Showing entry for Beta-1 adrenergic receptor


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008380
Protein NameBeta-1 adrenergic receptor
Uniport IdP18090
GeneAdrb1
Gene Id24925
Domain7tm_1
Pfam PF00001  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway
Biological Process GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
Biological Process GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
Biological Process GO:0007568 aging
Biological Process GO:0006915 apoptotic process
Biological Process GO:0050873 brown fat cell differentiation
Biological Process GO:0002024 diet induced thermogenesis
Biological Process GO:0042596 fear response
Biological Process GO:0005980 glycogen catabolic process
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0031649 heat generation
Biological Process GO:0060080 inhibitory postsynaptic potential
Biological Process GO:0055088 lipid homeostasis
Biological Process GO:0007613 memory
Biological Process GO:0040015 negative regulation of multicellular organism growth
Biological Process GO:0045986 negative regulation of smooth muscle contraction
Biological Process GO:0035811 negative regulation of urine volume
Biological Process GO:0002025 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
Biological Process GO:0106071 positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
Biological Process GO:0045762 positive regulation of adenylate cyclase activity
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:1905665 positive regulation of calcium ion import across plasma membrane
Biological Process GO:2001259 positive regulation of cation channel activity
Biological Process GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development
Biological Process GO:0120162 positive regulation of cold-induced thermogenesis
Biological Process GO:0043547 positive regulation of GTPase activity
Biological Process GO:0010460 positive regulation of heart rate
Biological Process GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine
Biological Process GO:1900273 positive regulation of long-term synaptic potentiation
Biological Process GO:1900135 positive regulation of renin secretion into blood stream
Biological Process GO:0046878 positive regulation of saliva secretion
Biological Process GO:0003084 positive regulation of systemic arterial blood pressure
Biological Process GO:0001997 positive regulation of the force of heart contraction by epinephrine-norepinephrine
Biological Process GO:0003061 positive regulation of the force of heart contraction by norepinephrine
Biological Process GO:0033365 protein localization to organelle
Biological Process GO:0051924 regulation of calcium ion transport
Biological Process GO:0086004 regulation of cardiac muscle cell contraction
Biological Process GO:0045187 regulation of circadian sleep/wake cycle, sleep
Biological Process GO:0009409 response to cold
Biological Process GO:0007266 Rho protein signal transduction
Biological Process GO:0019233 sensory perception of pain
Biological Process GO:0042060 wound healing
molecular function GO:0031694 alpha-2A adrenergic receptor binding
molecular function GO:0004940 beta1-adrenergic receptor activity
molecular function GO:0035240 dopamine binding
molecular function GO:0008144 drug binding
molecular function GO:0051379 epinephrine binding
molecular function GO:0099579 G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0051380 norepinephrine binding
molecular function GO:0030165 PDZ domain binding
molecular function GO:0046982 protein heterodimerization activity
molecular function GO:0005088 Ras guanyl-nucleotide exchange factor activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005769 early endosome
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0016020 membrane
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
cellular component GO:0098794 postsynapse
cellular component GO:0098685 Schaffer collateral - CA1 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000538 (R)-Norepinephrine 169.18
BXGC0000982 L-Homocysteine 135.19
BXGC0005683 Quercetin 302.24
BXGC0005867 Serotonin 176.22
BXGC0005871 Dopamine 153.18
BXGC0005874 Racemethionine 149.21
BXGC0006183 L-Cystine 240.3
BXGC0007467 alpha-Terpineol 154.25
BXGC0017443 Phenylephrine 167.09
BXGC0018063 Alprenolol 249.17
BXGC0021893 Norepinephrine 169.07
BXGC0031384 Epinephrine 183.09
BXGC0038837 Pseudohypericin 520.08
BXGC0041240 Atenolol 266.16
BXGC0042222 Propranolol 259.16
BXGC0042462 Cysteine 121.02
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein