4677
DomaintRNA-synt_2; tRNA_anti-codon
Pfam PF00152   PF01336  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.2 Translation hsa00970 Aminoacyl-tRNA biosynthesis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006421 asparaginyl-tRNA aminoacylation
Biological Process GO:0016477 cell migration
Biological Process GO:0006418 tRNA aminoacylation for protein translation
molecular function GO:0004816 asparagine-tRNA ligase activity
molecular function GO:0005524 ATP binding
molecular function GO:0031728 CCR3 chemokine receptor binding
molecular function GO:0003676 nucleic acid binding
molecular function GO:0046983 protein dimerization activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
Reactome
Pathway Id Pathway Name
R-HSA-379716 Cytosolic tRNA aminoacylation
R-HSA-379724 tRNA Aminoacylation
R-HSA-392499 Metabolism of proteins
R-HSA-72766 Translation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000833 BXGD000014 Abscess Pathological Conditions, Signs and Symptoms; Infections
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0004604 BXGD000278 Back Pain Pathological Conditions, Signs and Symptoms
C0006625 BXGD000401 Cachexia Pathological Conditions, Signs and Symptoms
C0007113 BXGD000430 Rectal Carcinoma Digestive System Diseases; Neoplasms
C0007859 BXGD000494 Neck Pain Pathological Conditions, Signs and Symptoms
C0008031 BXGD000511 Chest Pain Pathological Conditions, Signs and Symptoms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010200 BXGD000653 Coughing Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0013884 BXGD000864 Filarial Elephantiases Infections; Hemic and Lymphatic Diseases
C0015468 BXGD000995 Facial Pain Pathological Conditions, Signs and Symptoms
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0016204 BXGD001051 Flatulence Pathological Conditions, Signs and Symptoms
C0018681 BXGD001214 Headache Pathological Conditions, Signs and Symptoms
C0023222 BXGD001620 Pain in lower limb
C0025312 BXGD001861 Meningomyelocele Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0026838 BXGD001938 Muscle Spasticity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0028259 BXGD002073 Nodule
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030201 BXGD002194 Pain, Postoperative Pathological Conditions, Signs and Symptoms
C0038362 BXGD002749 Stomatitis Stomatognathic Diseases
C0038436 BXGD002755 Post-Traumatic Stress Disorder Mental Disorders
C0162429 BXGD003942 Malnutrition Nutritional and Metabolic Diseases
C0206062 BXGD004148 Lung Diseases, Interstitial Respiratory Tract Diseases
C0239377 BXGD004980 Arm Pain Pathological Conditions, Signs and Symptoms
C0278139 BXGD006499 Moderate pain Pathological Conditions, Signs and Symptoms
C0278498 BXGD006521 Malignant neoplasm of stomach stage IV
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0522187 BXGD009195 Tocophobia Mental Disorders
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0563625 BXGD009484 Agnosia for Pain Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0700613 BXGD009896 Anxiety state Mental Disorders; Behavior and Behavior Mechanisms
C1279420 BXGD012122 Anxiety neurosis (finding) Mental Disorders
C1568868 BXGD013423 Oral Mucositis Stomatognathic Diseases
C3873567 BXGD019863 Peripheral neuropathy due to and following chemotherapy Nervous System Diseases
C4285782 BXGD022453 Kinesiophobia
C4727070 BXGD023851 Advanced Carcinoma
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0000458 L-Asparagine 132.12
BXGC0003705 Chloride 35.45
BXGC0038991 Selenomethionine 197
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein