Showing entry for Post-Traumatic Stress Disorder


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD002755
Disease NamePost-Traumatic Stress Disorder
Disease CUI IdC0038436
MeSH Codes F03  
Disease Class NameMental Disorders
Semantic TypeMental or Behavioral Dysfunction
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:150  
Disease Ontology Class Namedisease of mental health
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00141 BXGT003882 Serine/threonine-protein kinase Sgk1 6446 reviewed Kinase
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00519 BXGT003934 Fatty-acid amide hydrolase 1 2166 reviewed
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O14964 BXGT004116 Hepatocyte growth factor-regulated tyrosine kinase substrate 9146 reviewed
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O15350 BXGT004154 Tumor protein p73 7161 reviewed Transcription factor
O43612 BXGT004605 Orexin 3060 reviewed
O43776 BXGT004624 Asparagine--tRNA ligase, cytoplasmic 4677 reviewed Enzyme
O43897 BXGT004633 Tolloid-like protein 1 7092 reviewed
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O60741 BXGT004897 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 348980 reviewed
O75460 BXGT005127 Serine/threonine-protein kinase/endoribonuclease IRE1 2081 reviewed Kinase
O75628 BXGT005140 GTP-binding protein REM 1 28954 reviewed
O75751 BXGT005150 Solute carrier family 22 member 3 6581 reviewed Transporter
P00390 BXGT005526 Glutathione reductase, mitochondrial 2936 reviewed Enzyme
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00451 BXGT005545 Coagulation factor VIII 2157 reviewed Enzyme
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01303 BXGT005748 Pro-neuropeptide Y 4852 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P01909 BXGT005815 HLA class II histocompatibility antigen, DQ alpha 1 chain 3117 reviewed Immune response
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P01920 BXGT005817 HLA class II histocompatibility antigen, DQ beta 1 chain 3119 reviewed Immune response
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02774 BXGT005959 Vitamin D-binding protein 2638 reviewed Transporter
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P03915 BXGT006114 NADH-ubiquinone oxidoreductase chain 5 4540 reviewed Enzyme
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P04406 BXGT006207 Glyceraldehyde-3-phosphate dehydrogenase 2597 reviewed Enzyme
P04440 BXGT006216 HLA class II histocompatibility antigen, DP beta 1 chain 3115 reviewed Immune response
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04745 BXGT006255 Alpha-amylase 1 278 reviewed
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P05413 BXGT006355 Fatty acid-binding protein, heart 2170 reviewed
P06276 BXGT006430 Cholinesterase 590 reviewed
P06850 BXGT006511 Corticoliberin 1392 reviewed Signaling
P07101 BXGT006547 Tyrosine 3-monooxygenase 7054 reviewed
P07203 BXGT006566 Glutathione peroxidase 1 2876 reviewed Enzyme
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P08235 BXGT006751 Mineralocorticoid receptor 4306 reviewed Nuclear receptor
P08246 BXGT006756 Neutrophil elastase 1991 reviewed Enzyme
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P08908 BXGT006837 5-hydroxytryptamine receptor 1A 3350 reviewed G-protein coupled receptor
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09172 BXGT006865 Dopamine beta-hydroxylase 1621 reviewed
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P10144 BXGT007541 Granzyme B 3002 reviewed Enzyme
P10147 BXGT007543 C-C motif chemokine 3 6348 reviewed Signaling
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P11802 BXGT007750 Cyclin-dependent kinase 4 1019 reviewed Kinase
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13236 BXGT007891 C-C motif chemokine 4 6351 reviewed
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P14416 BXGT008011 D(2) dopamine receptor 1813 reviewed G-protein coupled receptor
P14616 BXGT008026 Insulin receptor-related protein 3645 reviewed Kinase
P15309 BXGT008105 Prostatic acid phosphatase 55 reviewed Enzyme
P15941 BXGT008176 Mucin-1 4582 reviewed
P16050 BXGT008184 Arachidonate 15-lipoxygenase 246 reviewed Enzyme
P16220 BXGT008206 Cyclic AMP-responsive element-binding protein 1 1385 reviewed
P16435 BXGT008226 NADPH--cytochrome P450 reductase 5447 reviewed
P17252 BXGT008294 Protein kinase C alpha type 5578 reviewed Kinase
P18054 BXGT008370 Arachidonate 12-lipoxygenase, 12S-type 239 reviewed Enzyme
P18089 BXGT008379 Alpha-2B adrenergic receptor 151 reviewed G-protein coupled receptor
P19320 BXGT008470 Vascular cell adhesion protein 1 7412 reviewed
P19438 BXGT008480 Tumor necrosis factor receptor superfamily member 1A 7132 reviewed
P19623 BXGT008503 Spermidine synthase 6723 reviewed Enzyme
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P19883 BXGT008528 Follistatin 10468 reviewed Enzyme modulator
P21397 BXGT008644 Amine oxidase [flavin-containing] A 4128 reviewed
P21554 BXGT008662 Cannabinoid receptor 1 1268 reviewed G-protein coupled receptor
P21728 BXGT008686 D(1A) dopamine receptor 1812 reviewed G-protein coupled receptor
P21917 BXGT008707 D(4) dopamine receptor 1815 reviewed G-protein coupled receptor
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P22304 BXGT008752 Iduronate 2-sulfatase 3423 reviewed
P22607 BXGT008784 Fibroblast growth factor receptor 3 2261 reviewed Kinase
P22681 BXGT008795 E3 ubiquitin-protein ligase CBL 867 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P25103 BXGT009020 Substance-P receptor 6869 reviewed G-protein coupled receptor
P25325 BXGT009038 3-mercaptopyruvate sulfurtransferase 4357 reviewed Enzyme
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P27797 BXGT009206 Calreticulin 811 reviewed Calcium-binding protein
P27815 BXGT009208 cAMP-specific 3',5'-cyclic phosphodiesterase 4A 5141 reviewed
P28223 BXGT009239 5-hydroxytryptamine receptor 2A 3356 reviewed G-protein coupled receptor
P28335 BXGT009255 5-hydroxytryptamine receptor 2C 3358 reviewed G-protein coupled receptor
P28472 BXGT009260 Gamma-aminobutyric acid receptor subunit beta-3 2562 reviewed Ion channel
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29074 BXGT009313 Tyrosine-protein phosphatase non-receptor type 4 5775 reviewed
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P29460 BXGT009348 Interleukin-12 subunit beta 3593 reviewed Signaling
P29475 BXGT009353 Nitric oxide synthase, brain 4842 reviewed
P30101 BXGT009402 Protein disulfide-isomerase A3 2923 reviewed
P30531 BXGT009432 Sodium- and chloride-dependent GABA transporter 1 6529 reviewed Transporter
P30532 BXGT009433 Neuronal acetylcholine receptor subunit alpha-5 1138 reviewed Ion channel
P30536 BXGT009435 Translocator protein 706 reviewed
P30559 BXGT009442 Oxytocin receptor 5021 reviewed G-protein coupled receptor
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 1143 reviewed Ion channel
P31213 BXGT009515 3-oxo-5-alpha-steroid 4-dehydrogenase 2 6716 reviewed Enzyme
P31645 BXGT009558 Sodium-dependent serotonin transporter 6532 reviewed Transporter
P34130 BXGT009752 Neurotrophin-4 4909 reviewed Signaling
P34949 BXGT009775 Mannose-6-phosphate isomerase 4351 reviewed Enzyme
P34998 BXGT009781 Corticotropin-releasing factor receptor 1 1394 reviewed
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35372 BXGT009823 Mu-type opioid receptor 4988 reviewed G-protein coupled receptor
P35398 BXGT009825 Nuclear receptor ROR-alpha 6095 reviewed Nuclear receptor
P35462 BXGT009835 D(3) dopamine receptor 1814 reviewed G-protein coupled receptor
P35916 BXGT009881 Vascular endothelial growth factor receptor 3 2324 reviewed Kinase
P37840 BXGT010015 Alpha-synuclein 6622 reviewed Transporter
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P39019 BXGT010082 40S ribosomal protein S19 6223 reviewed Nucleic acid binding
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P40933 BXGT010209 Interleukin-15 3600 reviewed
P41145 BXGT010225 Kappa-type opioid receptor 4986 reviewed G-protein coupled receptor
P41146 BXGT010226 Nociceptin receptor 4987 reviewed G-protein coupled receptor
P41222 BXGT010237 Prostaglandin-H2 D-isomerase 5730 reviewed Enzyme
P41594 BXGT010266 Metabotropic glutamate receptor 5 2915 reviewed G-protein coupled receptor
P43005 BXGT010349 Excitatory amino acid transporter 3 6505 reviewed Transporter
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 1137 reviewed Ion channel
P46098 BXGT010507 5-hydroxytryptamine receptor 3A 3359 reviewed Ion channel
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P48506 BXGT010635 Glutamate--cysteine ligase catalytic subunit 2729 reviewed Enzyme
P48637 BXGT010649 Glutathione synthetase 2937 reviewed Enzyme
P48775 BXGT010662 Tryptophan 2,3-dioxygenase 6999 reviewed Enzyme
P49903 BXGT010759 Selenide, water dikinase 1 22929 reviewed Enzyme
P51692 BXGT010885 Signal transducer and activator of transcription 5B 6777 reviewed Nucleic acid binding
P52788 BXGT010953 Spermine synthase 6611 reviewed
P55211 BXGT011111 Caspase-9 842 reviewed Enzyme
P56373 BXGT011164 P2X purinoceptor 3 5024 reviewed Ion channel
P56524 BXGT011176 Histone deacetylase 4 9759 reviewed Epigenetic regulator
P60568 BXGT011315 Interleukin-2 3558 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P60880 BXGT011335 Synaptosomal-associated protein 25 6616 reviewed Transporter
P60903 BXGT011339 Protein S100-A10 6281 reviewed Calcium-binding protein
P61626 BXGT011382 Lysozyme C 4069 reviewed
P62314 BXGT011420 Small nuclear ribonucleoprotein Sm D1 6632 reviewed Nucleic acid binding
P62753 BXGT011454 40S ribosomal protein S6 6194 reviewed Nucleic acid binding
P78352 BXGT011836 Disks large homolog 4 1742 reviewed Receptor
P98170 BXGT012231 E3 ubiquitin-protein ligase XIAP 331 reviewed Enzyme modulator
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01105 BXGT012569 Protein SET 6418 reviewed Enzyme modulator
Q01959 BXGT012624 Sodium-dependent dopamine transporter 6531 reviewed Transporter
Q02779 BXGT012670 Mitogen-activated protein kinase kinase kinase 10 4294 reviewed Kinase
Q02790 BXGT012672 Peptidyl-prolyl cis-trans isomerase FKBP4 2288 reviewed Enzyme
Q03393 BXGT012711 6-pyruvoyl tetrahydrobiopterin synthase 5805 reviewed
Q05940 BXGT012846 Synaptic vesicular amine transporter 6571 reviewed Transporter
Q06418 BXGT012875 Tyrosine-protein kinase receptor TYRO3 7301 reviewed Kinase
Q06787 BXGT012890 Synaptic functional regulator FMR1 2332 reviewed Nucleic acid binding
Q06830 BXGT012894 Peroxiredoxin-1 5052 reviewed Enzyme
Q07075 BXGT012917 Glutamyl aminopeptidase 2028 reviewed Enzyme
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha 5465 reviewed Nuclear receptor
Q07954 BXGT012950 Prolow-density lipoprotein receptor-related protein 1 4035 reviewed
Q08881 BXGT013012 Tyrosine-protein kinase ITK/TSK 3702 reviewed Kinase
Q09472 BXGT013038 Histone acetyltransferase p300 2033 reviewed
Q12879 BXGT013275 Glutamate receptor ionotropic, NMDA 2A 2903 reviewed Ion channel
Q12882 BXGT013276 Dihydropyrimidine dehydrogenase [NADP(+)] 1806 reviewed Enzyme
Q13324 BXGT013340 Corticotropin-releasing factor receptor 2 1395 reviewed G-protein coupled receptor
Q13451 BXGT013356 Peptidyl-prolyl cis-trans isomerase FKBP5 2289 reviewed Enzyme
Q13555 BXGT013375 Calcium/calmodulin-dependent protein kinase type II subunit gamma 818 reviewed Kinase
Q13671 BXGT013391 Ras and Rab interactor 1 9610 reviewed Enzyme modulator
Q13936 BXGT013404 Voltage-dependent L-type calcium channel subunit alpha-1C 775 reviewed Ion channel
Q13938 BXGT013405 Calcyphosin 828 reviewed
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14117 BXGT013443 Dihydropyrimidinase 1807 reviewed Enzyme
Q14416 BXGT013468 Metabotropic glutamate receptor 2 2912 reviewed G-protein coupled receptor
Q14457 BXGT013472 Beclin-1 8678 reviewed Enzyme modulator
Q15303 BXGT013557 Receptor tyrosine-protein kinase erbB-4 2066 reviewed Kinase
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16620 BXGT013645 BDNF/NT-3 growth factors receptor 4915 reviewed Kinase
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16739 BXGT013663 Ceramide glucosyltransferase 7357 reviewed Enzyme
Q59FK2 BXGT015276 Selenocysteine lyase variant 51540 unreviewed
Q5Y7D3 BXGT015912 HLA class II histocompatibility antigen DQ beta chain 3119 unreviewed
Q6W5P4 BXGT016588 Neuropeptide S receptor 387129 reviewed
Q86V24 BXGT017615 Adiponectin receptor protein 2 79602 reviewed Receptor
Q8IVA8 BXGT018342 Glutamate decarboxylase 1 (Brain, 67kDa) 2571 unreviewed
Q8NBP7 BXGT018541 Proprotein convertase subtilisin/kexin type 9 255738 reviewed Enzyme
Q8NFD2 BXGT018559 Ankyrin repeat and protein kinase domain-containing protein 1 255239 reviewed Kinase
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96EN8 BXGT019649 Molybdenum cofactor sulfurase 55034 reviewed
Q96I15 BXGT019674 Selenocysteine lyase 51540 reviewed Enzyme
Q99259 BXGT019915 Glutamate decarboxylase 1 2571 reviewed Enzyme
Q99572 BXGT019935 P2X purinoceptor 7 5027 reviewed Ion channel
Q99683 BXGT019947 Mitogen-activated protein kinase kinase kinase 5 4217 reviewed Kinase
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 10280 reviewed
Q9BY08 BXGT020177 Emopamil-binding protein-like 84650 reviewed Enzyme
Q9BYW2 BXGT020192 Histone-lysine N-methyltransferase SETD2 29072 reviewed Epigenetic regulator
Q9GZT4 BXGT020424 Serine racemase 63826 reviewed Enzyme
Q9NR97 BXGT021182 Toll-like receptor 8 51311 reviewed
Q9NRG1 BXGT021186 Phosphoribosyltransferase domain-containing protein 1 56952 reviewed Enzyme
Q9NZJ5 BXGT021275 Eukaryotic translation initiation factor 2-alpha kinase 3 9451 reviewed Kinase
Q9P2W7 BXGT021306 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 27087 reviewed Enzyme
Q9UKV8 BXGT021752 Protein argonaute-2 27161 reviewed
Q9UM47 BXGT021772 Neurogenic locus notch homolog protein 3 4854 reviewed
Q9UPY3 BXGT021802 Endoribonuclease Dicer 23405 reviewed Enzyme
Q92847 BXGT022673 Growth hormone secretagogue receptor type 1 2693 reviewed G-protein coupled receptor
O60936 BXGT022857 Nucleolar protein 3 8996 reviewed
P17752 BXGT023118 Tryptophan 5-hydroxylase 1 7166 reviewed
O15467 BXGT023188 C-C motif chemokine 16 6360 reviewed Signaling
Q8IX03 BXGT024000 Protein KIBRA 23286 reviewed
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
P27918 BXGT025485 Properdin 5199 reviewed
O43613 BXGT025666 Orexin receptor type 1 3061 reviewed G-protein coupled receptor
Q86SQ9 BXGT025875 Dehydrodolichyl diphosphate synthase complex subunit DHDDS 79947 reviewed Enzyme
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease