Showing entry for Latex


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0003611
Compound NameLatex
Structure
FormulaC24H32O4S
InchiKeyLXMSZDCAJNLERA-ZHYRCANASA-N
SMILES[H][C@@]12CC[C@@]3(CCC(=O)O3)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])[C@@]([H])(CC2=CC(=O)CC[C@]12C)SC(C)=O
InchiInChI=1S/C24H32O4S/c1-14(25)29-19-13-15-12-16(26)4-8-22(15,2)17-5-9-23(3)18(21(17)19)6-10-24(23)11-7-20(27)28-24/h12,17-19,21H,4-11,13H2,1-3H3/t17-,18-,19+,21+,22-,23-,24+/m0/s1
IUPAC(1'S,2R,2'R,9'R,10'R,11'S,15'S)-9'-(acetylsulfanyl)-2',15'-dimethylspiro[oxolane-2,14'-tetracyclo[8.7.0.02,?.011,1?]heptadecan]-6'-ene-5,5'-dione
Molecular Weight416.57
Pubchem Id5833
Chembl IdCHEMBL1393
Targets of Information Source
DrugBank DB00421
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P08235 BXGT006751 Mineralocorticoid receptor reviewed Nuclear receptor NR3C2 approved antagonist
P10275 BXGT007552 Androgen receptor reviewed Nuclear receptor AR approved antagonist
P06401 BXGT006436 Progesterone receptor reviewed Nuclear receptor PGR approved agonist
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 approved antagonist
P19099 BXGT008456 Cytochrome P450 11B2, mitochondrial reviewed - CYP11B2 approved antagonist
P05093 BXGT006313 Steroid 17-alpha-hydroxylase/17,20 lyase reviewed - CYP17A1 approved antagonist
P18405 BXGT008400 3-oxo-5-alpha-steroid 4-dehydrogenase 1 reviewed Enzyme SRD5A1 approved -
P31213 BXGT009515 3-oxo-5-alpha-steroid 4-dehydrogenase 2 reviewed Enzyme SRD5A2 approved -
Q9H8P0 BXGT020497 Polyprenol reductase reviewed - SRD5A3 approved antagonist
P04278 BXGT006182 Sex hormone-binding globulin reviewed - SHBG approved binder
Q06432 BXGT012876 Voltage-dependent calcium channel gamma-1 subunit reviewed Ion channel CACNG1 approved -
Q9Y698 BXGT022323 Voltage-dependent calcium channel gamma-2 subunit reviewed Ion channel CACNG2 approved -
O60359 BXGT022652 Voltage-dependent calcium channel gamma-3 subunit reviewed Ion channel CACNG3 approved -
Q9UBN1 BXGT022653 Voltage-dependent calcium channel gamma-4 subunit reviewed Ion channel CACNG4 approved -
Q9UF02 BXGT022654 Voltage-dependent calcium channel gamma-5 subunit reviewed Ion channel CACNG5 approved -
Q9BXT2 BXGT022655 Voltage-dependent calcium channel gamma-6 subunit reviewed Ion channel CACNG6 approved -
P62955 BXGT022656 Voltage-dependent calcium channel gamma-7 subunit reviewed Ion channel CACNG7 approved -
Q8WXS5 BXGT022657 Voltage-dependent calcium channel gamma-8 subunit reviewed Ion channel CACNG8 approved -
P54289 BXGT011040 Voltage-dependent calcium channel subunit alpha-2/delta-1 reviewed Ion channel CACNA2D1 approved -
Q9NY47 BXGT021249 Voltage-dependent calcium channel subunit alpha-2/delta-2 reviewed Ion channel CACNA2D2 approved -
Q8IZS8 BXGT018372 Voltage-dependent calcium channel subunit alpha-2/delta-3 reviewed Ion channel CACNA2D3 approved -
Q7Z3S7 BXGT022658 Voltage-dependent calcium channel subunit alpha-2/delta-4 reviewed Ion channel CACNA2D4 approved -
Q13936 BXGT013404 Voltage-dependent L-type calcium channel subunit alpha-1C reviewed Ion channel CACNA1C approved -
Q01668 BXGT012605 Voltage-dependent L-type calcium channel subunit alpha-1D reviewed Ion channel CACNA1D approved -
O60840 BXGT004901 Voltage-dependent L-type calcium channel subunit alpha-1F reviewed Ion channel CACNA1F approved -
Q13698 BXGT013392 Voltage-dependent L-type calcium channel subunit alpha-1S reviewed Ion channel CACNA1S approved -
Q02641 BXGT012659 Voltage-dependent L-type calcium channel subunit beta-1 reviewed Ion channel CACNB1 approved -
Q08289 BXGT012979 Voltage-dependent L-type calcium channel subunit beta-2 reviewed Ion channel CACNB2 approved -
P54284 BXGT011039 Voltage-dependent L-type calcium channel subunit beta-3 reviewed Ion channel CACNB3 approved -
O00305 BXGT003907 Voltage-dependent L-type calcium channel subunit beta-4 reviewed Ion channel CACNB4 approved -
Q00975 BXGT012558 Voltage-dependent N-type calcium channel subunit alpha-1B reviewed Ion channel CACNA1B approved -
O00555 BXGT003936 Voltage-dependent P/Q-type calcium channel subunit alpha-1A reviewed Ion channel CACNA1A approved -
Q15878 BXGT022659 Voltage-dependent R-type calcium channel subunit alpha-1E reviewed Ion channel CACNA1E approved -
O43497 BXGT004596 Voltage-dependent T-type calcium channel subunit alpha-1G reviewed Ion channel CACNA1G approved -
O95180 BXGT005358 Voltage-dependent T-type calcium channel subunit alpha-1H reviewed Ion channel CACNA1H approved -
Q9P0X4 BXGT021293 Voltage-dependent T-type calcium channel subunit alpha-1I reviewed Ion channel CACNA1I approved inhibitor
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 reviewed Nuclear receptor NR1I2 approved -
PDB SNL
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P08235 BXGT006751 Mineralocorticoid receptor reviewed NR3C2 Nuclear receptor - - - -
P08235 BXGT006751 Mineralocorticoid receptor reviewed NR3C2 Nuclear receptor - 49 - -
Binding DB 50228080
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT007923 Cystic fibrosis transmembrane conductance regulator reviewed Ion channel CFTR - - - >50000
reviewed BXGT006751 Mineralocorticoid receptor reviewed Nuclear receptor NR3C2 - 11 - -
reviewed BXGT006436 Progesterone receptor reviewed Nuclear receptor PGR - 1400 - -
reviewed BXGT006751 Mineralocorticoid receptor reviewed Nuclear receptor NR3C2 - 60 - -
reviewed BXGT006751 Mineralocorticoid receptor reviewed Nuclear receptor NR3C2 - 49 - -
reviewed BXGT007552 Androgen receptor reviewed Nuclear receptor AR - 120 - -
reviewed BXGT006436 Progesterone receptor reviewed Nuclear receptor PGR - 650 - -
reviewed BXGT007552 Androgen receptor reviewed Nuclear receptor AR - 670 - -
reviewed BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 - >20000 - -
reviewed BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 >1100 - - -
reviewed BXGT007552 Androgen receptor reviewed Nuclear receptor AR 39.4 - - -
reviewed BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 32.6 - - -
reviewed BXGT006436 Progesterone receptor reviewed Nuclear receptor PGR 399.7 - - -
reviewed BXGT006751 Mineralocorticoid receptor reviewed Nuclear receptor NR3C2 2.323 - - -
reviewed BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 - 1400 - -
reviewed BXGT007552 Androgen receptor reviewed Nuclear receptor AR - 523 - -
reviewed BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 - 6920 - -
reviewed BXGT006436 Progesterone receptor reviewed Nuclear receptor PGR - >10000 - -
reviewed BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 - 5702 - -
reviewed BXGT008096 Androgen receptor reviewed Ar - 676.08 - -
reviewed BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 - 23600 - -
reviewed BXGT019660 Multidrug and toxin extrusion protein 1 reviewed Transporter SLC47A1 - 18600 - -
reviewed BXGT007552 Androgen receptor reviewed Nuclear receptor AR - - - >20000
reviewed BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 - 4100 - -
reviewed BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 - - - >20000
reviewed BXGT006436 Progesterone receptor reviewed Nuclear receptor PGR - 4000 - -
reviewed BXGT006436 Progesterone receptor reviewed Nuclear receptor PGR - - - >20000
CHEMBL CHEMBL1393
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P49146 BXGT010681 Neuropeptide Y receptor type 2 reviewed G-protein coupled receptor NPY2R IC50 - - -
P30988 BXGT009491 Calcitonin receptor reviewed G-protein coupled receptor CALCR IC50 - - -
P22199 BXGT008741 Mineralocorticoid receptor reviewed - Nr3c2 RBA '=' 3 %
P22199 BXGT008741 Mineralocorticoid receptor reviewed - Nr3c2 Relative potency '=' 1 -
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR Ki - - -
P28564 BXGT009272 5-hydroxytryptamine receptor 1B reviewed - Htr1b Ki - - -
P06186 BXGT006419 Progesterone receptor reviewed - PGR Competition factor '=' 21 -
P06401 BXGT006436 Progesterone receptor reviewed Nuclear receptor PGR EC50 '>' 20000 nM
P22199 BXGT008741 Mineralocorticoid receptor reviewed - Nr3c2 Relative potency '=' 100 -
P15207 BXGT008096 Androgen receptor reviewed - Ar Tp control '=' 73 %
P15207 BXGT008096 Androgen receptor reviewed - Ar Relative potency '=' 1 -
P15207 BXGT008096 Androgen receptor reviewed - Ar Tp control '=' 91 %
P06186 BXGT006419 Progesterone receptor reviewed - PGR McPhail index '=' 1 -
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 reviewed Transcription factor SMAD3 Potency - 35481 nM
P08235 BXGT006751 Mineralocorticoid receptor reviewed Nuclear receptor NR3C2 Kb '=' 17 nM
P43220 BXGT010367 Glucagon-like peptide 1 receptor reviewed G-protein coupled receptor GLP1R Potency - 10000 nM
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 Ki - - -
P11473 BXGT007709 Vitamin D3 receptor reviewed Nuclear receptor VDR Potency - 17782 nM
P10275 BXGT007552 Androgen receptor reviewed Nuclear receptor AR Potency - 63 nM
P15207 BXGT008096 Androgen receptor reviewed - Ar RBA '=' 2 %
P32245 BXGT009614 Melanocortin receptor 4 reviewed G-protein coupled receptor MC4R IC50 - - -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 - - -
P08235 BXGT006751 Mineralocorticoid receptor reviewed Nuclear receptor NR3C2 IC50 '=' 13 nM
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 IC50 - - -
P29466 BXGT009349 Caspase-1 reviewed Enzyme CASP1 IC50 - - -
Q08209 BXGT012968 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform reviewed - PPP3CA IC50 - - -
P21554 BXGT008662 Cannabinoid receptor 1 reviewed G-protein coupled receptor CNR1 Ki - - -
P51679 BXGT010877 C-C chemokine receptor type 4 reviewed G-protein coupled receptor CCR4 Ki - - -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 Ki - - -
P12530 BXGT007827 Arachidonate 15-lipoxygenase reviewed - ALOX15 IC50 - - -
P12530 BXGT007827 Arachidonate 15-lipoxygenase reviewed - ALOX15 Ki - - -
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 IC50 - - -
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 IC50 - - -
P25929 BXGT009078 Neuropeptide Y receptor type 1 reviewed G-protein coupled receptor NPY1R IC50 - - -
P25929 BXGT009078 Neuropeptide Y receptor type 1 reviewed G-protein coupled receptor NPY1R Ki - - -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki - - -
P10275 BXGT007552 Androgen receptor reviewed Nuclear receptor AR IC50 '=' 120 nM
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 Inhibition '=' 103 %
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 IC50 - - -
P05181 BXGT006337 Cytochrome P450 2E1 reviewed - CYP2E1 IC50 - - -
P14416 BXGT008011 D(2) dopamine receptor reviewed G-protein coupled receptor DRD2 IC50 - - -
P35462 BXGT009835 D(3) dopamine receptor reviewed G-protein coupled receptor DRD3 Ki - - -
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 IC50 - - -
P20781 BXGT008598 Glycine receptor subunit beta reviewed - Glrb IC50 - - -
P07727 BXGT006662 Glycine receptor subunit alpha-1 reviewed - Glra1 IC50 - - -
P24524 BXGT008974 Glycine receptor subunit alpha-3 reviewed - Glra3 IC50 - - -
P22771 BXGT008806 Glycine receptor subunit alpha-2 reviewed - Glra2 IC50 - - -
P15127 BXGT008085 Insulin receptor reviewed - Insr Ki - - -
P41968 BXGT010275 Melanocortin receptor 3 reviewed G-protein coupled receptor MC3R IC50 - - -
P32245 BXGT009614 Melanocortin receptor 4 reviewed G-protein coupled receptor MC4R Ki - - -
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 IC50 - - -
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 IC50 - - -
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 Ki - - -
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 IC50 - - -
P30988 BXGT009491 Calcitonin receptor reviewed G-protein coupled receptor CALCR Ki - - -
P19327 BXGT008472 5-hydroxytryptamine receptor 1A reviewed - Htr1a IC50 - - -
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 Ki - - -
Q690N0 BXGT016199 Progesterone receptor unreviewed - PGR IC50 '=' 1665 nM
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 IC50 - - -
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C reviewed Enzyme PTPRC Ki - - -
P28564 BXGT009272 5-hydroxytryptamine receptor 1B reviewed - Htr1b IC50 - - -
P18089 BXGT008379 Alpha-2B adrenergic receptor reviewed G-protein coupled receptor ADRA2B Ki - - -
Q96FL8 BXGT019660 Multidrug and toxin extrusion protein 1 reviewed Transporter SLC47A1 Inhibition '=' 27 %
P37288 BXGT009977 Vasopressin V1a receptor reviewed G-protein coupled receptor AVPR1A Ki - - -
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 Ki - - -
P32241 BXGT009613 Vasoactive intestinal polypeptide receptor 1 reviewed G-protein coupled receptor VIPR1 Ki - - -
P15207 BXGT008096 Androgen receptor reviewed - Ar Tp control '=' 138 %
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 RBA '<' 0 %
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 IC50 - - -
P14780 BXGT008053 Matrix metalloproteinase-9 reviewed Enzyme MMP9 Ki - - -
P06241 BXGT006429 Tyrosine-protein kinase Fyn reviewed Kinase FYN IC50 - - -
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 reviewed Kinase FLT1 IC50 - - -
P15207 BXGT008096 Androgen receptor reviewed - Ar Organ weight '=' 23 mg
P06186 BXGT006419 Progesterone receptor reviewed - PGR McPhail index '=' 1 -
P15207 BXGT008096 Androgen receptor reviewed - Ar RBA '=' 4 %
P12822 BXGT007850 Angiotensin-converting enzyme reviewed - ACE Ki - - -
P08311 BXGT006762 Cathepsin G reviewed Enzyme CTSG Ki - - -
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE Ki - - -
P50406 BXGT010796 5-hydroxytryptamine receptor 6 reviewed G-protein coupled receptor HTR6 IC50 - - -
P50406 BXGT010796 5-hydroxytryptamine receptor 6 reviewed G-protein coupled receptor HTR6 Ki - - -
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 Ki - - -
P25101 BXGT009018 Endothelin-1 receptor reviewed G-protein coupled receptor EDNRA Ki - - -
P21554 BXGT008662 Cannabinoid receptor 1 reviewed G-protein coupled receptor CNR1 IC50 - - -
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase reviewed - HMGCR IC50 - - -
P21397 BXGT008644 Amine oxidase [flavin-containing] A reviewed - MAOA IC50 - - -
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 Ki - - -
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 IC50 '=' 6920 nM
P37288 BXGT009977 Vasopressin V1a receptor reviewed G-protein coupled receptor AVPR1A IC50 - - -
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 EC50 '>' 20000 nM
P15207 BXGT008096 Androgen receptor reviewed - Ar Tp control '=' 82 %
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic reviewed - IDH1 Potency - 18356 nM
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 Potency - 11220 nM
P22199 BXGT008741 Mineralocorticoid receptor reviewed - Nr3c2 Activity - - -
P08588 BXGT006795 Beta-1 adrenergic receptor reviewed G-protein coupled receptor ADRB1 IC50 - - -
P07943 BXGT006700 Aldo-keto reductase family 1 member B1 reviewed - Akr1b1 Ki - - -
P15207 BXGT008096 Androgen receptor reviewed - Ar Ratio '=' 8 -
P10275 BXGT007552 Androgen receptor reviewed Nuclear receptor AR Ki '=' 39 nM
P06186 BXGT006419 Progesterone receptor reviewed - PGR McPhail index '=' 2 -
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma reviewed Nuclear receptor PPARG Potency - 39810 nM
P56937 BXGT011205 3-keto-steroid reductase reviewed - HSD17B7 Inhibition '=' 7 %
P15207 BXGT008096 Androgen receptor reviewed - Ar RBA '=' 3 %
P15127 BXGT008085 Insulin receptor reviewed - Insr IC50 - - -
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 Ki - - -
P30411 BXGT009424 B2 bradykinin receptor reviewed G-protein coupled receptor BDKRB2 IC50 - - -
P25024 BXGT009005 C-X-C chemokine receptor type 1 reviewed G-protein coupled receptor CXCR1 Ki - - -
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 IC50 - - -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 IC50 - - -
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Ki - - -
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 Ki - - -
P25021 BXGT009004 Histamine H2 receptor reviewed G-protein coupled receptor HRH2 IC50 - - -
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE IC50 - - -
P03956 BXGT006120 Interstitial collagenase reviewed Enzyme MMP1 Ki - - -
P06241 BXGT006429 Tyrosine-protein kinase Fyn reviewed Kinase FYN Ki - - -
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK Ki - - -
P28335 BXGT009255 5-hydroxytryptamine receptor 2C reviewed G-protein coupled receptor HTR2C Ki - - -
P15207 BXGT008096 Androgen receptor reviewed - Ar IC50 '=' 135 nM
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE Ki - - -
P29274 BXGT009327 Adenosine receptor A2a reviewed G-protein coupled receptor ADORA2A Ki - - -
P25100 BXGT009017 Alpha-1D adrenergic receptor reviewed G-protein coupled receptor ADRA1D Ki - - -
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A IC50 - - -
P18089 BXGT008379 Alpha-2B adrenergic receptor reviewed G-protein coupled receptor ADRA2B IC50 - - -
P18825 BXGT008426 Alpha-2C adrenergic receptor reviewed G-protein coupled receptor ADRA2C IC50 - - -
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA Ki - - -
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 Ki - - -
P41597 BXGT010268 C-C chemokine receptor type 2 reviewed - CCR2 Ki - - -
P51681 BXGT010878 C-C chemokine receptor type 5 reviewed G-protein coupled receptor CCR5 IC50 - - -
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 Ki - - -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 IC50 '=' 3000 nM
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 IC50 - - -
P21917 BXGT008707 D(4) dopamine receptor reviewed G-protein coupled receptor DRD4 IC50 - - -
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 IC50 - - -
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 Ki '=' 864 nM
P20781 BXGT008598 Glycine receptor subunit beta reviewed - Glrb Ki - - -
P07727 BXGT006662 Glycine receptor subunit alpha-1 reviewed - Glra1 Ki - - -
P24524 BXGT008974 Glycine receptor subunit alpha-3 reviewed - Glra3 Ki - - -
P22771 BXGT008806 Glycine receptor subunit alpha-2 reviewed - Glra2 Ki - - -
P25021 BXGT009004 Histamine H2 receptor reviewed G-protein coupled receptor HRH2 Ki - - -
Q9Y271 BXGT022222 Cysteinyl leukotriene receptor 1 reviewed G-protein coupled receptor CYSLTR1 Ki - - -
P33032 BXGT009689 Melanocortin receptor 5 reviewed G-protein coupled receptor MC5R Ki - - -
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 Ki - - -
P15207 BXGT008096 Androgen receptor reviewed - Ar Anogenital distance '=' 1 mM
Q96RI1 BXGT019727 Bile acid receptor reviewed Nuclear receptor NR1H4 Potency - 6309 nM
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE IC50 - - -
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 8414 nM
P25024 BXGT009005 C-X-C chemokine receptor type 1 reviewed G-protein coupled receptor CXCR1 IC50 - - -
P29466 BXGT009349 Caspase-1 reviewed Enzyme CASP1 Ki - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 IC50 - - -
P06401 BXGT006436 Progesterone receptor reviewed Nuclear receptor PGR IC50 '=' 650 nM
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase reviewed - PDE5A IC50 - - -
P08311 BXGT006762 Cathepsin G reviewed Enzyme CTSG IC50 - - -
P19327 BXGT008472 5-hydroxytryptamine receptor 1A reviewed - Htr1a Ki - - -
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 reviewed Kinase FLT1 Ki - - -
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 reviewed Transporter ABCC2 Activity '=' 125 %
P15207 BXGT008096 Androgen receptor reviewed - Ar Relative antiandrogenic activity '=' 1 -
P15207 BXGT008096 Androgen receptor reviewed - Ar Competition factor '=' 8 -
P10275 BXGT007552 Androgen receptor reviewed Nuclear receptor AR IC50 '=' 670 nM
P15207 BXGT008096 Androgen receptor reviewed - Ar Organ weight '=' 15 mg
P06186 BXGT006419 Progesterone receptor reviewed - PGR McPhail index '=' 1 -
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 2433 nM
P08235 BXGT006751 Mineralocorticoid receptor reviewed Nuclear receptor NR3C2 Ki '=' 2 nM
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 EC50 '=' 3300 nM
P22199 BXGT008741 Mineralocorticoid receptor reviewed - Nr3c2 Relative binding affinity '=' 0 -
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 Ki '=' 32 nM
P08235 BXGT006751 Mineralocorticoid receptor reviewed Nuclear receptor NR3C2 IC50 '=' 60 nM
P50052 BXGT010768 Type-2 angiotensin II receptor reviewed G-protein coupled receptor AGTR2 IC50 - - -
P15207 BXGT008096 Androgen receptor reviewed - Ar Organ weight '=' 16 mg
P15207 BXGT008096 Androgen receptor reviewed - Ar Organ weight '=' 28 mg
P15207 BXGT008096 Androgen receptor reviewed - Ar Tp control '=' 64 %
O15245 BXGT004141 Solute carrier family 22 member 1 reviewed Transporter SLC22A1 Inhibition '=' 87 %
P25025 BXGT009006 C-X-C chemokine receptor type 2 reviewed G-protein coupled receptor CXCR2 IC50 - - -
P35462 BXGT009835 D(3) dopamine receptor reviewed G-protein coupled receptor DRD3 IC50 - - -
A6XA80 BXGT001522 Leukotriene C4 synthase reviewed - LTC4S Ki - - -
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 Ki - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki - - -
P22199 BXGT008741 Mineralocorticoid receptor reviewed - Nr3c2 Activity '=' 0 -
P19793 BXGT008515 Retinoic acid receptor RXR-alpha reviewed Nuclear receptor RXRA Potency - 8912 nM
P11473 BXGT007709 Vitamin D3 receptor reviewed Nuclear receptor VDR Potency - 22387 nM
P15207 BXGT008096 Androgen receptor reviewed - Ar RBA '=' 6 %
P15207 BXGT008096 Androgen receptor reviewed - Ar Tp control '=' 134 %
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b Ki - - -
P25100 BXGT009017 Alpha-1D adrenergic receptor reviewed G-protein coupled receptor ADRA1D IC50 - - -
P08588 BXGT006795 Beta-1 adrenergic receptor reviewed G-protein coupled receptor ADRB1 Ki - - -
P08235 BXGT006751 Mineralocorticoid receptor reviewed Nuclear receptor NR3C2 Activity '=' 4 %
P15207 BXGT008096 Androgen receptor reviewed - Ar Tp control '=' 135 %
P15207 BXGT008096 Androgen receptor reviewed - Ar Tp control '=' 58 %
P15207 BXGT008096 Androgen receptor reviewed - Ar Tp control '=' 14 %
P15207 BXGT008096 Androgen receptor reviewed - Ar Organ weight '=' 10 mg
P15207 BXGT008096 Androgen receptor reviewed - Ar Organ weight '=' 19 mg
P13945 BXGT007972 Beta-3 adrenergic receptor reviewed G-protein coupled receptor ADRB3 IC50 - - -
P32238 BXGT009611 Cholecystokinin receptor type A reviewed G-protein coupled receptor CCKAR Ki - - -
P05181 BXGT006337 Cytochrome P450 2E1 reviewed - CYP2E1 Ki - - -
A6XA80 BXGT001522 Leukotriene C4 synthase reviewed - LTC4S IC50 - - -
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 Ki - - -
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 IC50 - - -
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 Ki - - -
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 2511 nM
P22199 BXGT008741 Mineralocorticoid receptor reviewed - Nr3c2 Activity '=' 1 -
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Ki - - -
P08235 BXGT006751 Mineralocorticoid receptor reviewed Nuclear receptor NR3C2 RBA '=' 4 %
P06186 BXGT006419 Progesterone receptor reviewed - PGR Ratio '=' 21 -
P15207 BXGT008096 Androgen receptor reviewed - Ar Tp control '=' 55 %
P15207 BXGT008096 Androgen receptor reviewed - Ar Tp control '=' 21 %
P15207 BXGT008096 Androgen receptor reviewed - Ar Tp control '=' 20 %
P06186 BXGT006419 Progesterone receptor reviewed - PGR McPhail index '=' 1 -
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 reviewed Kinase ERBB2 Ki - - -
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 IC50 - - -
P08235 BXGT006751 Mineralocorticoid receptor reviewed Nuclear receptor NR3C2 IC50 '=' 11 nM
P07550 BXGT006636 Beta-2 adrenergic receptor reviewed G-protein coupled receptor ADRB2 Ki - - -
P28335 BXGT009255 5-hydroxytryptamine receptor 2C reviewed G-protein coupled receptor HTR2C IC50 - - -
P32241 BXGT009613 Vasoactive intestinal polypeptide receptor 1 reviewed G-protein coupled receptor VIPR1 IC50 - - -
P10275 BXGT007552 Androgen receptor reviewed Nuclear receptor AR Potency - 39810 nM
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 Ki - - -
P29274 BXGT009327 Adenosine receptor A2a reviewed G-protein coupled receptor ADORA2A IC50 - - -
P15207 BXGT008096 Androgen receptor reviewed - Ar Tp control '=' 130 %
P0DMS8 BXGT007506 Adenosine receptor A3 reviewed G-protein coupled receptor ADORA3 IC50 - - -
P13945 BXGT007972 Beta-3 adrenergic receptor reviewed G-protein coupled receptor ADRB3 Ki - - -
P22199 BXGT008741 Mineralocorticoid receptor reviewed - Nr3c2 MRP '=' 100 -
P22199 BXGT008741 Mineralocorticoid receptor reviewed - Nr3c2 RBA '=' 15 %
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 Ki - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 IC50 - - -
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 Ki - - -
P25101 BXGT009018 Endothelin-1 receptor reviewed G-protein coupled receptor EDNRA IC50 - - -
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 IC50 '=' 1902 nM
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase reviewed - HMGCR Ki - - -
P41968 BXGT010275 Melanocortin receptor 3 reviewed G-protein coupled receptor MC3R Ki - - -
P33032 BXGT009689 Melanocortin receptor 5 reviewed G-protein coupled receptor MC5R IC50 - - -
P29476 BXGT009354 Nitric oxide synthase, brain reviewed - Nos1 Ki - - -
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 IC50 - - -
P15207 BXGT008096 Androgen receptor reviewed - Ar IC50 '=' 676 nM
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Ki '>' 1100 nM
P06186 BXGT006419 Progesterone receptor reviewed - PGR McPhail index '=' 1 -
P08235 BXGT006751 Mineralocorticoid receptor reviewed Nuclear receptor NR3C2 IC50 '=' 49 nM
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 Ki - - -
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C reviewed Enzyme PTPRC IC50 - - -
P10275 BXGT007552 Androgen receptor reviewed Nuclear receptor AR Activity - - -
P22199 BXGT008741 Mineralocorticoid receptor reviewed - Nr3c2 RBA '=' 2 %
P06401 BXGT006436 Progesterone receptor reviewed Nuclear receptor PGR Ki '=' 399 nM
P06186 BXGT006419 Progesterone receptor reviewed - PGR McPhail index '=' 1 -
P06186 BXGT006419 Progesterone receptor reviewed - PGR McPhail index '=' 1 -
P15207 BXGT008096 Androgen receptor reviewed - Ar Tp control '=' 56 %
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 Activity - - -
P42330 BXGT010301 Aldo-keto reductase family 1 member C3 reviewed Enzyme AKR1C3 Inhibition '=' 57 %
P0DMS8 BXGT007506 Adenosine receptor A3 reviewed G-protein coupled receptor ADORA3 Ki - - -
P06401 BXGT006436 Progesterone receptor reviewed Nuclear receptor PGR Activity - - -
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 IC50 '=' 4100 nM
P03956 BXGT006120 Interstitial collagenase reviewed Enzyme MMP1 IC50 - - -
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR IC50 - - -
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 reviewed Kinase ERBB2 IC50 - - -
O70528 BXGT005068 5-hydroxytryptamine receptor 4 reviewed - HTR4 Ki - - -
P08235 BXGT006751 Mineralocorticoid receptor reviewed Nuclear receptor NR3C2 Activity - - -
P06186 BXGT006419 Progesterone receptor reviewed - PGR McPhail index '=' 1 -
P15207 BXGT008096 Androgen receptor reviewed - Ar Tp control '=' 65 %
P42330 BXGT010301 Aldo-keto reductase family 1 member C3 reviewed Enzyme AKR1C3 Inhibition '=' 27 %
Q03431 BXGT012714 Parathyroid hormone/parathyroid hormone-related peptide receptor reviewed G-protein coupled receptor PTH1R Potency - 8912 nM
P15207 BXGT008096 Androgen receptor reviewed - Ar Organ weight '=' 32 mg
P08235 BXGT006751 Mineralocorticoid receptor reviewed Nuclear receptor NR3C2 IC50 '=' 1 nM
P24557 BXGT008976 Thromboxane-A synthase reviewed - TBXAS1 Ki - - -
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 5804 nM
P56937 BXGT011205 3-keto-steroid reductase reviewed - HSD17B7 Inhibition '=' 7 %
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 IC50 '=' 5702 nM
P15207 BXGT008096 Androgen receptor reviewed - Ar Organ weight '=' 6 mg
P46720 BXGT010535 Solute carrier organic anion transporter family member 1A1 reviewed - Slco1a1 Activity - - -
P50052 BXGT010768 Type-2 angiotensin II receptor reviewed G-protein coupled receptor AGTR2 Ki - - -
Q9Y271 BXGT022222 Cysteinyl leukotriene receptor 1 reviewed G-protein coupled receptor CYSLTR1 IC50 - - -
P41597 BXGT010268 C-C chemokine receptor type 2 reviewed - CCR2 IC50 - - -
P14416 BXGT008011 D(2) dopamine receptor reviewed G-protein coupled receptor DRD2 Ki - - -
P21397 BXGT008644 Amine oxidase [flavin-containing] A reviewed - MAOA Ki - - -
P49146 BXGT010681 Neuropeptide Y receptor type 2 reviewed G-protein coupled receptor NPY2R Ki - - -
P29476 BXGT009354 Nitric oxide synthase, brain reviewed - Nos1 IC50 - - -
P51679 BXGT010877 C-C chemokine receptor type 4 reviewed G-protein coupled receptor CCR4 IC50 - - -
P51681 BXGT010878 C-C chemokine receptor type 5 reviewed G-protein coupled receptor CCR5 Ki - - -
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 Ki - - -
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 IC50 - - -
P30542 BXGT009436 Adenosine receptor A1 reviewed G-protein coupled receptor ADORA1 Ki - - -
Q96RI1 BXGT019727 Bile acid receptor reviewed Nuclear receptor NR1H4 Potency - 10000 nM
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 IC50 '>' 20000 nM
P25105 BXGT009021 Platelet-activating factor receptor reviewed G-protein coupled receptor PTAFR Ki - - -
P14780 BXGT008053 Matrix metalloproteinase-9 reviewed Enzyme MMP9 IC50 - - -
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 Ki - - -
P41595 BXGT010267 5-hydroxytryptamine receptor 2B reviewed G-protein coupled receptor HTR2B IC50 - - -
P41595 BXGT010267 5-hydroxytryptamine receptor 2B reviewed G-protein coupled receptor HTR2B Ki - - -
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 - - -
P25103 BXGT009020 Substance-P receptor reviewed G-protein coupled receptor TACR1 Ki - - -
P21452 BXGT008653 Substance-K receptor reviewed G-protein coupled receptor TACR2 IC50 - - -
P25105 BXGT009021 Platelet-activating factor receptor reviewed G-protein coupled receptor PTAFR IC50 - - -
O35913 BXGT004540 Solute carrier organic anion transporter family member 1A4 reviewed - Slco1a4 Activity - - -
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 IC50 - - -
O70528 BXGT005068 5-hydroxytryptamine receptor 4 reviewed - HTR4 IC50 - - -
Q63120 BXGT016061 Canalicular multispecific organic anion transporter 1 reviewed - Abcc2 Activity - - -
P06401 BXGT006436 Progesterone receptor reviewed Nuclear receptor PGR IC50 '=' 4000 nM
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 Inhibition '=' -34 %
Q9R1A7 BXGT021413 Nuclear receptor subfamily 1 group I member 2 reviewed - Nr1i2 Potency - 12589 nM
P30542 BXGT009436 Adenosine receptor A1 reviewed G-protein coupled receptor ADORA1 IC50 - - -
P28223 BXGT009239 5-hydroxytryptamine receptor 2A reviewed G-protein coupled receptor HTR2A Ki - - -
P25103 BXGT009020 Substance-P receptor reviewed G-protein coupled receptor TACR1 IC50 - - -
Q96FL8 BXGT019660 Multidrug and toxin extrusion protein 1 reviewed Transporter SLC47A1 IC50 '=' 18600 nM
Q03181 BXGT012701 Peroxisome proliferator-activated receptor delta reviewed Nuclear receptor PPARD Potency - 35481 nM
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b IC50 - - -
P19793 BXGT008515 Retinoic acid receptor RXR-alpha reviewed Nuclear receptor RXRA Potency - 6309 nM
Q03181 BXGT012701 Peroxisome proliferator-activated receptor delta reviewed Nuclear receptor PPARD Potency - 31622 nM
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase reviewed - PDE5A Ki - - -
P12822 BXGT007850 Angiotensin-converting enzyme reviewed - ACE IC50 - - -
P22199 BXGT008741 Mineralocorticoid receptor reviewed - Nr3c2 Binding '=' 32 %
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 EC50 '>' 20000 nM
Q08209 BXGT012968 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform reviewed - PPP3CA Ki - - -
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK IC50 - - -
P28223 BXGT009239 5-hydroxytryptamine receptor 2A reviewed G-protein coupled receptor HTR2A IC50 - - -
P15207 BXGT008096 Androgen receptor reviewed - Ar Ki '=' 90 nM
P10275 BXGT007552 Androgen receptor reviewed Nuclear receptor AR IC50 '=' 523 nM
P06401 BXGT006436 Progesterone receptor reviewed Nuclear receptor PGR IC50 '>' 10000 nM
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 IC50 '>' 20000 nM
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA IC50 - - -
P21452 BXGT008653 Substance-K receptor reviewed G-protein coupled receptor TACR2 Ki - - -
P24557 BXGT008976 Thromboxane-A synthase reviewed - TBXAS1 IC50 - - -
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 Ki - - -
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 IC50 '=' 1400 nM
Q690N0 BXGT016199 Progesterone receptor unreviewed - PGR Ki '=' 217 nM
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 IC50 - - -
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 IC50 - - -
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 Ki - - -
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 IC50 - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Ki - - -
P25025 BXGT009006 C-X-C chemokine receptor type 2 reviewed G-protein coupled receptor CXCR2 Ki - - -
P21917 BXGT008707 D(4) dopamine receptor reviewed G-protein coupled receptor DRD4 Ki - - -
P35367 BXGT009821 Histamine H1 receptor reviewed G-protein coupled receptor HRH1 Ki - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki - - -
P30411 BXGT009424 B2 bradykinin receptor reviewed G-protein coupled receptor BDKRB2 Ki - - -
P32238 BXGT009611 Cholecystokinin receptor type A reviewed G-protein coupled receptor CCKAR IC50 - - -
P35367 BXGT009821 Histamine H1 receptor reviewed G-protein coupled receptor HRH1 IC50 - - -
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 reviewed Transporter SLCO1B1 Inhibition '=' 52 %
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a IC50 - - -
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a Ki - - -
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A Ki - - -
P07550 BXGT006636 Beta-2 adrenergic receptor reviewed G-protein coupled receptor ADRB2 IC50 - - -
P07943 BXGT006700 Aldo-keto reductase family 1 member B1 reviewed - Akr1b1 IC50 - - -
P10828 BXGT007624 Thyroid hormone receptor beta reviewed Nuclear receptor THRB Potency - 28183 nM
P70502 BXGT011672 Solute carrier organic anion transporter family member 1A3 reviewed - Slco1a3 Activity - - -
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 IC50 '=' 23600 nM
P18825 BXGT008426 Alpha-2C adrenergic receptor reviewed G-protein coupled receptor ADRA2C Ki - - -
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 IC50 - - -
O94956 BXGT005343 Solute carrier organic anion transporter family member 2B1 reviewed Transporter SLCO2B1 Inhibition '=' -82 %
P06401 BXGT006436 Progesterone receptor reviewed Nuclear receptor PGR IC50 '=' 1400 nM
P15207 BXGT008096 Androgen receptor reviewed - Ar Tp control '=' 57 %
P15207 BXGT008096 Androgen receptor reviewed - Ar Tp control '=' 51 %
P15207 BXGT008096 Androgen receptor reviewed - Ar Tp control '=' 43 %
P15207 BXGT008096 Androgen receptor reviewed - Ar Tp control '=' 38 %
P06186 BXGT006419 Progesterone receptor reviewed - PGR McPhail index '=' 1 -
P22199 BXGT008741 Mineralocorticoid receptor reviewed - Nr3c2 RBA '=' 11 %
P22199 BXGT008741 Mineralocorticoid receptor reviewed - Nr3c2 Activity '=' 2 -
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 Activity - - -
P10275 BXGT007552 Androgen receptor reviewed Nuclear receptor AR EC50 '>' 20000 nM
Q77YF9 BXGT016886 Protein Vpr unreviewed - vpr Potency - 3162 nM
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Activity - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Activity - - -
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 reviewed Transporter SLCO1B1 Inhibition '=' 88 %
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 7307 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00400 French plantain Musa X paradisiaca Fruits
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease