Showing entry for S-formylglutathione hydrolase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT007611
Protein NameS-formylglutathione hydrolase
Uniport IdP10768
GeneESD
Gene Id2098
DomainEsterase
Pfam PF00756  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
1. Metabolism 1.0 Global and overview maps hsa01200 Carbon metabolism
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0046294 formaldehyde catabolic process
Biological Process GO:1901687 glutathione derivative biosynthetic process
molecular function GO:0052689 carboxylic ester hydrolase activity
molecular function GO:0016788 hydrolase activity, acting on ester bonds
molecular function GO:0042802 identical protein binding
molecular function GO:0047374 methylumbelliferyl-acetate deacetylase activity
molecular function GO:0018738 S-formylglutathione hydrolase activity
cellular component GO:0031410 cytoplasmic vesicle
cellular component GO:0005829 cytosol
cellular component GO:0005788 endoplasmic reticulum lumen
cellular component GO:0070062 extracellular exosome
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-156580 Phase II - Conjugation of compounds
R-HSA-156590 Glutathione conjugation
R-HSA-211859 Biological oxidations
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001430 BXGD000054 Adenoma Neoplasms
C0003129 BXGD000182 Anoxemia Pathological Conditions, Signs and Symptoms
C0003130 BXGD000183 Anoxia Pathological Conditions, Signs and Symptoms
C0004936 BXGD000295 Mental disorders Mental Disorders
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0019202 BXGD001302 Hepatolenticular Degeneration Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases; Nervous System Diseases
C0026499 BXGD001905 Monosomy Pathological Conditions, Signs and Symptoms
C0027651 BXGD002009 Neoplasms Neoplasms
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0032290 BXGD002345 Aspiration Pneumonia Infections; Respiratory Tract Diseases
C0032584 BXGD002363 polyps Pathological Conditions, Signs and Symptoms
C0035335 BXGD002540 Retinoblastoma Neoplasms; Eye Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0041296 BXGD002903 Tuberculosis Infections
C0042164 BXGD002965 Uveitis Eye Diseases
C0086743 BXGD003308 Osteoarthrosis Deformans Musculoskeletal Diseases
C0149931 BXGD003388 Migraine Disorders Nervous System Diseases
C0152095 BXGD003537 Patau syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Cardiovascular Diseases
C0205645 BXGD004097 Adenocarcinoma, Tubular Neoplasms
C0220668 BXGD004317 Congenital contractural arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0242184 BXGD005140 Hypoxia Pathological Conditions, Signs and Symptoms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0302332 BXGD006841 Poisoning syndrome
C0349530 BXGD007916 Early gastric cancer Digestive System Diseases; Neoplasms
C0521158 BXGD009130 Recurrent tumor
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700292 BXGD009884 Hypoxemia Pathological Conditions, Signs and Symptoms
C0751483 BXGD010467 Familial Retinoblastoma Neoplasms; Eye Diseases
C0751484 BXGD010468 Sporadic Retinoblastoma Neoplasms; Eye Diseases
C0854914 BXGD011048 Retinoblastoma bilateral Neoplasms; Eye Diseases
C1261473 BXGD011855 Sarcoma Neoplasms
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1761609 BXGD013751 Aspiration pneumonitis Infections; Respiratory Tract Diseases
C2985280 BXGD018223 Blood Protein Measurement
C4551686 BXGD023391 Malignant neoplasm of soft tissue Neoplasms
C4749304 BXGD024055 Monosomy 13q14 syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000989 Glutathione 307.32
BXGC0002586 Calcium 40.08
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein