Showing entry for Sodium/nucleoside cotransporter 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004631
Protein NameSodium/nucleoside cotransporter 2
Uniport IdO43868
GeneSLC28A2
Gene Id9153
DomainGate; Nucleos_tra2_C; Nucleos_tra2_N
Pfam PF07670   PF07662   PF01773  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0032238 adenosine transport
Biological Process GO:0045117 azole transmembrane transport
Biological Process GO:0035340 inosine transport
Biological Process GO:0006836 neurotransmitter transport
Biological Process GO:0006139 nucleobase-containing compound metabolic process
Biological Process GO:1901642 nucleoside transmembrane transport
Biological Process GO:1904823 purine nucleobase transmembrane transport
Biological Process GO:0015860 purine nucleoside transmembrane transport
Biological Process GO:0072531 pyrimidine-containing compound transmembrane transport
Biological Process GO:0001895 retina homeostasis
Biological Process GO:0150104 transport across blood-brain barrier
Biological Process GO:0015862 uridine transport
molecular function GO:1901474 azole transmembrane transporter activity
molecular function GO:0005326 neurotransmitter transmembrane transporter activity
molecular function GO:0005415 nucleoside:sodium symporter activity
molecular function GO:0005337 nucleoside transmembrane transporter activity
molecular function GO:0005345 purine nucleobase transmembrane transporter activity
molecular function GO:0015211 purine nucleoside transmembrane transporter activity
molecular function GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity
molecular function GO:0015293 symporter activity
molecular function GO:0015213 uridine transmembrane transporter activity
cellular component GO:0031526 brush border membrane
cellular component GO:0030135 coated vesicle
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0012506 vesicle membrane
Reactome
Pathway Id Pathway Name
R-HSA-382551 Transport of small molecules
R-HSA-425397 Transport of vitamins, nucleosides, and related molecules
R-HSA-425407 SLC-mediated transmembrane transport
R-HSA-83936 Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0011853 BXGD000752 Diabetes Mellitus, Experimental Nutritional and Metabolic Diseases; Endocrine System Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0021368 BXGD001502 Inflammation Pathological Conditions, Signs and Symptoms
C0023787 BXGD001698 Lipodystrophy Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0524910 BXGD009248 Hepatitis C, Chronic Digestive System Diseases; Infections
C0740394 BXGD009989 Hyperuricemia Pathological Conditions, Signs and Symptoms
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002605 Adenosine 267.24
BXGC0003788 Phlororrhizin 436.41
BXGC0044087 Uridine 244.07
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein