Showing entry for CCA tRNA nucleotidyltransferase 1, mitochondrial


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019713
Protein NameCCA tRNA nucleotidyltransferase 1, mitochondrial
Uniport IdQ96Q11
GeneTRNT1
Gene Id51095
DomainPolyA_pol; PolyA_pol_RNAbd
Pfam PF01743   PF12627  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.2 Translation hsa03013 RNA transport
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:1990180 mitochondrial tRNA 3'-end processing
Biological Process GO:0042780 tRNA 3'-end processing
Biological Process GO:0001680 tRNA 3'-terminal CCA addition
molecular function GO:0034062 5'-3' RNA polymerase activity
molecular function GO:0052929 ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity
molecular function GO:0005524 ATP binding
molecular function GO:0052928 CTP:3'-cytidine-tRNA cytidylyltransferase activity
molecular function GO:0052927 CTP:tRNA cytidylyltransferase activity
molecular function GO:0000049 tRNA binding
cellular component GO:0005622 intracellular
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0005739 mitochondrion
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
R-HSA-6784531 tRNA processing in the nucleus
R-HSA-6785470 tRNA processing in the mitochondrion
R-HSA-72306 tRNA processing
R-HSA-8953854 Metabolism of RNA
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0002891 BXGD000148 Anemia, Neonatal Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0002896 BXGD000153 Sideroblastic anemia Hemic and Lymphatic Diseases
C0013902 BXGD000865 Elliptocytosis, Hereditary Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0024312 BXGD001766 Lymphopenia Immune System Diseases; Hemic and Lymphatic Diseases
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0026946 BXGD001951 Mycoses Infections
C0027092 BXGD001971 Myopia Eye Diseases
C0028077 BXGD002069 Nyctalopia Eye Diseases
C0030232 BXGD002197 Pallor Pathological Conditions, Signs and Symptoms
C0035334 BXGD002539 Retinitis Pigmentosa Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0085576 BXGD003188 Iron-Refractory Iron Deficiency Anemia Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0086543 BXGD003294 Cataract Eye Diseases
C0221018 BXGD004366 Hereditary sideroblastic anemia Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0221278 BXGD004435 Anisocytosis
C0235988 BXGD004800 Serum iron low (finding) Nutritional and Metabolic Diseases
C0271901 BXGD006277 Microcytic hypochromic anemia (disorder) Hemic and Lymphatic Diseases
C0282193 BXGD006798 Iron Overload Nutritional and Metabolic Diseases
C0302254 BXGD006834 Juvenile cataract Eye Diseases
C0339543 BXGD007267 Epiretinal Membrane Eye Diseases
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0427480 BXGD008617 Elliptocytosis found
C0438434 BXGD008803 Scotoma, Ring Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0522274 BXGD009200 Humoral immune defect Immune System Diseases; Hemic and Lymphatic Diseases
C0554970 BXGD009428 Pallor of optic disc
C0557874 BXGD009444 Global developmental delay
C0836924 BXGD010864 Thrombocytosis Hemic and Lymphatic Diseases
C0854723 BXGD011026 Retinal Dystrophies Eye Diseases
C0855790 BXGD011088 Decreased mean corpuscular volume
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C1840457 BXGD014472 Retinal pigment epithelial atrophy
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1861403 BXGD016045 Variable expressivity
C2613439 BXGD017184 Extramedullary Hematopoiesis (disorder) Hemic and Lymphatic Diseases
C2698117 BXGD017446 Anisocyte Measurement
C4015172 BXGD020190 SIDEROBLASTIC ANEMIA WITH B-CELL IMMUNODEFICIENCY, PERIODIC FEVERS, AND DEVELOPMENTAL DELAY
C4048270 BXGD021897 Decreased antibody level in blood
C4073079 BXGD022035 Photoreceptor layer loss on macular OCT
C4310776 BXGD022660 RETINITIS PIGMENTOSA AND ERYTHROCYTIC MICROCYTOSIS
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein