Showing entry for Adenylate cyclase type 10


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019709
Protein NameAdenylate cyclase type 10
Uniport IdQ96PN6
GeneADCY10
Gene Id55811
DomainGuanylate_cyc
Pfam PF00211  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.4 Nucleotide metabolism hsa00230 Purine metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
3. Environmental Information Processing 3.2 Signal transduction hsa04024 cAMP signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04371 Apelin signaling pathway
5. Organismal Systems 5.10 Environmental adaptation hsa04713 Circadian entrainment
5. Organismal Systems 5.10 Environmental adaptation hsa04714 Thermogenesis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006171 cAMP biosynthetic process
Biological Process GO:0071241 cellular response to inorganic substance
Biological Process GO:0003351 epithelial cilium movement involved in extracellular fluid movement
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0007283 spermatogenesis
molecular function GO:0004016 adenylate cyclase activity
molecular function GO:0051117 ATPase binding
molecular function GO:0005524 ATP binding
molecular function GO:0071890 bicarbonate binding
molecular function GO:0000287 magnesium ion binding
molecular function GO:0030145 manganese ion binding
cellular component GO:0016324 apical plasma membrane
cellular component GO:0045178 basal part of cell
cellular component GO:0005929 cilium
cellular component GO:0005737 cytoplasm
cellular component GO:0005856 cytoskeleton
cellular component GO:0005829 cytosol
cellular component GO:0030425 dendrite
cellular component GO:0005576 extracellular region
cellular component GO:0030426 growth cone
cellular component GO:0005739 mitochondrion
cellular component GO:0043025 neuronal cell body
cellular component GO:0005634 nucleus
cellular component GO:0048471 perinuclear region of cytoplasm
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-5358351 Signaling by Hedgehog
R-HSA-5610787 Hedgehog 'off' state
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0003811 BXGD000222 Cardiac Arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0005944 BXGD000355 Metabolic Bone Disorder Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007766 BXGD000478 Intracranial Aneurysm Nervous System Diseases; Cardiovascular Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011884 BXGD000762 Diabetic Retinopathy Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0017601 BXGD001125 Glaucoma Eye Diseases
C0017638 BXGD001132 Glioma Neoplasms
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0020438 BXGD001382 Hypercalciuria Pathological Conditions, Signs and Symptoms
C0023267 BXGD001626 Fibroid Tumor Neoplasms
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0035309 BXGD002530 Retinal Diseases Eye Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0039144 BXGD002796 Syringomyelia Nervous System Diseases
C0039147 BXGD002797 Syrinx formation
C0042133 BXGD002960 Uterine Fibroids Neoplasms
C0150055 BXGD003401 Chronic pain Pathological Conditions, Signs and Symptoms
C0162871 BXGD003996 Aortic Aneurysm, Abdominal Cardiovascular Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0231779 BXGD004521 Heel toe gait
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0342639 BXGD007518 Familial idiopathic hypercalciuria Pathological Conditions, Signs and Symptoms
C0345407 BXGD007736 OSTEOPETROSIS, AUTOSOMAL RECESSIVE 3 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases; Male Urogenital Diseases; Nervous System Diseases
C0403823 BXGD008315 Asthenozoospermia Male Urogenital Diseases
C0403824 BXGD008316 Teratozoospermia Male Urogenital Diseases
C0543800 BXGD009294 Idiopathic hypercalciuria Pathological Conditions, Signs and Symptoms
C0546983 BXGD009353 Post-Concussion Syndrome Nervous System Diseases; Wounds and Injuries
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1833683 BXGD013938 NEPHROLITHIASIS, CALCIUM OXALATE Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2673441 BXGD017203 Renal calcium wasting
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C4048158 BXGD021890 Convulsions Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4272578 BXGD022330 Autosomal Recessive Osteopetrosis Musculoskeletal Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0000988 3' 5'-cyclic AMP 329.21
BXGC0002586 Calcium 40.08
BXGC0002588 Magnesium 24.31
BXGC0003705 Chloride 35.45
BXGC0004275 Acetaldehyde 44.05
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein