Showing entry for Neuropeptide Y receptor type 5


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013596
Protein NameNeuropeptide Y receptor type 5
Uniport IdQ15761
GeneNPY5R
Gene Id4889
Domain7tm_1
Pfam PF00001  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007568 aging
Biological Process GO:0003214 cardiac left ventricle morphogenesis
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0042755 eating behavior
Biological Process GO:0060112 generation of ovulation cycle rhythm
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0014050 negative regulation of glutamate secretion
Biological Process GO:0032229 negative regulation of synaptic transmission, GABAergic
Biological Process GO:0003151 outflow tract morphogenesis
Biological Process GO:0002675 positive regulation of acute inflammatory response
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0048661 positive regulation of smooth muscle cell proliferation
molecular function GO:0004983 neuropeptide Y receptor activity
molecular function GO:0001602 pancreatic polypeptide receptor activity
molecular function GO:0001601 peptide YY receptor activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0016020 membrane
cellular component GO:0043005 neuron projection
cellular component GO:0005886 plasma membrane
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-372790 Signaling by GPCR
R-HSA-373076 Class A/1 (Rhodopsin-like receptors)
R-HSA-375276 Peptide ligand-binding receptors
R-HSA-388396 GPCR downstream signalling
R-HSA-418594 G alpha (i) signalling events
R-HSA-500792 GPCR ligand binding
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007103 BXGD000426 Malignant neoplasm of endometrium Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0013473 BXGD000845 Eating Disorders Mental Disorders
C0014553 BXGD000931 Absence Epilepsy Nervous System Diseases
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020459 BXGD001394 Hyperinsulinism Nutritional and Metabolic Diseases
C0021368 BXGD001502 Inflammation Pathological Conditions, Signs and Symptoms
C0023518 BXGD001677 Leukocytosis Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0030319 BXGD002208 Panic Disorder Mental Disorders
C0033375 BXGD002405 Prolactinoma Neoplasms; Nervous System Diseases; Endocrine System Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0085762 BXGD003251 Alcohol abuse Chemically-Induced Disorders; Mental Disorders
C0236663 BXGD004817 Alcohol withdrawal syndrome Chemically-Induced Disorders; Mental Disorders
C0242339 BXGD005150 Dyslipidemias Nutritional and Metabolic Diseases
C0270824 BXGD006113 Visual seizure Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0948480 BXGD011540 Coronary Restenosis Cardiovascular Diseases
C1292778 BXGD012237 Chronic myeloproliferative disorder Neoplasms; Hemic and Lymphatic Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1334804 BXGD012740 Motor Manifestations Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0030248 2-(4-Hydroxyphenyl)Chromen-4-One 238.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein