adisease

Showing entry for Lipodystrophy

General Disease Information
BXGD Id	BXGD001698
Disease Name	Lipodystrophy
Disease CUI Id	C0023787
MeSH Codes	C18 C17
Disease Class Name	Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0003549
Human Phenotype Ontology Term	Abnormality of connective tissue
Disease Ontology Id	DOID:0014667 DOID:630 DOID:7
Disease Ontology Class Name	disease of metabolism; genetic disease; disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O00337	BXGT003911	Sodium/nucleoside cotransporter 1	9154	reviewed	Transporter
O00767	BXGT003949	Acyl-CoA desaturase	6319	reviewed
O15120	BXGT004129	1-acyl-sn-glycerol-3-phosphate acyltransferase beta	10555	reviewed
O15305	BXGT004152	Phosphomannomutase 2	5373	reviewed	Enzyme
O15379	BXGT004159	Histone deacetylase 3	8841	reviewed	Epigenetic regulator
O43293	BXGT004584	Death-associated protein kinase 3	1613	reviewed	Kinase
O43868	BXGT004631	Sodium/nucleoside cotransporter 2	9153	reviewed	Transporter
O60240	BXGT004860	Perilipin-1	5346	reviewed
O60706	BXGT004896	ATP-binding cassette sub-family C member 9	10060	reviewed	Transporter
O75112	BXGT005099	LIM domain-binding protein 3	11155	reviewed	Cellular structure
O75496	BXGT005132	Geminin	51053	reviewed
O75844	BXGT005156	CAAX prenyl protease 1 homolog	10269	reviewed	Enzyme
O95750	BXGT005395	Fibroblast growth factor 19	9965	reviewed	Signaling
P00505	BXGT005560	Aspartate aminotransferase, mitochondrial	2806	reviewed
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P01100	BXGT005727	Proto-oncogene c-Fos	2353	reviewed	Transcription factor
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01303	BXGT005748	Pro-neuropeptide Y	4852	reviewed	Signaling
P01308	BXGT005749	Insulin	3630	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P02461	BXGT005880	Collagen alpha-1(III) chain	1281	reviewed
P02511	BXGT005885	Alpha-crystallin B chain	1410	reviewed
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02656	BXGT005913	Apolipoprotein C-III	345	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P04049	BXGT006133	RAF proto-oncogene serine/threonine-protein kinase	5894	reviewed	Kinase
P04066	BXGT006142	Tissue alpha-L-fucosidase	2517	reviewed
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04440	BXGT006216	HLA class II histocompatibility antigen, DP beta 1 chain	3115	reviewed	Immune response
P04818	BXGT006269	Thymidylate synthase	7298	reviewed	Enzyme
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06213	BXGT006425	Insulin receptor	3643	reviewed	Kinase
P06858	BXGT006515	Lipoprotein lipase	4023	reviewed	Enzyme
P08069	BXGT006723	Insulin-like growth factor 1 receptor	3480	reviewed	Kinase
P08235	BXGT006751	Mineralocorticoid receptor	4306	reviewed	Nuclear receptor
P08575	BXGT006793	Receptor-type tyrosine-protein phosphatase C	5788	reviewed	Enzyme
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P09493	BXGT006900	Tropomyosin alpha-1 chain	7168	reviewed	Cellular structure
P09619	BXGT006911	Platelet-derived growth factor receptor beta	5159	reviewed	Kinase
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10147	BXGT007543	C-C motif chemokine 3	6348	reviewed	Signaling
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P15090	BXGT008079	Fatty acid-binding protein, adipocyte	2167	reviewed
P16871	BXGT008269	Interleukin-7 receptor subunit alpha	3575	reviewed	Receptor
P18206	BXGT008389	Vinculin	7414	reviewed
P19429	BXGT008479	Troponin I, cardiac muscle	7137	reviewed	Cellular structure
P21333	BXGT008638	Filamin-A	2316	reviewed
P21673	BXGT008676	Diamine acetyltransferase 1	6303	reviewed
P23945	BXGT008931	Follicle-stimulating hormone receptor	2492	reviewed	G-protein coupled receptor
P27986	BXGT009216	Phosphatidylinositol 3-kinase regulatory subunit alpha	5295	reviewed	Kinase
P28070	BXGT009230	Proteasome subunit beta type-4	5692	reviewed
P28907	BXGT009301	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	952	reviewed	Enzyme
P29350	BXGT009335	Tyrosine-protein phosphatase non-receptor type 6	5777	reviewed
P29373	BXGT009337	Cellular retinoic acid-binding protein 2	1382	reviewed
P31040	BXGT009503	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	6389	reviewed	Enzyme
P31751	BXGT009576	RAC-beta serine/threonine-protein kinase	208	reviewed	Kinase
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35555	BXGT009845	Fibrillin-1	2200	reviewed	Calcium-binding protein
P35558	BXGT009847	Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	5105	reviewed	Kinase
P35573	BXGT009850	Glycogen debranching enzyme	178	reviewed	Enzyme
P36021	BXGT009893	Monocarboxylate transporter 8	6567	reviewed	Transporter
P36956	BXGT009947	Sterol regulatory element-binding protein 1	6720	reviewed
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P45379	BXGT010459	Troponin T, cardiac muscle	7139	reviewed	Cellular structure
P48051	BXGT010611	G protein-activated inward rectifier potassium channel 2	3763	reviewed	Ion channel
P48147	BXGT010620	Prolyl endopeptidase	5550	reviewed	Enzyme
P48357	BXGT010627	Leptin receptor	3953	reviewed	Signaling
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P49585	BXGT010712	Choline-phosphate cytidylyltransferase A	5130	reviewed
P49768	BXGT010740	Presenilin-1	5663	reviewed	Enzyme
P49810	BXGT010747	Presenilin-2	5664	reviewed	Enzyme
P50120	BXGT010773	Retinol-binding protein 2	5948	reviewed
P55265	BXGT011117	Double-stranded RNA-specific adenosine deaminase	103	reviewed	Enzyme
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P63316	BXGT011517	Troponin C, slow skeletal and cardiac muscles	7134	reviewed	Calcium-binding protein
Q00987	BXGT012559	E3 ubiquitin-protein ligase Mdm2	4193	reviewed	Nucleic acid binding
Q07869	BXGT012945	Peroxisome proliferator-activated receptor alpha	5465	reviewed	Nuclear receptor
Q13698	BXGT013392	Voltage-dependent L-type calcium channel subunit alpha-1S	779	reviewed	Ion channel
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14126	BXGT013446	Desmoglein-2	1829	reviewed	Cell adhesion
Q14191	BXGT013452	Werner syndrome ATP-dependent helicase	7486	reviewed	Enzyme
Q14524	BXGT013478	Sodium channel protein type 5 subunit alpha	6331	reviewed	Ion channel
Q14542	BXGT013482	Equilibrative nucleoside transporter 2	3177	reviewed	Transporter
Q15843	BXGT013608	NEDD8	4738	reviewed	Nucleic acid binding
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q30201	BXGT014297	Hereditary hemochromatosis protein	3077	reviewed
Q6NUK1	BXGT016429	Calcium-binding mitochondrial carrier protein SCaMC-1	29957	reviewed	Transporter
Q86V24	BXGT017615	Adiponectin receptor protein 2	79602	reviewed	Receptor
Q8WZ42	BXGT019023	Titin	7273	reviewed	Kinase
Q92731	BXGT019366	Estrogen receptor beta	2100	reviewed	Nuclear receptor
Q96AC1	BXGT019617	Fermitin family homolog 2	10979	reviewed
Q96BN8	BXGT019625	Ubiquitin thioesterase otulin	90268	reviewed
Q99808	BXGT019964	Equilibrative nucleoside transporter 1	2030	reviewed	Transporter
Q9H251	BXGT020449	Cadherin-23	64072	reviewed
Q9HAS3	BXGT020507	Solute carrier family 28 member 3	64078	reviewed	Transporter
Q9NNW7	BXGT021139	Thioredoxin reductase 2, mitochondrial	10587	reviewed	Enzyme
Q9P0J0	BXGT021287	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	51079	reviewed	Enzyme
Q9UBV7	BXGT021665	Beta-1,4-galactosyltransferase 7	11285	reviewed
Q9UGN5	BXGT021688	Poly [ADP-ribose] polymerase 2	10038	reviewed
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
Q9Y3Z3	BXGT022268	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	25939	reviewed
O14490	BXGT023570	Disks large-associated protein 1	9229	reviewed	Receptor
P29590	BXGT024350	Protein PML	5371	reviewed
O95140	BXGT024482	Mitofusin-2	9927	reviewed	Enzyme
Q96A54	BXGT024681	Adiponectin receptor protein 1	51094	reviewed	Receptor
Q9H040	BXGT024831	SprT-like domain-containing protein Spartan	83932	reviewed
Q9BY76	BXGT025687	Angiopoietin-related protein 4	51129	reviewed	Signaling

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}