Showing entry for Serine/threonine-protein kinase BRSK1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018808
Protein NameSerine/threonine-protein kinase BRSK1
Uniport IdQ8TDC3
GeneBRSK1
Gene Id84446
DomainPkinase
Pfam PF00069  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0008306 associative learning
Biological Process GO:0007409 axonogenesis
Biological Process GO:0006974 cellular response to DNA damage stimulus
Biological Process GO:0051298 centrosome duplication
Biological Process GO:0030010 establishment of cell polarity
Biological Process GO:0000086 G2/M transition of mitotic cell cycle
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0090176 microtubule cytoskeleton organization involved in establishment of planar polarity
Biological Process GO:0007095 mitotic G2 DNA damage checkpoint
Biological Process GO:0030182 neuron differentiation
Biological Process GO:0007269 neurotransmitter secretion
Biological Process GO:0018105 peptidyl-serine phosphorylation
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0050770 regulation of axonogenesis
Biological Process GO:0010975 regulation of neuron projection development
Biological Process GO:0048167 regulation of synaptic plasticity
Biological Process GO:2000807 regulation of synaptic vesicle clustering
Biological Process GO:0009411 response to UV
Biological Process GO:0099504 synaptic vesicle cycle
molecular function GO:0005524 ATP binding
molecular function GO:0043015 gamma-tubulin binding
molecular function GO:0000287 magnesium ion binding
molecular function GO:0019901 protein kinase binding
molecular function GO:0004674 protein serine/threonine kinase activity
molecular function GO:0048156 tau protein binding
molecular function GO:0050321 tau-protein kinase activity
cellular component GO:0030054 cell junction
cellular component GO:0005813 centrosome
cellular component GO:0005737 cytoplasm
cellular component GO:0150034 distal axon
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0048786 presynaptic active zone
cellular component GO:0008021 synaptic vesicle
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0017665 BXGD001141 Membranous glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Immune System Diseases
C0018081 BXGD001171 Gonorrhea Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0025322 BXGD001863 Premature Menopause Female Urogenital Diseases and Pregnancy Complications
C0027651 BXGD002009 Neoplasms Neoplasms
C0085215 BXGD003141 Ovarian Failure, Premature Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0278701 BXGD006566 Gastric Adenocarcinoma Digestive System Diseases; Neoplasms
C0278704 BXGD006567 Malignant Childhood Neoplasm Neoplasms
C0278883 BXGD006614 Metastatic melanoma Neoplasms
C0345958 BXGD007751 Large cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1629609 BXGD013479 Age at menopause
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0012352 Chelerythrine 348.12
BXGC0024554 D-luciferin 280
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein