protein

Showing entry for Canalicular multispecific organic anion transporter 1

General Target Information
BXGT Id	BXGT016061
Protein Name	Canalicular multispecific organic anion transporter 1
Uniport Id	Q63120
Gene	Abcc2
Gene Id	25303
Domain	ABC_membrane; ABC_tran
Pfam	PF00664 PF00005
Organism	Rattus norvegicus (Rat)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0016999	antibiotic metabolic process
Biological Process	GO:1901086	benzylpenicillin metabolic process
Biological Process	GO:0015721	bile acid and bile salt transport
Biological Process	GO:0038183	bile acid signaling pathway
Biological Process	GO:0015722	canalicular bile acid transport
Biological Process	GO:0030644	cellular chloride ion homeostasis
Biological Process	GO:0071549	cellular response to dexamethasone stimulus
Biological Process	GO:0035690	cellular response to drug
Biological Process	GO:0071347	cellular response to interleukin-1
Biological Process	GO:0071354	cellular response to interleukin-6
Biological Process	GO:0071222	cellular response to lipopolysaccharide
Biological Process	GO:0071356	cellular response to tumor necrosis factor
Biological Process	GO:0050787	detoxification of mercury ion
Biological Process	GO:0046618	drug export
Biological Process	GO:0006855	drug transmembrane transport
Biological Process	GO:0007565	female pregnancy
Biological Process	GO:0006954	inflammatory response
Biological Process	GO:0071716	leukotriene transport
Biological Process	GO:0015694	mercury ion transport
Biological Process	GO:0010629	negative regulation of gene expression
Biological Process	GO:0015711	organic anion transport
Biological Process	GO:0015732	prostaglandin transport
Biological Process	GO:0120188	regulation of bile acid secretion
Biological Process	GO:0010468	regulation of gene expression
Biological Process	GO:1904486	response to 17alpha-ethynylestradiol
Biological Process	GO:0097327	response to antineoplastic agent
Biological Process	GO:0046685	response to arsenic-containing substance
Biological Process	GO:0042493	response to drug
Biological Process	GO:0032355	response to estradiol
Biological Process	GO:0043627	response to estrogen
Biological Process	GO:0033762	response to glucagon
Biological Process	GO:0009408	response to heat
Biological Process	GO:0032496	response to lipopolysaccharide
Biological Process	GO:0031427	response to methotrexate
Biological Process	GO:0006979	response to oxidative stress
Biological Process	GO:0048545	response to steroid hormone
Biological Process	GO:0070327	thyroid hormone transport
Biological Process	GO:0070633	transepithelial transport
Biological Process	GO:0055085	transmembrane transport
Biological Process	GO:0042178	xenobiotic catabolic process
Biological Process	GO:1990961	xenobiotic detoxification by transmembrane export across the plasma membrane
Biological Process	GO:1990962	xenobiotic transport across blood-brain barrier
molecular function	GO:0016887	ATPase activity
molecular function	GO:0042626	ATPase-coupled transmembrane transporter activity
molecular function	GO:0008559	ATPase-coupled xenobiotic transmembrane transporter activity
molecular function	GO:0005524	ATP binding
molecular function	GO:0008514	organic anion transmembrane transporter activity
molecular function	GO:0019904	protein domain specific binding
molecular function	GO:0042910	xenobiotic transmembrane transporter activity
cellular component	GO:0016324	apical plasma membrane
cellular component	GO:0031526	brush border membrane
cellular component	GO:0009986	cell surface
cellular component	GO:0005887	integral component of plasma membrane
cellular component	GO:0046581	intercellular canaliculus
cellular component	GO:0016020	membrane

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0000563	1H-Indole-3-methanol		147.17
BXGC0002619	Di-2-propenyl-sulfane		114.21
BXGC0002627	17alpha-ethynylestradiol		296.4
BXGC0003611	Latex		416.57
BXGC0006216	Sulforaphane		177.29
BXGC0012352	Chelerythrine		348.12
BXGC0013452	Dioctyl phthalate		390.28
BXGC0016671	Leucovorin		473.17
BXGC0019003	Levomefolic Acid		459.19
BXGC0024988	Nifedipine		346.12
BXGC0025658	Vinblastine		810.42
BXGC0026595	Glycyrrhizin		822.4
BXGC0027374	Glyburide		493.14
BXGC0031558	Baicalin		446.08
BXGC0033776	Cycloheximide		281.16
BXGC0034768	Vincristine		824.4

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}