Showing entry for Vincristine


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0034768
Compound NameVincristine
Structure
FormulaC46H56N4O10
InchiKeyOGWKCGZFUXNPDA-XQKSVPLYSA-N
SMILESO=CN1c2cc(OC)c(cc2[C@]23[C@@H]1[C@@](O)(C(=O)OC)[C@H](OC(=O)C)[C@]1([C@@H]3N(CC2)CC=C1)CC)[C@]1(C[C@@H]2CN(CCc3c1[nH]c1c3cccc1)C[C@](C2)(O)CC)C(=O)OC
InchiInChI=1S/C46H56N4O10/c1-7-42(55)22-28-23-45(40(53)58-5,36-30(14-18-48(24-28)25-42)29-12-9-10-13-33(29)47-36)32-20-31-34(21-35(32)57-4)50(26-51)38-44(31)16-19-49-17-11-15-43(8-2,37(44)49)39(60-27(3)52)46(38,56)41(54)59-6/h9-13,15,20-21,26,28,37-39,47,55-56
IUPAC
Molecular Weight824.4
Pubchem Id5978
Chembl IdCHEMBL90555
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 50139772
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT005891 Tubulin alpha-1A chain reviewed TUBA1A - 220 - -
reviewed BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 17600 - - -
reviewed BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 - 36780 - -
reviewed BXGT009728 Multidrug resistance-associated protein 1 reviewed Transporter ABCC1 - 70000 - -
reviewed BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 213000 - - -
reviewed BXGT019389 Canalicular multispecific organic anion transporter 1 reviewed Transporter ABCC2 802000 - - -
reviewed BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 9800 - - -
reviewed BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 - 11000 - -
reviewed BXGT022334 Solute carrier organic anion transporter family member 1B1 reviewed Transporter SLCO1B1 42000 - - -
reviewed BXGT022334 Solute carrier organic anion transporter family member 1B1 reviewed Transporter SLCO1B1 - 44000 - -
CHEMBL CHEMBL90555
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA IC50 - - -
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A IC50 '=' 220 nM
Q64133 BXGT016109 Amine oxidase [flavin-containing] A reviewed - Maoa Activity - - -
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Activity - - -
P51679 BXGT010877 C-C chemokine receptor type 4 reviewed G-protein coupled receptor CCR4 IC50 - - -
P18825 BXGT008426 Alpha-2C adrenergic receptor reviewed G-protein coupled receptor ADRA2C Ki - - -
P21554 BXGT008662 Cannabinoid receptor 1 reviewed G-protein coupled receptor CNR1 Ki - - -
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 Ki - - -
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 Ki - - -
P05181 BXGT006337 Cytochrome P450 2E1 reviewed - CYP2E1 Ki - - -
P41968 BXGT010275 Melanocortin receptor 3 reviewed G-protein coupled receptor MC3R IC50 - - -
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase reviewed - PDE5A IC50 - - -
Q690N0 BXGT016199 Progesterone receptor unreviewed - PGR IC50 - - -
P03956 BXGT006120 Interstitial collagenase reviewed Enzyme MMP1 Ki - - -
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR IC50 - - -
P28564 BXGT009272 5-hydroxytryptamine receptor 1B reviewed - Htr1b Ki - - -
Q63120 BXGT016061 Canalicular multispecific organic anion transporter 1 reviewed - Abcc2 Activity '=' 42 %
P02545 BXGT005889 Prelamin-A/C reviewed - LMNA Potency '=' 1 nM
P30988 BXGT009491 Calcitonin receptor reviewed G-protein coupled receptor CALCR IC50 - - -
P18825 BXGT008426 Alpha-2C adrenergic receptor reviewed G-protein coupled receptor ADRA2C IC50 - - -
P41597 BXGT010268 C-C chemokine receptor type 2 reviewed - CCR2 Ki - - -
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 IC50 - - -
P35462 BXGT009835 D(3) dopamine receptor reviewed G-protein coupled receptor DRD3 IC50 - - -
P25929 BXGT009078 Neuropeptide Y receptor type 1 reviewed G-protein coupled receptor NPY1R Ki - - -
P29466 BXGT009349 Caspase-1 reviewed Enzyme CASP1 IC50 - - -
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK IC50 - - -
P15207 BXGT008096 Androgen receptor reviewed - Ar Ki - - -
P37288 BXGT009977 Vasopressin V1a receptor reviewed G-protein coupled receptor AVPR1A IC50 - - -
P25100 BXGT009017 Alpha-1D adrenergic receptor reviewed G-protein coupled receptor ADRA1D IC50 - - -
P07550 BXGT006636 Beta-2 adrenergic receptor reviewed G-protein coupled receptor ADRB2 IC50 - - -
P05181 BXGT006337 Cytochrome P450 2E1 reviewed - CYP2E1 IC50 - - -
P21917 BXGT008707 D(4) dopamine receptor reviewed G-protein coupled receptor DRD4 Ki - - -
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Ki - - -
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 IC50 - - -
P29466 BXGT009349 Caspase-1 reviewed Enzyme CASP1 Ki - - -
P25094 BXGT009014 Peripheral myelin protein 22 reviewed - Pmp22 Potency - 90 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 125 nM
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A Activity - - -
P02554 BXGT005892 Tubulin beta chain reviewed - Activity - - -
P33527 BXGT009728 Multidrug resistance-associated protein 1 reviewed Transporter ABCC1 Activity - - -
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Activity - - -
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Activity - - -
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Activity - - -
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Activity - - -
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Activity - - -
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Activity - - -
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Activity - - -
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Activity - - -
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Activity - - -
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Activity - - -
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Activity - - -
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Activity - - -
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Activity - - -
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Activity - - -
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Activity - - -
P15127 BXGT008085 Insulin receptor reviewed - Insr IC50 - - -
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - Inhibition - - -
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - Inhibition - - -
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B Inhibition - - -
P25103 BXGT009020 Substance-P receptor reviewed G-protein coupled receptor TACR1 Ki - - -
P12530 BXGT007827 Arachidonate 15-lipoxygenase reviewed - ALOX15 Ki - - -
P06241 BXGT006429 Tyrosine-protein kinase Fyn reviewed Kinase FYN Ki - - -
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK Ki - - -
P50406 BXGT010796 5-hydroxytryptamine receptor 6 reviewed G-protein coupled receptor HTR6 IC50 - - -
P07943 BXGT006700 Aldo-keto reductase family 1 member B1 reviewed - Akr1b1 Ki - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Activity - - -
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Inhibition - - -
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Inhibition - - -
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Inhibition - - -
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Inhibition - - -
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Inhibition - - -
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Inhibition - - -
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Inhibition - - -
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Inhibition - - -
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Inhibition - - -
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Inhibition - - -
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Inhibition - - -
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Inhibition - - -
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Inhibition - - -
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Inhibition - - -
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Inhibition - - -
P20781 BXGT008598 Glycine receptor subunit beta reviewed - Glrb IC50 - - -
P07727 BXGT006662 Glycine receptor subunit alpha-1 reviewed - Glra1 IC50 - - -
P24524 BXGT008974 Glycine receptor subunit alpha-3 reviewed - Glra3 IC50 - - -
P22771 BXGT008806 Glycine receptor subunit alpha-2 reviewed - Glra2 IC50 - - -
P12530 BXGT007827 Arachidonate 15-lipoxygenase reviewed - ALOX15 IC50 - - -
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 IC50 - - -
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 1800 nM
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 1800 nM
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 1800 nM
P30542 BXGT009436 Adenosine receptor A1 reviewed G-protein coupled receptor ADORA1 IC50 - - -
P30542 BXGT009436 Adenosine receptor A1 reviewed G-protein coupled receptor ADORA1 Ki - - -
P18089 BXGT008379 Alpha-2B adrenergic receptor reviewed G-protein coupled receptor ADRA2B Ki - - -
P08588 BXGT006795 Beta-1 adrenergic receptor reviewed G-protein coupled receptor ADRB1 Ki - - -
P51679 BXGT010877 C-C chemokine receptor type 4 reviewed G-protein coupled receptor CCR4 Ki - - -
P51681 BXGT010878 C-C chemokine receptor type 5 reviewed G-protein coupled receptor CCR5 Ki - - -
P25024 BXGT009005 C-X-C chemokine receptor type 1 reviewed G-protein coupled receptor CXCR1 IC50 - - -
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 IC50 - - -
P08588 BXGT006795 Beta-1 adrenergic receptor reviewed G-protein coupled receptor ADRB1 IC50 - - -
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 IC50 - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki - - -
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Papp '=' 14 nm/s
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a Ki - - -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 - - -
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 - - -
P21452 BXGT008653 Substance-K receptor reviewed G-protein coupled receptor TACR2 IC50 - - -
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 reviewed Kinase FLT1 Ki - - -
P25105 BXGT009021 Platelet-activating factor receptor reviewed G-protein coupled receptor PTAFR IC50 - - -
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 Ki - - -
Q690N0 BXGT016199 Progesterone receptor unreviewed - PGR Ki - - -
P03956 BXGT006120 Interstitial collagenase reviewed Enzyme MMP1 IC50 - - -
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B GTPase Activity '=' 5 -
P25929 BXGT009078 Neuropeptide Y receptor type 1 reviewed G-protein coupled receptor NPY1R IC50 - - -
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA Ki - - -
Q9QY30 BXGT021389 Bile salt export pump reviewed - Abcb11 Activity - - -
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE Ki - - -
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b Ki - - -
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 Ki - - -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 Ki - - -
Q9Y271 BXGT022222 Cysteinyl leukotriene receptor 1 reviewed G-protein coupled receptor CYSLTR1 IC50 - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 - - -
O70528 BXGT005068 5-hydroxytryptamine receptor 4 reviewed - HTR4 IC50 - - -
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE IC50 - - -
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Inhibition '=' 87 %
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Inhibition '=' 87 %
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Inhibition '=' 87 %
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Inhibition '=' 87 %
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Inhibition '=' 87 %
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Inhibition '=' 87 %
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Inhibition '=' 87 %
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Inhibition '=' 87 %
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Inhibition '=' 87 %
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Inhibition '=' 87 %
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Inhibition '=' 87 %
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Inhibition '=' 87 %
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Inhibition '=' 87 %
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Inhibition '=' 87 %
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Inhibition '=' 87 %
P50052 BXGT010768 Type-2 angiotensin II receptor reviewed G-protein coupled receptor AGTR2 IC50 - - -
P32238 BXGT009611 Cholecystokinin receptor type A reviewed G-protein coupled receptor CCKAR Ki - - -
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 IC50 - - -
P08311 BXGT006762 Cathepsin G reviewed Enzyme CTSG Ki - - -
Q08209 BXGT012968 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform reviewed - PPP3CA IC50 - - -
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A Ki - - -
P50052 BXGT010768 Type-2 angiotensin II receptor reviewed G-protein coupled receptor AGTR2 Ki - - -
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B GTPase Activity '=' 0 -
Q25270 BXGT013897 Beta-tubulin unreviewed - beta-tubulin Inhibition '=' 83 %
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 reviewed Transporter SLCO1B1 Ki '=' 42000 nM
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 reviewed Transporter SLCO1B1 IC50 '=' 44000 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Papp '=' 2 nm/s
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Ki1 '=' 0 uM
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A Inhibition - - -
P02554 BXGT005892 Tubulin beta chain reviewed - Inhibition - - -
P28223 BXGT009239 5-hydroxytryptamine receptor 2A reviewed G-protein coupled receptor HTR2A Ki - - -
P41595 BXGT010267 5-hydroxytryptamine receptor 2B reviewed G-protein coupled receptor HTR2B IC50 - - -
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 237 nM
P37288 BXGT009977 Vasopressin V1a receptor reviewed G-protein coupled receptor AVPR1A Ki - - -
P21397 BXGT008644 Amine oxidase [flavin-containing] A reviewed - MAOA Ki - - -
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 Ki - - -
P49146 BXGT010681 Neuropeptide Y receptor type 2 reviewed G-protein coupled receptor NPY2R Ki - - -
P28335 BXGT009255 5-hydroxytryptamine receptor 2C reviewed G-protein coupled receptor HTR2C Ki - - -
P29274 BXGT009327 Adenosine receptor A2a reviewed G-protein coupled receptor ADORA2A Ki - - -
P0DMS8 BXGT007506 Adenosine receptor A3 reviewed G-protein coupled receptor ADORA3 Ki - - -
P25100 BXGT009017 Alpha-1D adrenergic receptor reviewed G-protein coupled receptor ADRA1D Ki - - -
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A IC50 - - -
P18089 BXGT008379 Alpha-2B adrenergic receptor reviewed G-protein coupled receptor ADRA2B IC50 - - -
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 IC50 - - -
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 Ki - - -
P30411 BXGT009424 B2 bradykinin receptor reviewed G-protein coupled receptor BDKRB2 Ki - - -
P41597 BXGT010268 C-C chemokine receptor type 2 reviewed - CCR2 IC50 - - -
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 Ki - - -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 IC50 - - -
P14416 BXGT008011 D(2) dopamine receptor reviewed G-protein coupled receptor DRD2 IC50 - - -
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 Ki - - -
P35367 BXGT009821 Histamine H1 receptor reviewed G-protein coupled receptor HRH1 IC50 - - -
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase reviewed - HMGCR IC50 - - -
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase reviewed - HMGCR Ki - - -
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 Ki - - -
Q08209 BXGT012968 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform reviewed - PPP3CA Ki - - -
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Ki '=' 213000 nM
A6XA80 BXGT001522 Leukotriene C4 synthase reviewed - LTC4S IC50 - - -
A6XA80 BXGT001522 Leukotriene C4 synthase reviewed - LTC4S Ki - - -
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 IC50 - - -
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 Ki - - -
P06241 BXGT006429 Tyrosine-protein kinase Fyn reviewed Kinase FYN IC50 - - -
P28564 BXGT009272 5-hydroxytryptamine receptor 1B reviewed - Htr1b IC50 - - -
P41595 BXGT010267 5-hydroxytryptamine receptor 2B reviewed G-protein coupled receptor HTR2B Ki - - -
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Ki - - -
P19327 BXGT008472 5-hydroxytryptamine receptor 1A reviewed - Htr1a Ki - - -
P19327 BXGT008472 5-hydroxytryptamine receptor 1A reviewed - Htr1a IC50 - - -
P28223 BXGT009239 5-hydroxytryptamine receptor 2A reviewed G-protein coupled receptor HTR2A IC50 - - -
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 Inhibition '=' 65 %
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 Ki - - -
P29476 BXGT009354 Nitric oxide synthase, brain reviewed - Nos1 Ki - - -
Q9WKE8 BXGT021921 Reverse transcriptase unreviewed - reverse IC50 '>' 200 ug.mL-1
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a IC50 - - -
P33032 BXGT009689 Melanocortin receptor 5 reviewed G-protein coupled receptor MC5R IC50 - - -
P50406 BXGT010796 5-hydroxytryptamine receptor 6 reviewed G-protein coupled receptor HTR6 Ki - - -
P29274 BXGT009327 Adenosine receptor A2a reviewed G-protein coupled receptor ADORA2A IC50 - - -
P25101 BXGT009018 Endothelin-1 receptor reviewed G-protein coupled receptor EDNRA Ki - - -
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 Ki - - -
P32245 BXGT009614 Melanocortin receptor 4 reviewed G-protein coupled receptor MC4R Ki - - -
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 IC50 '=' 11000 nM
O94956 BXGT005343 Solute carrier organic anion transporter family member 2B1 reviewed Transporter SLCO2B1 Inhibition '=' 13 %
Q25270 BXGT013897 Beta-tubulin unreviewed - beta-tubulin IC50 '<' 1000 nM
P32241 BXGT009613 Vasoactive intestinal polypeptide receptor 1 reviewed G-protein coupled receptor VIPR1 Ki - - -
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 IC50 '=' 500 nM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 500 nM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A IC50 '=' 500 nM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E IC50 '=' 500 nM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C IC50 '=' 500 nM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B IC50 '=' 500 nM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB IC50 '=' 500 nM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 IC50 '=' 500 nM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A IC50 '=' 500 nM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A IC50 '=' 500 nM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 IC50 '=' 500 nM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A IC50 '=' 500 nM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C IC50 '=' 500 nM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 IC50 '=' 500 nM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B IC50 '=' 500 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 % maximum response '=' 8 %
P29476 BXGT009354 Nitric oxide synthase, brain reviewed - Nos1 IC50 - - -
P25101 BXGT009018 Endothelin-1 receptor reviewed G-protein coupled receptor EDNRA IC50 - - -
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 reviewed Transporter SLCO1B1 Inhibition '=' 28 %
P25094 BXGT009014 Peripheral myelin protein 22 reviewed - Pmp22 Potency - 281 nM
O35379 BXGT004525 Multidrug resistance-associated protein 1 reviewed - Abcc1 Activity - - -
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 reviewed Transporter ABCC2 Activity - - -
P11926 BXGT007760 Ornithine decarboxylase reviewed Enzyme ODC1 Activity - - -
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Ki2 '=' 148 uM
Q7TMS5 BXGT017145 ATP-binding cassette sub-family G member 2 reviewed - Abcg2 Activity - - -
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 Ki '=' 9800 nM
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 reviewed Transporter SLCO1B1 Inhibition '=' 3 %
P42858 BXGT010341 Huntingtin reviewed - HTT Potency '=' 17 nM
P21452 BXGT008653 Substance-K receptor reviewed G-protein coupled receptor TACR2 Ki - - -
P24557 BXGT008976 Thromboxane-A synthase reviewed - TBXAS1 Ki - - -
P35367 BXGT009821 Histamine H1 receptor reviewed G-protein coupled receptor HRH1 Ki - - -
P49146 BXGT010681 Neuropeptide Y receptor type 2 reviewed G-protein coupled receptor NPY2R IC50 - - -
P12822 BXGT007850 Angiotensin-converting enzyme reviewed - ACE Ki - - -
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE Ki - - -
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 IC50 - - -
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 Ki - - -
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 Ki - - -
Q96QA9 BXGT019717 Multidrug resistance associated protein unreviewed - MRP3 Activity '=' 39 %
P15127 BXGT008085 Insulin receptor reviewed - Insr Ki - - -
P21917 BXGT008707 D(4) dopamine receptor reviewed G-protein coupled receptor DRD4 IC50 - - -
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Activity '=' 747 a.u.
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Activity '=' 747 a.u.
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Activity '=' 747 a.u.
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Activity '=' 747 a.u.
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Activity '=' 747 a.u.
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Activity '=' 747 a.u.
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Activity '=' 747 a.u.
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Activity '=' 747 a.u.
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Activity '=' 747 a.u.
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Activity '=' 747 a.u.
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Activity '=' 747 a.u.
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Activity '=' 747 a.u.
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Activity '=' 747 a.u.
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Activity '=' 747 a.u.
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Activity '=' 747 a.u.
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 reviewed Transporter ABCC2 Ki '=' 802000 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Ratio_Papp '=' 6 -
P14780 BXGT008053 Matrix metalloproteinase-9 reviewed Enzyme MMP9 Ki - - -
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 79432 nM
P25105 BXGT009021 Platelet-activating factor receptor reviewed G-protein coupled receptor PTAFR Ki - - -
P08311 BXGT006762 Cathepsin G reviewed Enzyme CTSG IC50 - - -
P12822 BXGT007850 Angiotensin-converting enzyme reviewed - ACE IC50 - - -
Q9Y271 BXGT022222 Cysteinyl leukotriene receptor 1 reviewed G-protein coupled receptor CYSLTR1 Ki - - -
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 IC50 - - -
P15207 BXGT008096 Androgen receptor reviewed - Ar IC50 - - -
P25021 BXGT009004 Histamine H2 receptor reviewed G-protein coupled receptor HRH2 Ki - - -
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 25 nM
Q8BW75 BXGT017924 Amine oxidase [flavin-containing] B reviewed - Maob Activity - - -
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 Ki '=' 17600 nM
P21447 BXGT008651 ATP-dependent translocase ABCB1 reviewed - Abcb1a Activity - - -
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Ratio_ATPase activity '=' 1 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki - - -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 Ki - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 IC50 - - -
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 Ki - - -
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 IC50 - - -
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Activity '=' 722 a.u.
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Activity '=' 722 a.u.
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Activity '=' 722 a.u.
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Activity '=' 722 a.u.
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Activity '=' 722 a.u.
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Activity '=' 722 a.u.
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Activity '=' 722 a.u.
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Activity '=' 722 a.u.
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Activity '=' 722 a.u.
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Activity '=' 722 a.u.
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Activity '=' 722 a.u.
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Activity '=' 722 a.u.
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Activity '=' 722 a.u.
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Activity '=' 722 a.u.
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Activity '=' 722 a.u.
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 reviewed Kinase ERBB2 IC50 - - -
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C reviewed Enzyme PTPRC Ki - - -
P13945 BXGT007972 Beta-3 adrenergic receptor reviewed G-protein coupled receptor ADRB3 Ki - - -
P30988 BXGT009491 Calcitonin receptor reviewed G-protein coupled receptor CALCR Ki - - -
P21554 BXGT008662 Cannabinoid receptor 1 reviewed G-protein coupled receptor CNR1 IC50 - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Ki - - -
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 reviewed Transcription factor SMAD3 Potency - 562 nM
P25103 BXGT009020 Substance-P receptor reviewed G-protein coupled receptor TACR1 IC50 - - -
P24557 BXGT008976 Thromboxane-A synthase reviewed - TBXAS1 IC50 - - -
P32241 BXGT009613 Vasoactive intestinal polypeptide receptor 1 reviewed G-protein coupled receptor VIPR1 IC50 - - -
P20781 BXGT008598 Glycine receptor subunit beta reviewed - Glrb Ki - - -
P07727 BXGT006662 Glycine receptor subunit alpha-1 reviewed - Glra1 Ki - - -
P24524 BXGT008974 Glycine receptor subunit alpha-3 reviewed - Glra3 Ki - - -
P22771 BXGT008806 Glycine receptor subunit alpha-2 reviewed - Glra2 Ki - - -
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 IC50 - - -
Q5T3U5 BXGT015846 Multidrug resistance-associated protein 7 reviewed Transporter ABCC10 Activity '=' 18 %
O70528 BXGT005068 5-hydroxytryptamine receptor 4 reviewed - HTR4 Ki - - -
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 Ki - - -
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Inhibition '=' 77 %
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Inhibition '=' 77 %
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Inhibition '=' 77 %
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Inhibition '=' 77 %
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Inhibition '=' 77 %
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Inhibition '=' 77 %
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Inhibition '=' 77 %
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Inhibition '=' 77 %
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Inhibition '=' 77 %
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Inhibition '=' 77 %
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Inhibition '=' 77 %
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Inhibition '=' 77 %
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Inhibition '=' 77 %
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Inhibition '=' 77 %
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Inhibition '=' 77 %
P32245 BXGT009614 Melanocortin receptor 4 reviewed G-protein coupled receptor MC4R IC50 - - -
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 Ki - - -
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 IC50 - - -
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 IC50 - - -
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 IC50 - - -
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 reviewed Transporter ABCC2 Activity '=' 82 %
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 Inhibition '=' 59 %
P25025 BXGT009006 C-X-C chemokine receptor type 2 reviewed G-protein coupled receptor CXCR2 Ki - - -
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 IC50 - - -
P33032 BXGT009689 Melanocortin receptor 5 reviewed G-protein coupled receptor MC5R Ki - - -
P21397 BXGT008644 Amine oxidase [flavin-containing] A reviewed - MAOA IC50 - - -
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b IC50 - - -
P07943 BXGT006700 Aldo-keto reductase family 1 member B1 reviewed - Akr1b1 IC50 - - -
P30411 BXGT009424 B2 bradykinin receptor reviewed G-protein coupled receptor BDKRB2 IC50 - - -
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 IC50 - - -
P51681 BXGT010878 C-C chemokine receptor type 5 reviewed G-protein coupled receptor CCR5 IC50 - - -
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 Ki - - -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 IC50 - - -
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 reviewed Kinase FLT1 IC50 - - -
P25025 BXGT009006 C-X-C chemokine receptor type 2 reviewed G-protein coupled receptor CXCR2 IC50 - - -
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 IC50 - - -
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 IC50 - - -
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 Ki - - -
P41968 BXGT010275 Melanocortin receptor 3 reviewed G-protein coupled receptor MC3R Ki - - -
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 IC50 - - -
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 Ki - - -
P14780 BXGT008053 Matrix metalloproteinase-9 reviewed Enzyme MMP9 IC50 - - -
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 reviewed Kinase ERBB2 Ki - - -
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE IC50 - - -
P0DMS8 BXGT007506 Adenosine receptor A3 reviewed G-protein coupled receptor ADORA3 IC50 - - -
P25024 BXGT009005 C-X-C chemokine receptor type 1 reviewed G-protein coupled receptor CXCR1 Ki - - -
P32238 BXGT009611 Cholecystokinin receptor type A reviewed G-protein coupled receptor CCKAR IC50 - - -
P07550 BXGT006636 Beta-2 adrenergic receptor reviewed G-protein coupled receptor ADRB2 Ki - - -
P13945 BXGT007972 Beta-3 adrenergic receptor reviewed G-protein coupled receptor ADRB3 IC50 - - -
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 Ki - - -
P14416 BXGT008011 D(2) dopamine receptor reviewed G-protein coupled receptor DRD2 Ki - - -
P35462 BXGT009835 D(3) dopamine receptor reviewed G-protein coupled receptor DRD3 Ki - - -
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 IC50 - - -
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 IC50 - - -
P25021 BXGT009004 Histamine H2 receptor reviewed G-protein coupled receptor HRH2 IC50 - - -
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 Ki - - -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 IC50 - - -
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 IC50 '=' 36780 nM
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 IC50 - - -
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A Ratio IC50 '=' 2 -
P02554 BXGT005892 Tubulin beta chain reviewed - Ratio IC50 '=' 2 -
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 298 nM
P33527 BXGT009728 Multidrug resistance-associated protein 1 reviewed Transporter ABCC1 IC50 '=' 70000 nM
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 17782 nM
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase reviewed - PDE5A Ki - - -
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C reviewed Enzyme PTPRC IC50 - - -
P28335 BXGT009255 5-hydroxytryptamine receptor 2C reviewed G-protein coupled receptor HTR2C IC50 - - -
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR Ki - - -
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF05552 Catharanthus roseus Catharanthus roseus Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease