Showing entry for Metabotropic glutamate receptor 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009539
Protein NameMetabotropic glutamate receptor 2
Uniport IdP31421
GeneGrm2
Gene Id24415
Domain7tm_3; ANF_receptor; NCD3G
Pfam PF00003   PF01094   PF07562  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0090461 glutamate homeostasis
Biological Process GO:0014047 glutamate secretion
Biological Process GO:0007216 G protein-coupled glutamate receptor signaling pathway
Biological Process GO:0046928 regulation of neurotransmitter secretion
Biological Process GO:0051896 regulation of protein kinase B signaling
Biological Process GO:0051966 regulation of synaptic transmission, glutamatergic
molecular function GO:0005246 calcium channel regulator activity
molecular function GO:0008066 glutamate receptor activity
molecular function GO:0001641 group II metabotropic glutamate receptor activity
molecular function GO:0097110 scaffold protein binding
cellular component GO:0097449 astrocyte projection
cellular component GO:0030424 axon
cellular component GO:0030425 dendrite
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0043005 neuron projection
cellular component GO:0042734 presynaptic membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000264 L-2-Amino-4-methylenepentanedioic acid 159.14
BXGC0000651 Harmalan 184.24
BXGC0001545 Harmine 212.25
BXGC0001642 Tricholomic acid 160.13
BXGC0006162 L-Glutamic acid 147.13
BXGC0023948 (S)-2-Aminoadipic Acid 161.07
BXGC0036441 Quisqualate 189.04
BXGC0036476 D-Glutamate 147.05
BXGC0046860 4-methylene-D-glutamic acid 159.05
BXGC0052372 (2S,4S)-4-Hydroxyglutamic Acid 163.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein