Showing entry for Malignant Testicular Germ Cell Tumor


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD011079
Disease NameMalignant Testicular Germ Cell Tumor
Disease CUI IdC0855197
MeSH Codes C04   C12   C19  
Disease Class NameNeoplasms; Male Urogenital Diseases; Endocrine System Diseases
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O15375 BXGT004158 Monocarboxylate transporter 6 9121 reviewed Transporter
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O75223 BXGT005106 Gamma-glutamylcyclotransferase 79017 reviewed
P01215 BXGT005743 Glycoprotein hormones alpha chain 1081 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04798 BXGT006265 Cytochrome P450 1A1 1543 reviewed Enzyme
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C 5788 reviewed Enzyme
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit 3815 reviewed Kinase
P10909 BXGT007630 Clusterin 1191 reviewed
P13489 BXGT007913 Ribonuclease inhibitor 6050 reviewed Transcription factor
P14174 BXGT007991 Macrophage migration inhibitory factor 4282 reviewed
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P16455 BXGT008229 Methylated-DNA--protein-cysteine methyltransferase 4255 reviewed
P18074 BXGT008374 General transcription and DNA repair factor IIH helicase subunit XPD 2068 reviewed Enzyme
P19544 BXGT008494 Wilms tumor protein 7490 reviewed Nucleic acid binding
P20813 BXGT008603 Cytochrome P450 2B6 1555 reviewed
P20815 BXGT008604 Cytochrome P450 3A5 1577 reviewed Enzyme
P21583 BXGT008667 Kit ligand 4254 reviewed
P22309 BXGT008753 UDP-glucuronosyltransferase 1-1 54658 reviewed
P23945 BXGT008931 Follicle-stimulating hormone receptor 2492 reviewed G-protein coupled receptor
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase 328 reviewed
P28331 BXGT009252 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial 4719 reviewed Enzyme
P28347 BXGT009257 Transcriptional enhancer factor TEF-1 7003 reviewed Transcription factor
P31260 BXGT009519 Homeobox protein Hox-A10 3206 reviewed
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P54577 BXGT011055 Tyrosine--tRNA ligase, cytoplasmic 8565 reviewed Enzyme
P78358 BXGT011838 Cancer/testis antigen 1 246100 reviewed
P78396 BXGT011842 Cyclin-A1 8900 reviewed Enzyme modulator
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13427 BXGT013354 Peptidyl-prolyl cis-trans isomerase G 9360 reviewed
Q13501 BXGT013365 Sequestosome-1 8878 reviewed
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q14573 BXGT013486 Inositol 1,4,5-trisphosphate receptor type 3 3710 reviewed Ion channel
Q15149 BXGT013547 Plectin 5339 reviewed Cellular structure
Q15831 BXGT013604 Serine/threonine-protein kinase STK11 6794 reviewed Kinase
Q16611 BXGT013644 Bcl-2 homologous antagonist/killer 578 reviewed Signaling
Q8WXD0 BXGT019009 Relaxin receptor 2 122042 reviewed G-protein coupled receptor
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q9HCR9 BXGT020537 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 50940 reviewed
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 28234 reviewed Transporter
Q9NZJ5 BXGT021275 Eukaryotic translation initiation factor 2-alpha kinase 3 9451 reviewed Kinase
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
Q9Y4I1 BXGT022278 Unconventional myosin-Va 4644 reviewed Cellular structure
Q9Y5K2 BXGT022293 Kallikrein-4 9622 reviewed Enzyme
Q9Y6K1 BXGT022331 DNA (cytosine-5)-methyltransferase 3A 1788 reviewed
P24462 BXGT022674 Cytochrome P450 3A7 1551 reviewed
Q96RD7 BXGT025890 Pannexin-1 24145 reviewed Ion channel
P11836 BXGT025994 B-lymphocyte antigen CD20 931 reviewed Receptor
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease