adisease

Showing entry for Nodule

General Disease Information
BXGD Id	BXGD002073
Disease Name	Nodule
Disease CUI Id	C0028259
MeSH Codes
Disease Class Name
Semantic Type	Acquired Abnormality
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O14788	BXGT004100	Tumor necrosis factor ligand superfamily member 11	8600	reviewed	Signaling
O14965	BXGT004117	Aurora kinase A	6790	reviewed	Kinase
O43776	BXGT004624	Asparagine--tRNA ligase, cytoplasmic	4677	reviewed	Enzyme
O43791	BXGT004626	Speckle-type POZ protein	8405	reviewed
O60218	BXGT004858	Aldo-keto reductase family 1 member B10	57016	reviewed	Enzyme
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O75030	BXGT005096	Microphthalmia-associated transcription factor	4286	reviewed
O95954	BXGT005408	Formimidoyltransferase-cyclodeaminase	10841	reviewed	Enzyme
P00488	BXGT005552	Coagulation factor XIII A chain	2162	reviewed	Enzyme
P00505	BXGT005560	Aspartate aminotransferase, mitochondrial	2806	reviewed
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00734	BXGT005630	Prothrombin	2147	reviewed	Enzyme
P00747	BXGT005639	Plasminogen	5340	reviewed	Enzyme
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P00915	BXGT005689	Carbonic anhydrase 1	759	reviewed
P01111	BXGT005731	GTPase NRas	4893	reviewed	Enzyme modulator
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01270	BXGT005746	Parathyroid hormone	5741	reviewed
P01275	BXGT005747	Glucagon	2641	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P02452	BXGT005878	Collagen alpha-1(I) chain	1277	reviewed
P02647	BXGT005908	Apolipoprotein A-I	335	reviewed
P02751	BXGT005943	Fibronectin	2335	reviewed	Signaling
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P02818	BXGT005969	Osteocalcin	632	reviewed
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05023	BXGT006294	Sodium/potassium-transporting ATPase subunit alpha-1	476	reviewed	Transporter
P05107	BXGT006316	Integrin beta-2	3689	reviewed	Receptor
P05186	BXGT006338	Alkaline phosphatase, tissue-nonspecific isozyme	249	reviewed	Enzyme
P05187	BXGT006339	Alkaline phosphatase, placental type	250	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06401	BXGT006436	Progesterone receptor	5241	reviewed	Nuclear receptor
P06731	BXGT006488	Carcinoembryonic antigen-related cell adhesion molecule 5	1048	reviewed
P06744	BXGT006494	Glucose-6-phosphate isomerase	2821	reviewed	Enzyme
P07101	BXGT006547	Tyrosine 3-monooxygenase	7054	reviewed
P07202	BXGT006565	Thyroid peroxidase	7173	reviewed	Enzyme
P07225	BXGT006572	Vitamin K-dependent protein S	5627	reviewed
P07288	BXGT006591	Prostate-specific antigen	354	reviewed	Enzyme
P07339	BXGT006604	Cathepsin D	1509	reviewed	Enzyme
P07858	BXGT006689	Cathepsin B	1508	reviewed	Enzyme
P07949	BXGT006703	Proto-oncogene tyrosine-protein kinase receptor Ret	5979	reviewed	Kinase
P08236	BXGT006752	Beta-glucuronidase	2990	reviewed
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08254	BXGT006758	Stromelysin-1	4314	reviewed	Enzyme
P08473	BXGT006773	Neprilysin	4311	reviewed	Enzyme
P08670	BXGT006810	Vimentin	7431	reviewed
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10275	BXGT007552	Androgen receptor	367	reviewed	Nuclear receptor
P10323	BXGT007557	Acrosin	49	reviewed	Enzyme
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10599	BXGT007583	Thioredoxin	7295	reviewed
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P11166	BXGT007661	Solute carrier family 2, facilitated glucose transporter member 1	6513	reviewed	Transporter
P11215	BXGT007672	Integrin alpha-M	3684	reviewed
P11308	BXGT007684	Transcriptional regulator ERG	2078	reviewed	Transcription factor
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P11511	BXGT007717	Aromatase	1588	reviewed	Enzyme
P11912	BXGT007758	B-cell antigen receptor complex-associated protein alpha chain	973	reviewed	Receptor
P12643	BXGT007830	Bone morphogenetic protein 2	650	reviewed	Signaling
P12830	BXGT007852	Cadherin-1	999	reviewed
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15289	BXGT008102	Arylsulfatase A	410	reviewed	Enzyme
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16070	BXGT008186	CD44 antigen	960	reviewed
P16278	BXGT008213	Beta-galactosidase	2720	reviewed	Enzyme
P16473	BXGT008234	Thyrotropin receptor	7253	reviewed	G-protein coupled receptor
P16930	BXGT008272	Fumarylacetoacetase	2184	reviewed
P17931	BXGT008356	Galectin-3	3958	reviewed	Signaling
P17936	BXGT008357	Insulin-like growth factor-binding protein 3	3486	reviewed	Enzyme modulator
P18846	BXGT008430	Cyclic AMP-dependent transcription factor ATF-1	466	reviewed
P18848	BXGT008432	Cyclic AMP-dependent transcription factor ATF-4	468	reviewed
P19099	BXGT008456	Cytochrome P450 11B2, mitochondrial	1585	reviewed
P19440	BXGT008481	Glutathione hydrolase 1 proenzyme	2678	reviewed	Enzyme
P21730	BXGT008687	C5a anaphylatoxin chemotactic receptor 1	728	reviewed	G-protein coupled receptor
P21802	BXGT008691	Fibroblast growth factor receptor 2	2263	reviewed	Kinase
P22004	BXGT008718	Bone morphogenetic protein 6	654	reviewed	Signaling
P23297	BXGT008848	Protein S100-A1	6271	reviewed	Calcium-binding protein
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P27708	BXGT009202	CAD protein	790	reviewed	Enzyme
P28300	BXGT009243	Protein-lysine 6-oxidase	4015	reviewed
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P28908	BXGT009302	Tumor necrosis factor receptor superfamily member 8	943	reviewed
P29323	BXGT009334	Ephrin type-B receptor 2	2048	reviewed	Kinase
P30530	BXGT009431	Tyrosine-protein kinase receptor UFO	558	reviewed	Kinase
P31947	BXGT009589	14-3-3 protein sigma	2810	reviewed	Chaperone
P32119	BXGT009600	Peroxiredoxin-2	7001	reviewed	Enzyme
P33527	BXGT009728	Multidrug resistance-associated protein 1	4363	reviewed	Transporter
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35590	BXGT009854	Tyrosine-protein kinase receptor Tie-1	7075	reviewed	Kinase
P35754	BXGT009863	Glutaredoxin-1	2745	reviewed
P41182	BXGT010231	B-cell lymphoma 6 protein	604	reviewed
P41597	BXGT010268	C-C chemokine receptor type 2	729230	reviewed
P43026	BXGT010351	Growth/differentiation factor 5	8200	reviewed	Signaling
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P48023	BXGT010604	Tumor necrosis factor ligand superfamily member 6	356	reviewed	Signaling
P48544	BXGT010641	G protein-activated inward rectifier potassium channel 4	3762	reviewed	Ion channel
P49019	BXGT010671	Hydroxycarboxylic acid receptor 3	8843	reviewed	G-protein coupled receptor
P49747	BXGT010732	Cartilage oligomeric matrix protein	1311	reviewed
P51955	BXGT010908	Serine/threonine-protein kinase Nek2	4751	reviewed	Kinase
P55786	BXGT011125	Puromycin-sensitive aminopeptidase	9520	reviewed	Enzyme
P58335	BXGT011233	Anthrax toxin receptor 2	118429	reviewed	Receptor
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P61160	BXGT011365	Actin-related protein 2	10097	reviewed	Cellular structure
P61964	BXGT011396	WD repeat-containing protein 5	11091	reviewed
P78504	BXGT011844	Protein jagged-1	182	reviewed
Q01668	BXGT012605	Voltage-dependent L-type calcium channel subunit alpha-1D	776	reviewed	Ion channel
Q04609	BXGT012768	Glutamate carboxypeptidase 2	2346	reviewed	Enzyme
Q13257	BXGT013333	Mitotic spindle assembly checkpoint protein MAD2A	4085	reviewed
Q13501	BXGT013365	Sequestosome-1	8878	reviewed
Q15582	BXGT013581	Transforming growth factor-beta-induced protein ig-h3	7045	reviewed	Signaling
Q15910	BXGT013612	Histone-lysine N-methyltransferase EZH2	2146	reviewed	Epigenetic regulator
Q68D85	BXGT016188	Natural cytotoxicity triggering receptor 3 ligand 1	374383	reviewed
Q7L266	BXGT016993	Isoaspartyl peptidase/L-asparaginase	80150	reviewed	Enzyme
Q92743	BXGT019368	Serine protease HTRA1	5654	reviewed	Enzyme
Q96AC1	BXGT019617	Fermitin family homolog 2	10979	reviewed
Q96E93	BXGT019645	Killer cell lectin-like receptor subfamily G member 1	10219	reviewed
Q9GZX6	BXGT020428	Interleukin-22	50616	reviewed
Q9H0A0	BXGT020434	RNA cytidine acetyltransferase	55226	reviewed
Q9UBK8	BXGT021655	Methionine synthase reductase	4552	reviewed
Q9UM73	BXGT021773	ALK tyrosine kinase receptor	238	reviewed	Kinase
Q9Y617	BXGT022314	Phosphoserine aminotransferase	29968	reviewed
Q9Y6R4	BXGT022340	Mitogen-activated protein kinase kinase kinase 4	4216	reviewed	Kinase
Q92911	BXGT022650	Sodium/iodide cotransporter	6528	reviewed	Transporter
P25054	BXGT022961	Adenomatous polyposis coli protein	324	reviewed
Q9UK05	BXGT023094	Growth/differentiation factor 2	2658	reviewed	Signaling
O14793	BXGT023280	Growth/differentiation factor 8	2660	reviewed	Signaling
Q9BVI0	BXGT023340	PHD finger protein 20	51230	reviewed
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
P00395	BXGT023596	Cytochrome c oxidase subunit 1	4512	reviewed	Enzyme
Q13635	BXGT024910	Protein patched homolog 1	5727	reviewed
Q9UKU9	BXGT025985	Angiopoietin-related protein 2	23452	reviewed	Signaling
P11836	BXGT025994	B-lymphocyte antigen CD20	931	reviewed	Receptor
P58215	BXGT026106	Lysyl oxidase homolog 3	84695	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}