adisease

Showing entry for Anoxia

General Disease Information
BXGD Id	BXGD000183
Disease Name	Anoxia
Disease CUI Id	C0003130
MeSH Codes	C23
Disease Class Name	Pathological Conditions, Signs and Symptoms
Semantic Type	Pathologic Function
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00141	BXGT003882	Serine/threonine-protein kinase Sgk1	6446	reviewed	Kinase
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00767	BXGT003949	Acyl-CoA desaturase	6319	reviewed
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O14763	BXGT004093	Tumor necrosis factor receptor superfamily member 10B	8795	reviewed
O14965	BXGT004117	Aurora kinase A	6790	reviewed	Kinase
O15123	BXGT004130	Angiopoietin-2	285	reviewed	Signaling
O15269	BXGT004145	Serine palmitoyltransferase 1	10558	reviewed	Enzyme
O15374	BXGT004157	Monocarboxylate transporter 5	9122	reviewed	Transporter
O15392	BXGT004162	Baculoviral IAP repeat-containing protein 5	332	reviewed	Enzyme modulator
O43255	BXGT004579	E3 ubiquitin-protein ligase SIAH2	6478	reviewed
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
O75390	BXGT005123	Citrate synthase, mitochondrial	1431	reviewed	Enzyme
O95069	BXGT005348	Potassium channel subfamily K member 2	3776	reviewed	Ion channel
O95718	BXGT005392	Steroid hormone receptor ERR2	2103	reviewed	Nuclear receptor
P00750	BXGT005642	Tissue-type plasminogen activator	5327	reviewed	Enzyme
P00813	BXGT005667	Adenosine deaminase	100	reviewed	Enzyme
P01100	BXGT005727	Proto-oncogene c-Fos	2353	reviewed	Transcription factor
P01106	BXGT005730	Myc proto-oncogene protein	4609	reviewed	Transcription factor
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P02647	BXGT005908	Apolipoprotein A-I	335	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02730	BXGT005935	Band 3 anion transport protein	6521	reviewed	Transporter
P02795	BXGT005968	Metallothionein-2	4502	reviewed
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P03915	BXGT006114	NADH-ubiquinone oxidoreductase chain 5	4540	reviewed	Enzyme
P03950	BXGT006116	Angiogenin	283	reviewed
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04406	BXGT006207	Glyceraldehyde-3-phosphate dehydrogenase	2597	reviewed	Enzyme
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	2064	reviewed	Kinase
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05062	BXGT006305	Fructose-bisphosphate aldolase B	229	reviewed
P05067	BXGT006306	Amyloid-beta precursor protein	351	reviewed	Enzyme modulator
P05106	BXGT006315	Integrin beta-3	3690	reviewed	Receptor
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P05412	BXGT006354	Transcription factor AP-1	3725	reviewed	Transcription factor
P05556	BXGT006368	Integrin beta-1	3688	reviewed	Receptor
P06239	BXGT006427	Tyrosine-protein kinase Lck	3932	reviewed	Kinase
P06576	BXGT006454	ATP synthase subunit beta, mitochondrial	506	reviewed	Transporter
P07384	BXGT006619	Calpain-1 catalytic subunit	823	reviewed	Enzyme
P07996	BXGT006710	Thrombospondin-1	7057	reviewed
P08034	BXGT006716	Gap junction beta-1 protein	2705	reviewed	Cell-cell junction
P08047	BXGT006720	Transcription factor Sp1	6667	reviewed	Nucleic acid binding
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	1129	reviewed	G-protein coupled receptor
P08476	BXGT006774	Inhibin beta A chain	3624	reviewed	Signaling
P08709	BXGT006818	Coagulation factor VII	2155	reviewed	Enzyme
P08833	BXGT006827	Insulin-like growth factor-binding protein 1	3484	reviewed	Enzyme modulator
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P0DMV8	BXGT007509	Heat shock 70 kDa protein 1A	3304	reviewed
P0DMV9	BXGT007510	Heat shock 70 kDa protein 1B	3304	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10275	BXGT007552	Androgen receptor	367	reviewed	Nuclear receptor
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10599	BXGT007583	Thioredoxin	7295	reviewed
P10600	BXGT007584	Transforming growth factor beta-3 proprotein	7043	reviewed	Signaling
P10646	BXGT007598	Tissue factor pathway inhibitor	7035	reviewed	Enzyme modulator
P10768	BXGT007611	S-formylglutathione hydrolase	2098	reviewed	Enzyme
P11021	BXGT007644	Endoplasmic reticulum chaperone BiP	3309	reviewed
P11166	BXGT007661	Solute carrier family 2, facilitated glucose transporter member 1	6513	reviewed	Transporter
P11169	BXGT007664	Solute carrier family 2, facilitated glucose transporter member 3	6515	reviewed	Transporter
P11215	BXGT007672	Integrin alpha-M	3684	reviewed
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	1128	reviewed	G-protein coupled receptor
P11474	BXGT007710	Steroid hormone receptor ERR1	2101	reviewed	Nuclear receptor
P11511	BXGT007717	Aromatase	1588	reviewed	Enzyme
P12931	BXGT007859	Proto-oncogene tyrosine-protein kinase Src	6714	reviewed	Kinase
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P13569	BXGT007923	Cystic fibrosis transmembrane conductance regulator	1080	reviewed	Ion channel
P13674	BXGT007942	Prolyl 4-hydroxylase subunit alpha-1	5033	reviewed
P14174	BXGT007991	Macrophage migration inhibitory factor	4282	reviewed
P14210	BXGT007994	Hepatocyte growth factor	3082	reviewed	Enzyme
P14625	BXGT008029	Endoplasmin	7184	reviewed	Chaperone
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15531	BXGT008136	Nucleoside diphosphate kinase A	4830	reviewed	Kinase
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P15880	BXGT008165	40S ribosomal protein S2	6187	reviewed	Nucleic acid binding
P15941	BXGT008176	Mucin-1	4582	reviewed
P16050	BXGT008184	Arachidonate 15-lipoxygenase	246	reviewed	Enzyme
P16220	BXGT008206	Cyclic AMP-responsive element-binding protein 1	1385	reviewed
P17538	BXGT008314	Chymotrypsinogen B	1504	reviewed	Enzyme
P17612	BXGT008322	cAMP-dependent protein kinase catalytic subunit alpha	5566	reviewed	Kinase
P17936	BXGT008357	Insulin-like growth factor-binding protein 3	3486	reviewed	Enzyme modulator
P17948	BXGT008358	Vascular endothelial growth factor receptor 1	2321	reviewed	Kinase
P18146	BXGT008384	Early growth response protein 1	1958	reviewed	Nucleic acid binding
P18848	BXGT008432	Cyclic AMP-dependent transcription factor ATF-4	468	reviewed
P19320	BXGT008470	Vascular cell adhesion protein 1	7412	reviewed
P19838	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	4790	reviewed	Transcription factor
P20292	BXGT008561	Arachidonate 5-lipoxygenase-activating protein	241	reviewed	Enzyme
P21399	BXGT008646	Cytoplasmic aconitate hydratase	48	reviewed	Enzyme
P21580	BXGT008666	Tumor necrosis factor alpha-induced protein 3	7128	reviewed	Enzyme
P21583	BXGT008667	Kit ligand	4254	reviewed
P22460	BXGT008774	Potassium voltage-gated channel subfamily A member 5	3741	reviewed	Ion channel
P23458	BXGT008868	Tyrosine-protein kinase JAK1	3716	reviewed	Kinase
P23526	BXGT008878	Adenosylhomocysteinase	191	reviewed	Enzyme
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P24530	BXGT008975	Endothelin receptor type B	1910	reviewed	G-protein coupled receptor
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P27540	BXGT009190	Aryl hydrocarbon receptor nuclear translocator	405	reviewed	Transcription factor
P27708	BXGT009202	CAD protein	790	reviewed	Enzyme
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P28562	BXGT009270	Dual specificity protein phosphatase 1	1843	reviewed
P29275	BXGT009328	Adenosine receptor A2b	136	reviewed	G-protein coupled receptor
P29401	BXGT009344	Transketolase	7086	reviewed	Enzyme
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P29475	BXGT009353	Nitric oxide synthase, brain	4842	reviewed
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35398	BXGT009825	Nuclear receptor ROR-alpha	6095	reviewed	Nuclear receptor
P35610	BXGT009855	Sterol O-acyltransferase 1	6646	reviewed	Enzyme
P35869	BXGT009877	Aryl hydrocarbon receptor	196	reviewed	Transcription factor
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P36507	BXGT009923	Dual specificity mitogen-activated protein kinase kinase 2	5605	reviewed	Kinase
P36897	BXGT009941	TGF-beta receptor type-1	7046	reviewed	Kinase
P36955	BXGT009946	Pigment epithelium-derived factor	5176	reviewed	Enzyme modulator
P36956	BXGT009947	Sterol regulatory element-binding protein 1	6720	reviewed
P37173	BXGT009970	TGF-beta receptor type-2	7048	reviewed	Kinase
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P40337	BXGT010174	von Hippel-Lindau disease tumor suppressor	7428	reviewed	Enzyme
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P41227	BXGT010238	N-alpha-acetyltransferase 10	8260	reviewed	Enzyme
P42224	BXGT010286	Signal transducer and activator of transcription 1-alpha/beta	6772	reviewed	Nucleic acid binding
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P43405	BXGT010386	Tyrosine-protein kinase SYK	6850	reviewed	Kinase
P46059	BXGT010500	Solute carrier family 15 member 1	6564	reviewed	Transporter
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P47989	BXGT010602	Xanthine dehydrogenase/oxidase	7498	reviewed	Enzyme
P48052	BXGT010612	Carboxypeptidase A2	1358	reviewed	Enzyme
P48061	BXGT010616	Stromal cell-derived factor 1	6387	reviewed
P49327	BXGT010694	Fatty acid synthase	2194	reviewed	Enzyme
P49748	BXGT010733	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	37	reviewed	Enzyme
P49763	BXGT010737	Placenta growth factor	5228	reviewed	Signaling
P49768	BXGT010740	Presenilin-1	5663	reviewed	Enzyme
P50591	BXGT010814	Tumor necrosis factor ligand superfamily member 10	8743	reviewed	Signaling
P51589	BXGT010867	Cytochrome P450 2J2	1573	reviewed
P51692	BXGT010885	Signal transducer and activator of transcription 5B	6777	reviewed	Nucleic acid binding
P54646	BXGT011062	5'-AMP-activated protein kinase catalytic subunit alpha-2	5563	reviewed	Kinase
P55211	BXGT011111	Caspase-9	842	reviewed	Enzyme
P55263	BXGT011115	Adenosine kinase	132	reviewed	Kinase
P56373	BXGT011164	P2X purinoceptor 3	5024	reviewed	Ion channel
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P62508	BXGT011431	Estrogen-related receptor gamma	2104	reviewed	Nuclear receptor
P63092	BXGT011495	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	2778	reviewed
P63165	BXGT011506	Small ubiquitin-related modifier 1	7341	reviewed
P68400	BXGT011599	Casein kinase II subunit alpha	1457	reviewed	Kinase
P80365	BXGT011895	Corticosteroid 11-beta-dehydrogenase isozyme 2	3291	reviewed	Enzyme
P81605	BXGT011954	Dermcidin	117159	reviewed
P84022	BXGT012027	Mothers against decapentaplegic homolog 3	4088	reviewed	Transcription factor
Q02750	BXGT012662	Dual specificity mitogen-activated protein kinase kinase 1	5604	reviewed	Kinase
Q02763	BXGT012667	Angiopoietin-1 receptor	7010	reviewed	Kinase
Q03405	BXGT012713	Urokinase plasminogen activator surface receptor	5329	reviewed
Q04756	BXGT012780	Hepatocyte growth factor activator	3083	reviewed	Enzyme
Q05655	BXGT012832	Protein kinase C delta type	5580	reviewed	Kinase
Q06830	BXGT012894	Peroxiredoxin-1	5052	reviewed	Enzyme
Q07812	BXGT012940	Apoptosis regulator BAX	581	reviewed	Signaling
Q07817	BXGT012941	Bcl-2-like protein 1	598	reviewed	Signaling
Q12791	BXGT013264	Calcium-activated potassium channel subunit alpha-1	3778	reviewed	Ion channel
Q12797	BXGT013266	Aspartyl/asparaginyl beta-hydroxylase	444	reviewed
Q12809	BXGT013267	Potassium voltage-gated channel subfamily H member 2	3757	reviewed	Ion channel
Q13131	BXGT013314	5'-AMP-activated protein kinase catalytic subunit alpha-1	5562	reviewed	Kinase
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q13363	BXGT013344	C-terminal-binding protein 1	1487	reviewed	Transcription factor
Q13418	BXGT013351	Integrin-linked protein kinase	3611	reviewed	Kinase
Q13489	BXGT013364	Baculoviral IAP repeat-containing protein 3	330	reviewed	Enzyme modulator
Q13535	BXGT013370	Serine/threonine-protein kinase ATR	545	reviewed	Kinase
Q13547	BXGT013373	Histone deacetylase 1	3065	reviewed	Epigenetic regulator
Q14011	BXGT013436	Cold-inducible RNA-binding protein	1153	reviewed	Nucleic acid binding
Q14432	BXGT013469	cGMP-inhibited 3',5'-cyclic phosphodiesterase A	5139	reviewed
Q14524	BXGT013478	Sodium channel protein type 5 subunit alpha	6331	reviewed	Ion channel
Q14683	BXGT013500	Structural maintenance of chromosomes protein 1A	8243	reviewed
Q15389	BXGT013564	Angiopoietin-1	284	reviewed	Signaling
Q16539	BXGT013634	Mitogen-activated protein kinase 14	1432	reviewed	Kinase
Q16611	BXGT013644	Bcl-2 homologous antagonist/killer	578	reviewed	Signaling
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q16790	BXGT013670	Carbonic anhydrase 9	768	reviewed
Q16875	BXGT013686	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3	5209	reviewed	Kinase
Q86Y07	BXGT017631	Serine/threonine-protein kinase VRK2	7444	reviewed	Kinase
Q8NBS9	BXGT018543	Thioredoxin domain-containing protein 5	81567	reviewed
Q8WWM9	BXGT019001	Cytoglobin	114757	reviewed
Q92769	BXGT019370	Histone deacetylase 2	3066	reviewed	Epigenetic regulator
Q92831	BXGT019380	Histone acetyltransferase KAT2B	8850	reviewed
Q99497	BXGT019926	Protein/nucleic acid deglycase DJ-1	11315	reviewed	Enzyme
Q99728	BXGT019956	BRCA1-associated RING domain protein 1	580	reviewed
Q99814	BXGT019965	Endothelial PAS domain-containing protein 1	2034	reviewed	Transcription factor
Q9GZT9	BXGT020425	Egl nine homolog 1	54583	reviewed
Q9H3M7	BXGT020462	Thioredoxin-interacting protein	10628	reviewed
Q9H3R0	BXGT020465	Lysine-specific demethylase 4C	23081	reviewed
Q9H4B4	BXGT020474	Serine/threonine-protein kinase PLK3	1263	reviewed	Kinase
Q9H6Z9	BXGT020488	Egl nine homolog 3	112399	reviewed
Q9NPC2	BXGT021150	Potassium channel subfamily K member 9	51305	reviewed	Ion channel
Q9NPH5	BXGT021159	NADPH oxidase 4	50507	reviewed	Enzyme
Q9NXG6	BXGT021246	Transmembrane prolyl 4-hydroxylase	54681	reviewed
Q9NYA1	BXGT021254	Sphingosine kinase 1	8877	reviewed	Kinase
Q9NZJ5	BXGT021275	Eukaryotic translation initiation factor 2-alpha kinase 3	9451	reviewed	Kinase
Q9UBL9	BXGT021656	P2X purinoceptor 2	22953	reviewed	Ion channel
Q9UQF0	BXGT021812	Syncytin-1	30816	reviewed
Q9Y5S8	BXGT022302	NADPH oxidase 1	27035	reviewed
P19235	BXGT022895	Erythropoietin receptor	2057	reviewed	Receptor
P36873	BXGT023107	Serine/threonine-protein phosphatase PP1-gamma catalytic subunit	5501	reviewed	Enzyme
Q9H2S1	BXGT023455	Small conductance calcium-activated potassium channel protein 2	3781	reviewed	Ion channel
P62263	BXGT026033	40S ribosomal protein S14	6208	reviewed	Nucleic acid binding

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}