Showing entry for cAMP-dependent protein kinase catalytic subunit PRKX


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010895
Protein NamecAMP-dependent protein kinase catalytic subunit PRKX
Uniport IdP51817
GenePRKX
Gene Id5613
DomainPkinase
Pfam PF00069  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0001525 angiogenesis
Biological Process GO:0007155 cell adhesion
Biological Process GO:0031589 cell-substrate adhesion
Biological Process GO:0043542 endothelial cell migration
Biological Process GO:0001935 endothelial cell proliferation
Biological Process GO:0060562 epithelial tube morphogenesis
Biological Process GO:0060993 kidney morphogenesis
Biological Process GO:0030099 myeloid cell differentiation
Biological Process GO:0018105 peptidyl-serine phosphorylation
Biological Process GO:0046777 protein autophosphorylation
Biological Process GO:0030155 regulation of cell adhesion
Biological Process GO:0030334 regulation of cell migration
Biological Process GO:2000696 regulation of epithelial cell differentiation involved in kidney development
Biological Process GO:0007165 signal transduction
molecular function GO:0005524 ATP binding
molecular function GO:0004691 cAMP-dependent protein kinase activity
cellular component GO:0005952 cAMP-dependent protein kinase complex
cellular component GO:0005737 cytoplasm
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-111885 Opioid Signalling
R-HSA-111931 PKA-mediated phosphorylation of CREB
R-HSA-111933 Calmodulin induced events
R-HSA-111996 Ca-dependent events
R-HSA-111997 CaM pathway
R-HSA-112040 G-protein mediated events
R-HSA-112043 PLC beta mediated events
R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission
R-HSA-112315 Transmission across Chemical Synapses
R-HSA-112316 Neuronal System
R-HSA-1489509 DAG and IP3 signaling
R-HSA-162582 Signal Transduction
R-HSA-1643685 Disease
R-HSA-372790 Signaling by GPCR
R-HSA-388396 GPCR downstream signalling
R-HSA-418594 G alpha (i) signalling events
R-HSA-438064 Post NMDA receptor activation events
R-HSA-442720 CREB1 phosphorylation through the activation of Adenylate Cyclase
R-HSA-442755 Activation of NMDA receptors and postsynaptic events
R-HSA-5663205 Infectious disease
R-HSA-9006925 Intracellular signaling by second messengers
R-HSA-9658195 Leishmania infection
R-HSA-9660821 ADORA2B mediated anti-inflammatory cytokines production
R-HSA-9662851 Anti-inflammatory response favouring Leishmania parasite infection
R-HSA-9664323 FCGR3A-mediated IL10 synthesis
R-HSA-9664433 Leishmania parasite growth and survival
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0085413 BXGD003171 Polycystic Kidney, Autosomal Dominant Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0202230 BXGD004084 Thyroid stimulating hormone measurement
C0432470 BXGD008792 46, XY female Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0432475 BXGD008794 XX males Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1378703 BXGD012933 Renal carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0012352 Chelerythrine 348.12
BXGC0013109 4-[2-(3,5-Dihydroxyphenyl)Ethenyl]Benzene-1,2-Diol 244.07
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein