Showing entry for Metabotropic glutamate receptor 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008861
Protein NameMetabotropic glutamate receptor 1
Uniport IdP23385
GeneGrm1
Gene Id24414
Domain7tm_3; ANF_receptor; GluR_Homer-bdg; NCD3G
Pfam PF00003   PF01094   PF10606   PF07562  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0000187 activation of MAPK activity
Biological Process GO:0000186 activation of MAPKK activity
Biological Process GO:0019722 calcium-mediated signaling
Biological Process GO:0071257 cellular response to electrical stimulus
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0007216 G protein-coupled glutamate receptor signaling pathway
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0007626 locomotory behavior
Biological Process GO:0051899 membrane depolarization
Biological Process GO:0007206 phospholipase C-activating G protein-coupled glutamate receptor signaling pathway
Biological Process GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
Biological Process GO:0014048 regulation of glutamate secretion
Biological Process GO:0043408 regulation of MAPK cascade
Biological Process GO:0051930 regulation of sensory perception of pain
Biological Process GO:0051966 regulation of synaptic transmission, glutamatergic
Biological Process GO:0019233 sensory perception of pain
Biological Process GO:0051932 synaptic transmission, GABAergic
molecular function GO:0030331 estrogen receptor binding
molecular function GO:0008066 glutamate receptor activity
molecular function GO:0098872 G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0099530 G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential
molecular function GO:0042802 identical protein binding
molecular function GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
molecular function GO:0001639 PLC activating G protein-coupled glutamate receptor activity
cellular component GO:0030424 axon
cellular component GO:0030425 dendrite
cellular component GO:0043197 dendritic spine
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0038037 G protein-coupled receptor dimeric complex
cellular component GO:0038038 G protein-coupled receptor homodimeric complex
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099061 integral component of postsynaptic density membrane
cellular component GO:0099055 integral component of postsynaptic membrane
cellular component GO:0043005 neuron projection
cellular component GO:0005634 nucleus
cellular component GO:0014069 postsynaptic density
cellular component GO:0098839 postsynaptic density membrane
cellular component GO:0042734 presynaptic membrane
cellular component GO:0098685 Schaffer collateral - CA1 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000264 L-2-Amino-4-methylenepentanedioic acid 159.14
BXGC0000651 Harmalan 184.24
BXGC0001545 Harmine 212.25
BXGC0001642 Tricholomic acid 160.13
BXGC0002588 Magnesium 24.31
BXGC0006162 L-Glutamic acid 147.13
BXGC0006163 Glutamic acid 147.13
BXGC0012332 Gadolinium 157.25
BXGC0023948 (S)-2-Aminoadipic Acid 161.07
BXGC0036441 Quisqualate 189.04
BXGC0036476 D-Glutamate 147.05
BXGC0046860 4-methylene-D-glutamic acid 159.05
BXGC0052372 (2S,4S)-4-Hydroxyglutamic Acid 163.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein