adisease

Showing entry for Convulsions

General Disease Information
BXGD Id	BXGD021890
Disease Name	Convulsions
Disease CUI Id	C4048158
MeSH Codes	C23 C10
Disease Class Name	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
Semantic Type	Sign or Symptom
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00429	BXGT003919	Dynamin-1-like protein	10059	reviewed	Enzyme modulator
O00519	BXGT003934	Fatty-acid amide hydrolase 1	2166	reviewed
O15151	BXGT004132	Protein Mdm4	4194	reviewed	Nucleic acid binding
O15496	BXGT004175	Group 10 secretory phospholipase A2	8399	reviewed	Enzyme
O43766	BXGT004622	Lipoyl synthase, mitochondrial	11019	reviewed
O60462	BXGT004876	Neuropilin-2	8828	reviewed
O60741	BXGT004897	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1	348980	reviewed
O76039	BXGT005171	Cyclin-dependent kinase-like 5	6792	reviewed	Kinase
O94811	BXGT005336	Tubulin polymerization-promoting protein	11076	reviewed	Cellular structure
P00750	BXGT005642	Tissue-type plasminogen activator	5327	reviewed	Enzyme
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01100	BXGT005727	Proto-oncogene c-Fos	2353	reviewed	Transcription factor
P01138	BXGT005738	Beta-nerve growth factor	4803	reviewed	Signaling
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01303	BXGT005748	Pro-neuropeptide Y	4852	reviewed	Signaling
P01308	BXGT005749	Insulin	3630	reviewed
P01574	BXGT005768	Interferon beta	3456	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04054	BXGT006136	Phospholipase A2	5319	reviewed	Enzyme
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P05108	BXGT006317	Cholesterol side-chain cleavage enzyme, mitochondrial	1583	reviewed
P05181	BXGT006337	Cytochrome P450 2E1	1571	reviewed
P05186	BXGT006338	Alkaline phosphatase, tissue-nonspecific isozyme	249	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05771	BXGT006384	Protein kinase C beta type	5579	reviewed	Kinase
P06276	BXGT006430	Cholinesterase	590	reviewed
P06850	BXGT006511	Corticoliberin	1392	reviewed	Signaling
P08034	BXGT006716	Gap junction beta-1 protein	2705	reviewed	Cell-cell junction
P08138	BXGT006729	Tumor necrosis factor receptor superfamily member 16	4804	reviewed	Receptor
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08908	BXGT006837	5-hydroxytryptamine receptor 1A	3350	reviewed	G-protein coupled receptor
P09038	BXGT006851	Fibroblast growth factor 2	2247	reviewed	Signaling
P09104	BXGT006856	Gamma-enolase	2026	reviewed	Enzyme
P10909	BXGT007630	Clusterin	1191	reviewed
P11166	BXGT007661	Solute carrier family 2, facilitated glucose transporter member 1	6513	reviewed	Transporter
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	1128	reviewed	G-protein coupled receptor
P11413	BXGT007701	Glucose-6-phosphate 1-dehydrogenase	2539	reviewed	Enzyme
P13645	BXGT007936	Keratin, type I cytoskeletal 10	3858	reviewed
P13716	BXGT007948	Delta-aminolevulinic acid dehydratase	210	reviewed	Enzyme
P14416	BXGT008011	D(2) dopamine receptor	1813	reviewed	G-protein coupled receptor
P14555	BXGT008020	Phospholipase A2, membrane associated	5320	reviewed	Enzyme
P15884	BXGT008166	Transcription factor 4	6925	reviewed	Transcription factor
P16278	BXGT008213	Beta-galactosidase	2720	reviewed	Enzyme
P16389	BXGT008221	Potassium voltage-gated channel subfamily A member 2	3737	reviewed	Ion channel
P17252	BXGT008294	Protein kinase C alpha type	5578	reviewed	Kinase
P19021	BXGT008449	Peptidyl-glycine alpha-amidating monooxygenase	5066	reviewed	Enzyme
P20472	BXGT008578	Parvalbumin alpha	5816	reviewed	Calcium-binding protein
P21554	BXGT008662	Cannabinoid receptor 1	1268	reviewed	G-protein coupled receptor
P21728	BXGT008686	D(1A) dopamine receptor	1812	reviewed	G-protein coupled receptor
P22303	BXGT008751	Acetylcholinesterase	43	reviewed	Enzyme
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P23975	BXGT008935	Sodium-dependent noradrenaline transporter	6530	reviewed	Transporter
P24752	BXGT008993	Acetyl-CoA acetyltransferase, mitochondrial	38	reviewed	Enzyme
P25116	BXGT009025	Proteinase-activated receptor 1	2149	reviewed	G-protein coupled receptor
P25713	BXGT009062	Metallothionein-3	4504	reviewed
P27695	BXGT009199	DNA-(apurinic or apyrimidinic site) lyase	328	reviewed
P28222	BXGT009238	5-hydroxytryptamine receptor 1B	3351	reviewed	G-protein coupled receptor
P28329	BXGT009251	Choline O-acetyltransferase	1103	reviewed	Enzyme
P28907	BXGT009301	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	952	reviewed	Enzyme
P29218	BXGT009322	Inositol monophosphatase 1	3612	reviewed	Enzyme
P29274	BXGT009327	Adenosine receptor A2a	135	reviewed	G-protein coupled receptor
P29475	BXGT009353	Nitric oxide synthase, brain	4842	reviewed
P30531	BXGT009432	Sodium- and chloride-dependent GABA transporter 1	6529	reviewed	Transporter
P30532	BXGT009433	Neuronal acetylcholine receptor subunit alpha-5	1138	reviewed	Ion channel
P30874	BXGT009475	Somatostatin receptor type 2	6752	reviewed	G-protein coupled receptor
P30926	BXGT009482	Neuronal acetylcholine receptor subunit beta-4	1143	reviewed	Ion channel
P31644	BXGT009557	Gamma-aminobutyric acid receptor subunit alpha-5	2558	reviewed	Ion channel
P32297	BXGT009616	Neuronal acetylcholine receptor subunit alpha-3	1136	reviewed	Ion channel
P32418	BXGT009635	Sodium/calcium exchanger 1	6546	reviewed	Transporter
P33527	BXGT009728	Multidrug resistance-associated protein 1	4363	reviewed	Transporter
P34932	BXGT009772	Heat shock 70 kDa protein 4	3308	reviewed
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35368	BXGT009822	Alpha-1B adrenergic receptor	147	reviewed	G-protein coupled receptor
P35372	BXGT009823	Mu-type opioid receptor	4988	reviewed	G-protein coupled receptor
P35462	BXGT009835	D(3) dopamine receptor	1814	reviewed	G-protein coupled receptor
P35498	BXGT009838	Sodium channel protein type 1 subunit alpha	6323	reviewed	Ion channel
P37840	BXGT010015	Alpha-synuclein	6622	reviewed	Transporter
P39086	BXGT010093	Glutamate receptor ionotropic, kainate 1	2897	reviewed	Ion channel
P41145	BXGT010225	Kappa-type opioid receptor	4986	reviewed	G-protein coupled receptor
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P43005	BXGT010349	Excitatory amino acid transporter 3	6505	reviewed	Transporter
P43681	BXGT010407	Neuronal acetylcholine receptor subunit alpha-4	1137	reviewed	Ion channel
P45381	BXGT010460	Aspartoacylase	443	reviewed
P48735	BXGT010657	Isocitrate dehydrogenase [NADP], mitochondrial	3418	reviewed
P49798	BXGT010745	Regulator of G-protein signaling 4	5999	reviewed	Enzyme modulator
P51687	BXGT010882	Sulfite oxidase, mitochondrial	6821	reviewed
P54098	BXGT011030	DNA polymerase subunit gamma-1	5428	reviewed	Enzyme
P80188	BXGT011882	Neutrophil gelatinase-associated lipocalin	3934	reviewed	Enzyme
P80404	BXGT011907	4-aminobutyrate aminotransferase, mitochondrial	18	reviewed	Enzyme
Q05329	BXGT012814	Glutamate decarboxylase 2	2572	reviewed	Enzyme
Q05655	BXGT012832	Protein kinase C delta type	5580	reviewed	Kinase
Q12882	BXGT013276	Dihydropyrimidine dehydrogenase [NADP(+)]	1806	reviewed	Enzyme
Q14353	BXGT013463	Guanidinoacetate N-methyltransferase	2593	reviewed
Q14654	BXGT013495	ATP-sensitive inward rectifier potassium channel 11	3767	reviewed	Ion channel
Q15078	BXGT013534	Cyclin-dependent kinase 5 activator 1	8851	reviewed	Enzyme modulator
Q15139	BXGT013546	Serine/threonine-protein kinase D1	5587	reviewed	Kinase
Q5VZ30	BXGT015894	Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa)	2572	unreviewed
Q8N5H7	BXGT018518	SH2 domain-containing protein 3C	10044	reviewed
Q8TDS4	BXGT018812	Hydroxycarboxylic acid receptor 2	338442	reviewed
Q92887	BXGT019389	Canalicular multispecific organic anion transporter 1	1244	reviewed	Transporter
Q96FE5	BXGT019657	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1	84894	reviewed	Receptor
Q96PN6	BXGT019709	Adenylate cyclase type 10	55811	reviewed
Q96T60	BXGT019745	Bifunctional polynucleotide phosphatase/kinase	11284	reviewed
Q99572	BXGT019935	P2X purinoceptor 7	5027	reviewed	Ion channel
Q99720	BXGT019955	Sigma non-opioid intracellular receptor 1	10280	reviewed
Q9H2X9	BXGT020459	Solute carrier family 12 member 5	57468	reviewed	Transporter
Q9H4B4	BXGT020474	Serine/threonine-protein kinase PLK3	1263	reviewed	Kinase
Q9H8M5	BXGT020496	Metal transporter CNNM2	54805	reviewed
Q9NWB1	BXGT021231	RNA binding protein fox-1 homolog 1	54715	reviewed	Nucleic acid binding
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
O95140	BXGT024482	Mitofusin-2	9927	reviewed	Enzyme
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}