Showing entry for Amiloride-sensitive amine oxidase [copper-containing]


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008516
Protein NameAmiloride-sensitive amine oxidase [copper-containing]
Uniport IdP19801
GeneAOC1
Gene Id26
DomainCu_amine_oxid; Cu_amine_oxidN2; Cu_amine_oxidN3
Pfam PF01179   PF02727   PF02728  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.5 Amino acid metabolism hsa00330 Arginine and proline metabolism
1. Metabolism 1.5 Amino acid metabolism hsa00340 Histidine metabolism
1. Metabolism 1.5 Amino acid metabolism hsa00380 Tryptophan metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0009308 amine metabolic process
Biological Process GO:0097185 cellular response to azide
Biological Process GO:0071280 cellular response to copper ion
Biological Process GO:0035874 cellular response to copper ion starvation
Biological Process GO:0071504 cellular response to heparin
Biological Process GO:0071420 cellular response to histamine
Biological Process GO:0043312 neutrophil degranulation
Biological Process GO:0055114 oxidation-reduction process
Biological Process GO:0046677 response to antibiotic
Biological Process GO:0042493 response to drug
Biological Process GO:0006805 xenobiotic metabolic process
molecular function GO:0005509 calcium ion binding
molecular function GO:0005507 copper ion binding
molecular function GO:0052597 diamine oxidase activity
molecular function GO:0008144 drug binding
molecular function GO:0008201 heparin binding
molecular function GO:0052598 histamine oxidase activity
molecular function GO:0052599 methylputrescine oxidase activity
molecular function GO:0008131 primary amine oxidase activity
molecular function GO:0052600 propane-1,3-diamine oxidase activity
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0048038 quinone binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0005923 bicellular tight junction
cellular component GO:0070062 extracellular exosome
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
cellular component GO:0005777 peroxisome
cellular component GO:0005886 plasma membrane
cellular component GO:0035580 specific granule lumen
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-211859 Biological oxidations
R-HSA-211945 Phase I - Functionalization of compounds
R-HSA-6798695 Neutrophil degranulation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005890 BXGD000345 Body Height
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007286 BXGD000459 Carpal Tunnel Syndrome Nervous System Diseases; Wounds and Injuries
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0011853 BXGD000752 Diabetes Mellitus, Experimental Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013384 BXGD000826 Dyskinetic syndrome Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0014457 BXGD000915 Eosinophilia Hemic and Lymphatic Diseases
C0016470 BXGD001060 Food Allergy Immune System Diseases
C0018800 BXGD001225 Cardiomegaly Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0022661 BXGD001572 Kidney Failure, Chronic Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022735 BXGD001581 Klinefelter Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0023530 BXGD001683 Leukopenia Hemic and Lymphatic Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027947 BXGD002061 Neutropenia Hemic and Lymphatic Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0033860 BXGD002438 Psoriasis Skin and Connective Tissue Diseases
C0035455 BXGD002554 Rhinitis Infections; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0042834 BXGD003004 Vital capacity
C0149931 BXGD003388 Migraine Disorders Nervous System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0202236 BXGD004086 Triglycerides measurement
C0206651 BXGD004215 Clear Cell Sarcoma of Soft Tissue Neoplasms
C0206669 BXGD004229 Hepatocellular Adenoma Digestive System Diseases; Neoplasms
C0342190 BXGD007440 C-cell hyperplasia of thyroid Pathological Conditions, Signs and Symptoms; Endocrine System Diseases
C0392885 BXGD008071 High density lipoprotein measurement
C0406317 BXGD008334 Chronic small plaque psoriasis Skin and Connective Tissue Diseases
C0428472 BXGD008630 Serum HDL cholesterol measurement
C0432474 BXGD008793 Klinefelter's syndrome - male with more than two X chromosomes Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0578870 BXGD009553 Chronic idiopathic urticaria Skin and Connective Tissue Diseases; Immune System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306759 BXGD012374 Eosinophilic disorder Hemic and Lymphatic Diseases
C1383860 BXGD012935 Cardiac Hypertrophy Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1512409 BXGD013188 Hepatocarcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1833921 BXGD013946 Familial medullary thyroid carcinoma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Endocrine System Diseases
C1847540 BXGD014874 Azoospermia, Nonobstructive Male Urogenital Diseases
C1861821 BXGD016076 CATARACT, MARNER TYPE Eye Diseases
C1960398 BXGD016658 HER2-positive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C2363929 BXGD017118 Histamine intolerance
C2607914 BXGD017148 Allergic rhinitis (disorder) Respiratory Tract Diseases; Immune System Diseases; Otorhinolaryngologic Diseases
C2919945 BXGD017882 Cavernous Hemangioma of Brain Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C2985280 BXGD018223 Blood Protein Measurement
C4023106 BXGD021109 Obstructive azoospermia Male Urogenital Diseases
C4554344 BXGD023564 IgE-mediated food allergy Immune System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002586 Calcium 40.08
BXGC0005794 Benzylamine 107.15
BXGC0018397 beta-1,4-mannan 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein