adisease

Showing entry for Monosomy

General Disease Information
BXGD Id	BXGD001905
Disease Name	Monosomy
Disease CUI Id	C0026499
MeSH Codes	C23
Disease Class Name	Pathological Conditions, Signs and Symptoms
Semantic Type	Congenital Abnormality
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O15392	BXGT004162	Baculoviral IAP repeat-containing protein 5	332	reviewed	Enzyme modulator
O15550	BXGT004179	Lysine-specific demethylase 6A	7403	reviewed	Epigenetic regulator
O43854	BXGT004630	EGF-like repeat and discoidin I-like domain-containing protein 3	10085	reviewed	Enzyme
O75874	BXGT005157	Isocitrate dehydrogenase [NADP] cytoplasmic	3417	reviewed
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P00519	BXGT005570	Tyrosine-protein kinase ABL1	25	reviewed	Kinase
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P01106	BXGT005730	Myc proto-oncogene protein	4609	reviewed	Transcription factor
P01111	BXGT005731	GTPase NRas	4893	reviewed	Enzyme modulator
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	2064	reviewed	Kinase
P04629	BXGT006239	High affinity nerve growth factor receptor	4914	reviewed	Kinase
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04792	BXGT006264	Heat shock protein beta-1	3315	reviewed
P05067	BXGT006306	Amyloid-beta precursor protein	351	reviewed	Enzyme modulator
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P05230	BXGT006344	Fibroblast growth factor 1	2246	reviewed	Signaling
P06401	BXGT006436	Progesterone receptor	5241	reviewed	Nuclear receptor
P06748	BXGT006497	Nucleophosmin	4869	reviewed	Chaperone
P07333	BXGT006602	Macrophage colony-stimulating factor 1 receptor	1436	reviewed	Kinase
P08069	BXGT006723	Insulin-like growth factor 1 receptor	3480	reviewed	Kinase
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08236	BXGT006752	Beta-glucuronidase	2990	reviewed
P08397	BXGT006768	Porphobilinogen deaminase	3145	reviewed	Enzyme
P08670	BXGT006810	Vimentin	7431	reviewed
P0CE72	BXGT007460	Oncomodulin-1	654231	reviewed
P0DN79	BXGT007511	Cystathionine beta-synthase-like protein	875	reviewed
P10301	BXGT007556	Ras-related protein R-Ras	6237	reviewed	Enzyme modulator
P10646	BXGT007598	Tissue factor pathway inhibitor	7035	reviewed	Enzyme modulator
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P10768	BXGT007611	S-formylglutathione hydrolase	2098	reviewed	Enzyme
P11215	BXGT007672	Integrin alpha-M	3684	reviewed
P11274	BXGT007681	Breakpoint cluster region protein	613	reviewed	Enzyme modulator
P11388	BXGT007697	DNA topoisomerase 2-alpha	7153	reviewed
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P16234	BXGT008209	Platelet-derived growth factor receptor alpha	5156	reviewed	Kinase
P17936	BXGT008357	Insulin-like growth factor-binding protein 3	3486	reviewed	Enzyme modulator
P18146	BXGT008384	Early growth response protein 1	1958	reviewed	Nucleic acid binding
P20273	BXGT008557	B-cell receptor CD22	933	reviewed
P21359	BXGT008640	Neurofibromin	4763	reviewed	Enzyme modulator
P21802	BXGT008691	Fibroblast growth factor receptor 2	2263	reviewed	Kinase
P22681	BXGT008795	E3 ubiquitin-protein ligase CBL	867	reviewed	Enzyme
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P25440	BXGT009044	Bromodomain-containing protein 2	6046	reviewed	Epigenetic regulator
P26951	BXGT009147	Interleukin-3 receptor subunit alpha	3563	reviewed	Signaling
P31645	BXGT009558	Sodium-dependent serotonin transporter	6532	reviewed	Transporter
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35520	BXGT009842	Cystathionine beta-synthase	875	reviewed
P36888	BXGT009938	Receptor-type tyrosine-protein kinase FLT3	2322	reviewed	Kinase
P38936	BXGT010074	Cyclin-dependent kinase inhibitor 1	1026	reviewed
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P41143	BXGT010223	Delta-type opioid receptor	4985	reviewed	G-protein coupled receptor
P41182	BXGT010231	B-cell lymphoma 6 protein	604	reviewed
P41212	BXGT010235	Transcription factor ETV6	2120	reviewed	Transcription factor
P42224	BXGT010286	Signal transducer and activator of transcription 1-alpha/beta	6772	reviewed	Nucleic acid binding
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P43489	BXGT010394	Tumor necrosis factor receptor superfamily member 4	7293	reviewed
P46100	BXGT010508	Transcriptional regulator ATRX	546	reviewed
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P49792	BXGT010743	E3 SUMO-protein ligase RanBP2	5903	reviewed	Enzyme modulator
P51531	BXGT010851	Probable global transcription activator SNF2L2	6595	reviewed	Epigenetic regulator
P51692	BXGT010885	Signal transducer and activator of transcription 5B	6777	reviewed	Nucleic acid binding
P52952	BXGT010966	Homeobox protein Nkx-2.5	1482	reviewed	Transcription factor
P54136	BXGT011033	Arginine--tRNA ligase, cytoplasmic	5917	reviewed
P55157	BXGT011108	Microsomal triglyceride transfer protein large subunit	4547	reviewed	Transporter
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P60568	BXGT011315	Interleukin-2	3558	reviewed
P61769	BXGT011383	Beta-2-microglobulin	567	reviewed	Immune response
P78330	BXGT011833	Phosphoserine phosphatase	5723	reviewed	Enzyme
Q01196	BXGT012575	Runt-related transcription factor 1	861	reviewed	Transcription factor
Q01453	BXGT012588	Peripheral myelin protein 22	5376	reviewed	Cellular structure
Q03164	BXGT012700	Histone-lysine N-methyltransferase 2A	4297	reviewed
Q05513	BXGT012820	Protein kinase C zeta type	5590	reviewed	Kinase
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q06418	BXGT012875	Tyrosine-protein kinase receptor TYRO3	7301	reviewed	Kinase
Q13485	BXGT013363	Mothers against decapentaplegic homolog 4	4089	reviewed	Transcription factor
Q13951	BXGT013407	Core-binding factor subunit beta	865	reviewed
Q15078	BXGT013534	Cyclin-dependent kinase 5 activator 1	8851	reviewed	Enzyme modulator
Q15185	BXGT013549	Prostaglandin E synthase 3	10728	reviewed	Chaperone
Q15369	BXGT013560	Elongin-C	6921	reviewed	Enzyme modulator
Q15465	BXGT013573	Sonic hedgehog protein	6469	reviewed
Q6N021	BXGT016378	Methylcytosine dioxygenase TET2	54790	reviewed
Q6ZN17	BXGT016631	Protein lin-28 homolog B	389421	reviewed
Q92841	BXGT019383	Probable ATP-dependent RNA helicase DDX17	10521	reviewed
Q96GD0	BXGT019665	Pyridoxal phosphate phosphatase	57026	reviewed	Enzyme
Q99593	BXGT019939	T-box transcription factor TBX5	6910	reviewed	Transcription factor
Q9BS40	BXGT020121	Latexin	56925	reviewed
Q9UM73	BXGT021773	ALK tyrosine kinase receptor	238	reviewed	Kinase
Q9Y619	BXGT022316	Mitochondrial ornithine transporter 1	10166	reviewed	Transporter
P15509	BXGT022826	Granulocyte-macrophage colony-stimulating factor receptor subunit alpha	1438	reviewed	Signaling
Q96KP4	BXGT022829	Cytosolic non-specific dipeptidase	55748	reviewed	Enzyme
P43146	BXGT022852	Netrin receptor DCC	1630	reviewed
P35240	BXGT022927	Merlin	4771	reviewed
P16284	BXGT022972	Platelet endothelial cell adhesion molecule	5175	reviewed	Cell adhesion
P20138	BXGT023857	Myeloid cell surface antigen CD33	945	reviewed	Receptor
P29590	BXGT024350	Protein PML	5371	reviewed
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator
Q9P2E7	BXGT025815	Protocadherin-10	57575	reviewed
P62263	BXGT026033	40S ribosomal protein S14	6208	reviewed	Nucleic acid binding

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}