Showing entry for Relaxin receptor 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019009
Protein NameRelaxin receptor 2
Uniport IdQ8WXD0
GeneRXFP2
Gene Id122042
Domain7tm_1; Ldl_recept_a; LRR_8
Pfam PF00001   PF00057   PF13855  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction
5. Organismal Systems 5.2 Endocrine system hsa04926 Relaxin signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007190 activation of adenylate cyclase activity
Biological Process GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
Biological Process GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0009755 hormone-mediated signaling pathway
Biological Process GO:0008584 male gonad development
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0001556 oocyte maturation
Biological Process GO:0043950 positive regulation of cAMP-mediated signaling
molecular function GO:0008528 G protein-coupled peptide receptor activity
molecular function GO:0017046 peptide hormone binding
molecular function GO:0016500 protein-hormone receptor activity
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-1643685 Disease
R-HSA-372790 Signaling by GPCR
R-HSA-373076 Class A/1 (Rhodopsin-like receptors)
R-HSA-375276 Peptide ligand-binding receptors
R-HSA-388396 GPCR downstream signalling
R-HSA-418555 G alpha (s) signalling events
R-HSA-444821 Relaxin receptors
R-HSA-500792 GPCR ligand binding
R-HSA-5663205 Infectious disease
R-HSA-9658195 Leishmania infection
R-HSA-9660821 ADORA2B mediated anti-inflammatory cytokines production
R-HSA-9662851 Anti-inflammatory response favouring Leishmania parasite infection
R-HSA-9664433 Leishmania parasite growth and survival
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0010417 BXGD000670 Cryptorchidism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Male Urogenital Diseases; Endocrine System Diseases
C0023267 BXGD001626 Fibroid Tumor Neoplasms
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0042133 BXGD002960 Uterine Fibroids Neoplasms
C0151721 BXGD003465 Testicular hypogonadism Endocrine System Diseases
C0153594 BXGD003669 Malignant neoplasm of testis Neoplasms; Male Urogenital Diseases; Endocrine System Diseases
C0238461 BXGD004936 Anaplastic thyroid carcinoma Neoplasms
C0238462 BXGD004937 Medullary carcinoma of thyroid Neoplasms; Endocrine System Diseases
C0342190 BXGD007440 C-cell hyperplasia of thyroid Pathological Conditions, Signs and Symptoms; Endocrine System Diseases
C0431663 BXGD008700 Bilateral Cryptorchidism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Male Urogenital Diseases; Endocrine System Diseases
C0520578 BXGD009097 Retractile testis Male Urogenital Diseases; Endocrine System Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0855197 BXGD011079 Malignant Testicular Germ Cell Tumor Neoplasms; Male Urogenital Diseases; Endocrine System Diseases
C1611743 BXGD013456 Familial (FPAH)
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0017933 Sulfuretin 270.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein