Showing entry for 4-[2-(3,5-Dihydroxyphenyl)Ethenyl]Benzene-1,2-Diol


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0013109
Compound Name4-[2-(3,5-Dihydroxyphenyl)Ethenyl]Benzene-1,2-Diol
Structure
FormulaC14H12O4
InchiKeyCDRPUGZCRXZLFL-UHFFFAOYSA-N
SMILESOc1cc(C=Cc2ccc(c(c2)O)O)cc(c1)O
InchiInChI=1S/C14H12O4/c15-11-5-10(6-12(16)8-11)2-1-9-3-4-13(17)14(18)7-9/h1-8,15-18H
IUPAC4-[2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2-diol
Molecular Weight244.07
Pubchem Id4813
Chembl IdCHEMBL1972346
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
CHEMBL CHEMBL1972346
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q14680 BXGT013499 Maternal embryonic leucine zipper kinase reviewed Kinase MELK Ki '=' 79 nM
Q9UM73 BXGT021773 ALK tyrosine kinase receptor reviewed Kinase ALK Ki '=' 251 nM
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS reviewed Kinase ROS1 Ki '=' 794 nM
Q8IU85 BXGT018333 Calcium/calmodulin-dependent protein kinase type 1D reviewed Kinase CAMK1D Ki '=' 501 nM
Q13464 BXGT013357 Rho-associated protein kinase 1 reviewed Kinase ROCK1 Ki '=' 2511 nM
P08631 BXGT006801 Tyrosine-protein kinase HCK reviewed Kinase HCK Ki '=' 398 nM
P49336 BXGT010697 Cyclin-dependent kinase 8 reviewed Kinase CDK8 Ki '=' 251 nM
Q5S007 BXGT015650 Leucine-rich repeat serine/threonine-protein kinase 2 reviewed Kinase LRRK2 Ki '=' 501 nM
P29376 BXGT009339 Leukocyte tyrosine kinase receptor reviewed Kinase LTK Ki '=' 316 nM
P48729 BXGT010655 Casein kinase I isoform alpha reviewed Kinase CSNK1A1 Ki '=' 316 nM
Q7L7X3 BXGT016997 Serine/threonine-protein kinase TAO1 reviewed Kinase TAOK1 Ki '=' 1000 nM
P49840 BXGT010749 Glycogen synthase kinase-3 alpha reviewed Kinase GSK3A Ki '=' 3162 nM
P17612 BXGT008322 cAMP-dependent protein kinase catalytic subunit alpha reviewed Kinase PRKACA Ki '=' 1584 nM
P51817 BXGT010895 cAMP-dependent protein kinase catalytic subunit PRKX reviewed Kinase PRKX Ki '=' 630 nM
Q02750 BXGT012662 Dual specificity mitogen-activated protein kinase kinase 1 reviewed Kinase MAP2K1 Ki '>' 3162 nM
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 reviewed Kinase KDR Ki '>' 2511 nM
Q96L34 BXGT019689 MAP/microtubule affinity-regulating kinase 4 reviewed Kinase MARK4 Ki '=' 50 nM
Q96RR4 BXGT019734 Calcium/calmodulin-dependent protein kinase kinase 2 reviewed Kinase CAMKK2 Ki '=' 63 nM
Q04759 BXGT012781 Protein kinase C theta type reviewed Kinase PRKCQ Ki '=' 794 nM
Q9HBY8 BXGT020524 Serine/threonine-protein kinase Sgk2 reviewed Kinase SGK2 Ki '=' 316 nM
P07333 BXGT006602 Macrophage colony-stimulating factor 1 receptor reviewed Kinase CSF1R Ki '>' 2511 nM
Q05397 BXGT012815 Focal adhesion kinase 1 reviewed Kinase PTK2 Ki '=' 794 nM
P51812 BXGT010893 Ribosomal protein S6 kinase alpha-3 reviewed Kinase RPS6KA3 Ki '=' 1584 nM
P52333 BXGT010928 Tyrosine-protein kinase JAK3 reviewed Kinase JAK3 Ki '=' 1000 nM
Q13627 BXGT013385 Dual specificity tyrosine-phosphorylation-regulated kinase 1A reviewed Kinase DYRK1A Ki '=' 31 nM
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 reviewed Kinase FLT1 Ki '=' 501 nM
P36888 BXGT009938 Receptor-type tyrosine-protein kinase FLT3 reviewed Kinase FLT3 Ki '>' 1995 nM
Q9UQM7 BXGT021814 Calcium/calmodulin-dependent protein kinase type II subunit alpha reviewed Kinase CAMK2A Ki '=' 794 nM
Q9Y463 BXGT022269 Dual specificity tyrosine-phosphorylation-regulated kinase 1B reviewed Kinase DYRK1B Ki '=' 100 nM
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK Ki '>' 5011 nM
Q9HCT0 BXGT020538 Fibroblast growth factor 22 reviewed Signaling FGF22 AbsAC1 '=' 11 uM
P11309 BXGT007685 Serine/threonine-protein kinase pim-1 reviewed Kinase PIM1 Ki '=' 2511 nM
O75116 BXGT005100 Rho-associated protein kinase 2 reviewed Kinase ROCK2 Ki '=' 125 nM
O95819 BXGT005398 Mitogen-activated protein kinase kinase kinase kinase 4 reviewed Kinase MAP4K4 Ki '=' 501 nM
Q14164 BXGT013451 Inhibitor of nuclear factor kappa-B kinase subunit epsilon reviewed Kinase IKBKE Ki '=' 398 nM
P49760 BXGT010735 Dual specificity protein kinase CLK2 reviewed Kinase CLK2 Ki '=' 501 nM
Q02779 BXGT012670 Mitogen-activated protein kinase kinase kinase 10 reviewed Kinase MAP3K10 Ki '=' 100 nM
Q9UHD2 BXGT021697 Serine/threonine-protein kinase TBK1 reviewed Kinase TBK1 Ki '=' 630 nM
P11362 BXGT007693 Fibroblast growth factor receptor 1 reviewed Kinase FGFR1 Ki '=' 630 nM
P55210 BXGT011110 Caspase-7 reviewed Enzyme CASP7 AC50 '>' 70000 nM
P34947 BXGT009774 G protein-coupled receptor kinase 5 reviewed Kinase GRK5 Ki '=' 501 nM
Q04771 BXGT012783 Activin receptor type-1 reviewed Kinase ACVR1 Ki '=' 501 nM
Q13188 BXGT013324 Serine/threonine-protein kinase 3 reviewed Kinase STK3 Ki '=' 630 nM
P49841 BXGT010750 Glycogen synthase kinase-3 beta reviewed Kinase GSK3B Ki '=' 1000 nM
P16234 BXGT008209 Platelet-derived growth factor receptor alpha reviewed Kinase PDGFRA Ki '=' 1000 nM
P27448 BXGT009183 MAP/microtubule affinity-regulating kinase 3 reviewed Kinase MARK3 Ki '=' 251 nM
Q14790 BXGT013505 Caspase-8 reviewed Enzyme CASP8 AC50 '>' 70000 nM
P53779 BXGT011014 Mitogen-activated protein kinase 10 reviewed Kinase MAPK10 Ki '=' 50 nM
Q9H0K1 BXGT020438 Serine/threonine-protein kinase SIK2 reviewed Kinase SIK2 Ki '=' 100 nM
O60674 BXGT004892 Tyrosine-protein kinase JAK2 reviewed Kinase JAK2 Ki '=' 794 nM
P07949 BXGT006703 Proto-oncogene tyrosine-protein kinase receptor Ret reviewed Kinase RET Ki '=' 398 nM
Q07912 BXGT012947 Activated CDC42 kinase 1 reviewed Kinase TNK2 Ki '=' 630 nM
Q06418 BXGT012875 Tyrosine-protein kinase receptor TYRO3 reviewed Kinase TYRO3 Ki '=' 79 nM
P55212 BXGT011112 Caspase-6 reviewed Enzyme CASP6 AC50 '=' 1200 nM
Q06187 BXGT012860 Tyrosine-protein kinase BTK reviewed Kinase BTK Ki '=' 630 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF01082 Hemsleya graciliflora Hemsleya graciliflora Medicinal Plant
BXGF01126 Polygonum cuspidatum Polygonum cuspidatum Medicinal Plant
BXGF03479 Bombax ceiba Bombax ceiba Medicinal Plant
BXGF04450 Senna lindheimeriana Senna lindheimeriana Others
BXGF05488 Endiandra xanthocarpa Endiandra xanthocarpa Others
BXGF06176 Helichrysum subulifolium Helichrysum subulifolium Others
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease