adisease

Showing entry for Cataract

General Disease Information
BXGD Id	BXGD003294
Disease Name	Cataract
Disease CUI Id	C0086543
MeSH Codes	C11
Disease Class Name	Eye Diseases
Semantic Type	Acquired Abnormality
Human Phenotype Ontology Id	HP:0000478
Human Phenotype Ontology Term	Abnormality of the eye
Disease Ontology Id	DOID:630 DOID:7
Disease Ontology Class Name	genetic disease; disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A4D126	BXGT001208	D-ribitol-5-phosphate cytidylyltransferase	729920	reviewed
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O00429	BXGT003919	Dynamin-1-like protein	10059	reviewed	Enzyme modulator
O00444	BXGT003921	Serine/threonine-protein kinase PLK4	10733	reviewed	Kinase
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O14764	BXGT004094	Gamma-aminobutyric acid receptor subunit delta	2563	reviewed	Ion channel
O14832	BXGT004104	Phytanoyl-CoA dioxygenase, peroxisomal	5264	reviewed
O14936	BXGT004114	Peripheral plasma membrane protein CASK	8573	reviewed	Kinase
O15305	BXGT004152	Phosphomannomutase 2	5373	reviewed	Enzyme
O15527	BXGT004176	N-glycosylase/DNA lyase	4968	reviewed
O15553	BXGT004181	Pyrin	4210	reviewed
O43175	BXGT004575	D-3-phosphoglycerate dehydrogenase	26227	reviewed	Enzyme
O43464	BXGT004595	Serine protease HTRA2, mitochondrial	27429	reviewed
O43597	BXGT004602	Protein sprouty homolog 2	10253	reviewed	Signaling
O43683	BXGT004614	Mitotic checkpoint serine/threonine-protein kinase BUB1	699	reviewed	Kinase
O60313	BXGT004871	Dynamin-like 120 kDa protein, mitochondrial	4976	reviewed	Enzyme modulator
O60566	BXGT004884	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta	701	reviewed	Kinase
O60568	BXGT004885	Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3	8985	reviewed	Enzyme
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
O75369	BXGT005119	Filamin-B	2317	reviewed
O75530	BXGT005135	Polycomb protein EED	8726	reviewed
O75643	BXGT005142	U5 small nuclear ribonucleoprotein 200 kDa helicase	23020	reviewed
O95237	BXGT005361	Lecithin retinol acyltransferase	9227	reviewed
P00352	BXGT005510	Retinal dehydrogenase 1	216	reviewed	Enzyme
P00439	BXGT005539	Phenylalanine-4-hydroxylase	5053	reviewed
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P01023	BXGT005718	Alpha-2-macroglobulin	2	reviewed	Enzyme modulator
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01138	BXGT005738	Beta-nerve growth factor	4803	reviewed	Signaling
P01236	BXGT005744	Prolactin	5617	reviewed	Signaling
P01270	BXGT005746	Parathyroid hormone	5741	reviewed
P01308	BXGT005749	Insulin	3630	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02458	BXGT005879	Collagen alpha-1(II) chain	1280	reviewed
P02462	BXGT005881	Collagen alpha-1(IV) chain	1282	reviewed
P02511	BXGT005885	Alpha-crystallin B chain	1410	reviewed
P02538	BXGT005888	Keratin, type II cytoskeletal 6A	3853	reviewed
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02751	BXGT005943	Fibronectin	2335	reviewed	Signaling
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P02792	BXGT005966	Ferritin light chain	2512	reviewed	Storage
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P03886	BXGT006108	NADH-ubiquinone oxidoreductase chain 1	4535	reviewed	Enzyme
P03905	BXGT006113	NADH-ubiquinone oxidoreductase chain 4	4538	reviewed	Enzyme
P03915	BXGT006114	NADH-ubiquinone oxidoreductase chain 5	4540	reviewed	Enzyme
P03923	BXGT006115	NADH-ubiquinone oxidoreductase chain 6	4541	reviewed
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04264	BXGT006176	Keratin, type II cytoskeletal 1	3848	reviewed
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04792	BXGT006264	Heat shock protein beta-1	3315	reviewed
P05062	BXGT006305	Fructose-bisphosphate aldolase B	229	reviewed
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06280	BXGT006433	Alpha-galactosidase A	2717	reviewed
P06396	BXGT006435	Gelsolin	2934	reviewed	Cellular structure
P07339	BXGT006604	Cathepsin D	1509	reviewed	Enzyme
P07902	BXGT006697	Galactose-1-phosphate uridylyltransferase	2592	reviewed	Enzyme
P08100	BXGT006725	Rhodopsin	6010	reviewed	G-protein coupled receptor
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08235	BXGT006751	Mineralocorticoid receptor	4306	reviewed	Nuclear receptor
P08246	BXGT006756	Neutrophil elastase	1991	reviewed	Enzyme
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08572	BXGT006791	Collagen alpha-2(IV) chain	1284	reviewed
P08670	BXGT006810	Vimentin	7431	reviewed
P08779	BXGT006824	Keratin, type I cytoskeletal 16	3868	reviewed
P09038	BXGT006851	Fibroblast growth factor 2	2247	reviewed	Signaling
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P09486	BXGT006897	SPARC	6678	reviewed	Signaling
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P09651	BXGT006913	Heterogeneous nuclear ribonucleoprotein A1	3178	reviewed
P09936	BXGT006943	Ubiquitin carboxyl-terminal hydrolase isozyme L1	7345	reviewed	Enzyme
P0DMV8	BXGT007509	Heat shock 70 kDa protein 1A	3304	reviewed
P0DMV9	BXGT007510	Heat shock 70 kDa protein 1B	3304	reviewed
P0DN79	BXGT007511	Cystathionine beta-synthase-like protein	875	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10599	BXGT007583	Thioredoxin	7295	reviewed
P10600	BXGT007584	Transforming growth factor beta-3 proprotein	7043	reviewed	Signaling
P10745	BXGT007608	Retinol-binding protein 3	5949	reviewed
P10997	BXGT007643	Islet amyloid polypeptide	3375	reviewed	Signaling
P11166	BXGT007661	Solute carrier family 2, facilitated glucose transporter member 1	6513	reviewed	Transporter
P11413	BXGT007701	Glucose-6-phosphate 1-dehydrogenase	2539	reviewed	Enzyme
P11511	BXGT007717	Aromatase	1588	reviewed	Enzyme
P12004	BXGT007766	Proliferating cell nuclear antigen	5111	reviewed	Nucleic acid binding
P12081	BXGT007772	Histidine--tRNA ligase, cytoplasmic	3035	reviewed	Enzyme
P12235	BXGT007774	ADP/ATP translocase 1	291	reviewed	Transporter
P12271	BXGT007786	Retinaldehyde-binding protein 1	6017	reviewed	Transporter
P12724	BXGT007837	Eosinophil cationic protein	6037	reviewed
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13224	BXGT007890	Platelet glycoprotein Ib beta chain	2812	reviewed
P13236	BXGT007891	C-C motif chemokine 4	6351	reviewed
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P14679	BXGT008039	Tyrosinase	7299	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P14902	BXGT008065	Indoleamine 2,3-dioxygenase 1	3620	reviewed
P15121	BXGT008083	Aldo-keto reductase family 1 member B1	231	reviewed	Enzyme
P15289	BXGT008102	Arylsulfatase A	410	reviewed	Enzyme
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16109	BXGT008194	P-selectin	6403	reviewed
P16499	BXGT008238	Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	5145	reviewed
P17050	BXGT008277	Alpha-N-acetylgalactosaminidase	4668	reviewed
P17655	BXGT008325	Calpain-2 catalytic subunit	824	reviewed	Enzyme
P17707	BXGT008331	S-adenosylmethionine decarboxylase proenzyme	262	reviewed	Enzyme
P18074	BXGT008374	General transcription and DNA repair factor IIH helicase subunit XPD	2068	reviewed	Enzyme
P18075	BXGT008375	Bone morphogenetic protein 7	655	reviewed	Signaling
P18887	BXGT008437	DNA repair protein XRCC1	7515	reviewed
P19544	BXGT008494	Wilms tumor protein	7490	reviewed	Nucleic acid binding
P20794	BXGT008600	Serine/threonine-protein kinase MAK	4117	reviewed	Kinase
P20839	BXGT008608	Inosine-5'-monophosphate dehydrogenase 1	3614	reviewed	Enzyme
P20933	BXGT008618	N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	175	reviewed	Enzyme
P21266	BXGT008632	Glutathione S-transferase Mu 3	2947	reviewed
P21333	BXGT008638	Filamin-A	2316	reviewed
P21589	BXGT008669	5'-nucleotidase	4907	reviewed	Enzyme
P21709	BXGT008685	Ephrin type-A receptor 1	2041	reviewed	Kinase
P21964	BXGT008714	Catechol O-methyltransferase	1312	reviewed	Enzyme
P21980	BXGT008715	Protein-glutamine gamma-glutamyltransferase 2	7052	reviewed	Enzyme
P22626	BXGT008787	Heterogeneous nuclear ribonucleoproteins A2/B1	3181	reviewed
P22748	BXGT008802	Carbonic anhydrase 4	762	reviewed
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P23786	BXGT008906	Carnitine O-palmitoyltransferase 2, mitochondrial	1376	reviewed	Enzyme
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P26358	BXGT009104	DNA (cytosine-5)-methyltransferase 1	1786	reviewed	Epigenetic regulator
P27169	BXGT009161	Serum paraoxonase/arylesterase 1	5444	reviewed
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P27695	BXGT009199	DNA-(apurinic or apyrimidinic site) lyase	328	reviewed
P27986	BXGT009216	Phosphatidylinositol 3-kinase regulatory subunit alpha	5295	reviewed	Kinase
P28161	BXGT009234	Glutathione S-transferase Mu 2	2946	reviewed
P29033	BXGT009308	Gap junction beta-2 protein	2706	reviewed	Cell-cell junction
P29317	BXGT009331	Ephrin type-A receptor 2	1969	reviewed	Kinase
P29400	BXGT009343	Collagen alpha-5(IV) chain	1287	reviewed
P29466	BXGT009349	Caspase-1	834	reviewed	Enzyme
P29475	BXGT009353	Nitric oxide synthase, brain	4842	reviewed
P29973	BXGT009389	cGMP-gated cation channel alpha-1	1259	reviewed	Ion channel
P30041	BXGT009393	Peroxiredoxin-6	9588	reviewed	Enzyme
P30044	BXGT009395	Peroxiredoxin-5, mitochondrial	25824	reviewed
P30530	BXGT009431	Tyrosine-protein kinase receptor UFO	558	reviewed	Kinase
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P30838	BXGT009471	Aldehyde dehydrogenase, dimeric NADP-preferring	218	reviewed
P30988	BXGT009491	Calcitonin receptor	799	reviewed	G-protein coupled receptor
P31639	BXGT009556	Sodium/glucose cotransporter 2	6524	reviewed	Transporter
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P31785	BXGT009577	Cytokine receptor common subunit gamma	3561	reviewed	Signaling
P32019	BXGT009595	Type II inositol 1,4,5-trisphosphate 5-phosphatase	3633	reviewed	Enzyme
P34931	BXGT009771	Heat shock 70 kDa protein 1-like	3305	reviewed
P34932	BXGT009772	Heat shock 70 kDa protein 4	3308	reviewed
P35219	BXGT009797	Carbonic anhydrase-related protein	767	reviewed
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35442	BXGT009832	Thrombospondin-2	7058	reviewed
P35520	BXGT009842	Cystathionine beta-synthase	875	reviewed
P35555	BXGT009845	Fibrillin-1	2200	reviewed	Calcium-binding protein
P35579	BXGT009852	Myosin-9	4627	reviewed
P35869	BXGT009877	Aryl hydrocarbon receptor	196	reviewed	Transcription factor
P35913	BXGT009879	Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	5158	reviewed
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P37268	BXGT009975	Squalene synthase	2222	reviewed
P37840	BXGT010015	Alpha-synuclein	6622	reviewed	Transporter
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P39060	BXGT010088	Collagen alpha-1(XVIII) chain	80781	reviewed
P40337	BXGT010174	von Hippel-Lindau disease tumor suppressor	7428	reviewed	Enzyme
P40933	BXGT010209	Interleukin-15	3600	reviewed
P41161	BXGT010229	ETS translocation variant 5	2119	reviewed	Transcription factor
P41180	BXGT010230	Extracellular calcium-sensing receptor	846	reviewed	G-protein coupled receptor
P41227	BXGT010238	N-alpha-acetyltransferase 10	8260	reviewed	Enzyme
P41440	BXGT010261	Folate transporter 1	6573	reviewed	Transporter
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P43403	BXGT010385	Tyrosine-protein kinase ZAP-70	7535	reviewed	Kinase
P43652	BXGT010405	Afamin	173	reviewed	Transporter
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P46937	BXGT010554	Transcriptional coactivator YAP1	10413	reviewed	Enzyme modulator
P47712	BXGT010577	Cytosolic phospholipase A2	5321	reviewed	Enzyme
P48029	BXGT010606	Sodium- and chloride-dependent creatine transporter 1	6535	reviewed	Transporter
P48449	BXGT010632	Lanosterol synthase	4047	reviewed
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P49419	BXGT010705	Alpha-aminoadipic semialdehyde dehydrogenase	501	reviewed	Enzyme
P49585	BXGT010712	Choline-phosphate cytidylyltransferase A	5130	reviewed
P49768	BXGT010740	Presenilin-1	5663	reviewed	Enzyme
P49917	BXGT010765	DNA ligase 4	3981	reviewed
P50213	BXGT010779	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial	3419	reviewed	Enzyme
P50542	BXGT010808	Peroxisomal targeting signal 1 receptor	5830	reviewed	Transporter
P51532	BXGT010852	Transcription activator BRG1	6597	reviewed	Epigenetic regulator
P51570	BXGT010858	Galactokinase	2584	reviewed	Kinase
P51787	BXGT010889	Potassium voltage-gated channel subfamily KQT member 1	3784	reviewed	Ion channel
P51812	BXGT010893	Ribosomal protein S6 kinase alpha-3	6197	reviewed	Kinase
P51955	BXGT010908	Serine/threonine-protein kinase Nek2	4751	reviewed	Kinase
P52569	BXGT010934	Cationic amino acid transporter 2	6542	reviewed	Transporter
P52732	BXGT010948	Kinesin-like protein KIF11	3832	reviewed	Cellular structure
P52803	BXGT010958	Ephrin-A5	1946	reviewed	Signaling
P53667	BXGT011008	LIM domain kinase 1	3984	reviewed	Kinase
P53673	BXGT011010	Beta-crystallin A4	1413	reviewed
P54098	BXGT011030	DNA polymerase subunit gamma-1	5428	reviewed	Enzyme
P54132	BXGT011032	Bloom syndrome protein	641	reviewed
P54886	BXGT011092	Delta-1-pyrroline-5-carboxylate synthase	5832	reviewed	Enzyme
P55072	BXGT011103	Transitional endoplasmic reticulum ATPase	7415	reviewed
P55789	BXGT011126	FAD-linked sulfhydryl oxidase ALR	2671	reviewed	Enzyme
P60033	BXGT011286	CD81 antigen	975	reviewed
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P60568	BXGT011315	Interleukin-2	3558	reviewed
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P63000	BXGT011481	Ras-related C3 botulinum toxin substrate 1	5879	reviewed	Enzyme modulator
P63092	BXGT011495	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	2778	reviewed
P68871	BXGT011615	Hemoglobin subunit beta	3043	reviewed
P78417	BXGT011843	Glutathione S-transferase omega-1	9446	reviewed
P78504	BXGT011844	Protein jagged-1	182	reviewed
P82279	BXGT011972	Protein crumbs homolog 1	23418	reviewed
P98155	BXGT012226	Very low-density lipoprotein receptor	7436	reviewed
P98160	BXGT012228	Basement membrane-specific heparan sulfate proteoglycan core protein	3339	reviewed	Enzyme modulator
Q00604	BXGT012538	Norrin	4693	reviewed
Q00613	BXGT012540	Heat shock factor protein 1	3297	reviewed	Transcription factor
Q00796	BXGT012549	Sorbitol dehydrogenase	6652	reviewed	Enzyme
Q01831	BXGT012621	DNA repair protein complementing XP-C cells	7508	reviewed	Nucleic acid binding
Q01968	BXGT012626	Inositol polyphosphate 5-phosphatase OCRL-1	4952	reviewed	Enzyme
Q03164	BXGT012700	Histone-lysine N-methyltransferase 2A	4297	reviewed
Q03431	BXGT012714	Parathyroid hormone/parathyroid hormone-related peptide receptor	5745	reviewed	G-protein coupled receptor
Q03468	BXGT012716	DNA excision repair protein ERCC-6	2074	reviewed
Q04721	BXGT012777	Neurogenic locus notch homolog protein 2	4853	reviewed
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q06609	BXGT012884	DNA repair protein RAD51 homolog 1	5888	reviewed
Q08257	BXGT012975	Quinone oxidoreductase	1429	reviewed
Q09013	BXGT013023	Myotonin-protein kinase	1760	reviewed	Kinase
Q09472	BXGT013038	Histone acetyltransferase p300	2033	reviewed
Q12778	BXGT013263	Forkhead box protein O1	2308	reviewed
Q12830	BXGT013268	Nucleosome-remodeling factor subunit BPTF	2186	reviewed
Q12866	BXGT013273	Tyrosine-protein kinase Mer	10461	reviewed	Kinase
Q12918	BXGT013280	Killer cell lectin-like receptor subfamily B member 1	3820	reviewed
Q13233	BXGT013330	Mitogen-activated protein kinase kinase kinase 1	4214	reviewed	Kinase
Q13303	BXGT013336	Voltage-gated potassium channel subunit beta-2	8514	reviewed	Ion channel
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q13402	BXGT013348	Unconventional myosin-VIIa	4647	reviewed	Cellular structure
Q13485	BXGT013363	Mothers against decapentaplegic homolog 4	4089	reviewed	Transcription factor
Q14118	BXGT013444	Dystroglycan	1605	reviewed	Receptor
Q14145	BXGT013448	Kelch-like ECH-associated protein 1	9817	reviewed
Q14191	BXGT013452	Werner syndrome ATP-dependent helicase	7486	reviewed	Enzyme
Q14204	BXGT013456	Cytoplasmic dynein 1 heavy chain 1	1778	reviewed	Enzyme
Q14683	BXGT013500	Structural maintenance of chromosomes protein 1A	8243	reviewed
Q15109	BXGT013537	Advanced glycosylation end product-specific receptor	177	reviewed	Receptor
Q15125	BXGT013543	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	10682	reviewed	Enzyme
Q15126	BXGT013544	Phosphomevalonate kinase	10654	reviewed
Q15493	BXGT013575	Regucalcin	9104	reviewed	Enzyme
Q15582	BXGT013581	Transforming growth factor-beta-induced protein ig-h3	7045	reviewed	Signaling
Q15652	BXGT013587	Probable JmjC domain-containing histone demethylation protein 2C	221037	reviewed
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16595	BXGT013643	Frataxin, mitochondrial	2395	reviewed	Enzyme
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q16698	BXGT013659	2,4-dienoyl-CoA reductase, mitochondrial	1666	reviewed	Enzyme
Q16850	BXGT013681	Lanosterol 14-alpha demethylase	1595	reviewed	Enzyme
Q495M9	BXGT014765	Usher syndrome type-1G protein	124590	reviewed
Q53EZ4	BXGT015010	Centrosomal protein of 55 kDa	55165	reviewed
Q5VWK5	BXGT015891	Interleukin-23 receptor	149233	reviewed	Signaling
Q6P2Q9	BXGT016446	Pre-mRNA-processing-splicing factor 8	10594	reviewed	Nucleic acid binding
Q6PCD5	BXGT016464	E3 ubiquitin-protein ligase RFWD3	55159	reviewed	Enzyme
Q6XZF7	BXGT016615	Dynamin-binding protein	23268	reviewed
Q7LG56	BXGT016999	Ribonucleoside-diphosphate reductase subunit M2 B	50484	reviewed	Enzyme
Q7Z494	BXGT017254	Nephrocystin-3	27031	reviewed
Q86YC2	BXGT017633	Partner and localizer of BRCA2	79728	reviewed
Q8IVL5	BXGT018346	Prolyl 3-hydroxylase 2	55214	reviewed	Extracellular structure
Q8IWS0	BXGT018356	PHD finger protein 6	84295	reviewed	Nucleic acid binding
Q8IYD8	BXGT018367	Fanconi anemia group M protein	57697	reviewed	Enzyme
Q8NBK3	BXGT018538	Formylglycine-generating enzyme	285362	reviewed
Q8NBP7	BXGT018541	Proprotein convertase subtilisin/kexin type 9	255738	reviewed	Enzyme
Q8NCM8	BXGT018548	Cytoplasmic dynein 2 heavy chain 1	79659	reviewed	Enzyme
Q8NFD5	BXGT018560	AT-rich interactive domain-containing protein 1B	57492	reviewed
Q8NHU6	BXGT018569	Tudor domain-containing protein 7	23424	reviewed	Enzyme
Q8TCS8	BXGT018799	Polyribonucleotide nucleotidyltransferase 1, mitochondrial	87178	reviewed	Enzyme
Q8TD19	BXGT018804	Serine/threonine-protein kinase Nek9	91754	reviewed	Kinase
Q8WWY3	BXGT019006	U4/U6 small nuclear ribonucleoprotein Prp31	26121	reviewed	Nucleic acid binding
Q8WZA1	BXGT019024	Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1	55624	reviewed
Q92793	BXGT019374	CREB-binding protein	1387	reviewed
Q92834	BXGT019381	X-linked retinitis pigmentosa GTPase regulator	6103	reviewed
Q92843	BXGT019384	Bcl-2-like protein 2	599	reviewed	Signaling
Q969G3	BXGT019607	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1	6605	reviewed
Q96BZ9	BXGT019629	TBC1 domain family member 20	128637	reviewed
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q96NR8	BXGT019701	Retinol dehydrogenase 12	145226	reviewed	Enzyme
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q96Q11	BXGT019713	CCA tRNA nucleotidyltransferase 1, mitochondrial	51095	reviewed
Q96QU1	BXGT019721	Protocadherin-15	65217	reviewed
Q96RE7	BXGT019725	Nucleus accumbens-associated protein 1	112939	reviewed
Q99519	BXGT019928	Sialidase-1	4758	reviewed	Enzyme
Q99757	BXGT019959	Thioredoxin, mitochondrial	25828	reviewed	Enzyme
Q9BQ65	BXGT020107	U6 snRNA phosphodiesterase	79650	reviewed
Q9BVA1	BXGT020142	Tubulin beta-2B chain	347733	reviewed
Q9BY41	BXGT020180	Histone deacetylase 8	55869	reviewed	Epigenetic regulator
Q9C0B1	BXGT020209	Alpha-ketoglutarate-dependent dioxygenase FTO	79068	reviewed
Q9GZZ9	BXGT020430	Ubiquitin-like modifier-activating enzyme 5	79876	reviewed	Enzyme
Q9H0F7	BXGT020435	ADP-ribosylation factor-like protein 6	84100	reviewed
Q9H251	BXGT020449	Cadherin-23	64072	reviewed
Q9H3H5	BXGT020461	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	1798	reviewed	Enzyme
Q9H3M7	BXGT020462	Thioredoxin-interacting protein	10628	reviewed
Q9H4Y5	BXGT020479	Glutathione S-transferase omega-2	119391	reviewed
Q9H8P0	BXGT020497	Polyprenol reductase	79644	reviewed
Q9HBA0	BXGT020516	Transient receptor potential cation channel subfamily V member 4	59341	reviewed	Ion channel
Q9HC29	BXGT020526	Nucleotide-binding oligomerization domain-containing protein 2	64127	reviewed	Enzyme
Q9HCG7	BXGT020533	Non-lysosomal glucosylceramidase	57704	reviewed
Q9NP72	BXGT021144	Ras-related protein Rab-18	22931	reviewed
Q9NPD8	BXGT021152	Ubiquitin-conjugating enzyme E2 T	29089	reviewed
Q9NPI8	BXGT021161	Fanconi anemia group F protein	2188	reviewed
Q9NR56	BXGT021179	Muscleblind-like protein 1	4154	reviewed	Nucleic acid binding
Q9NRR6	BXGT021193	Phosphatidylinositol polyphosphate 5-phosphatase type IV	56623	reviewed
Q9NSE4	BXGT021207	Isoleucine--tRNA ligase, mitochondrial	55699	reviewed	Enzyme
Q9NW15	BXGT021229	Anoctamin-10	55129	reviewed
Q9NW38	BXGT021230	E3 ubiquitin-protein ligase FANCL	55120	reviewed	Enzyme
Q9NX14	BXGT021242	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial	54539	reviewed	Enzyme
Q9NZ08	BXGT021266	Endoplasmic reticulum aminopeptidase 1	51752	reviewed	Enzyme
Q9NZN9	BXGT021280	Aryl-hydrocarbon-interacting protein-like 1	23746	reviewed	Chaperone
Q9UBM7	BXGT021657	7-dehydrocholesterol reductase	1717	reviewed	Enzyme
Q9UI95	BXGT021714	Mitotic spindle assembly checkpoint protein MAD2B	10459	reviewed
Q9UJS0	BXGT021727	Calcium-binding mitochondrial carrier protein Aralar2	10165	reviewed	Transporter
Q9ULV1	BXGT021764	Frizzled-4	8322	reviewed	G-protein coupled receptor
Q9UMX1	BXGT021778	Suppressor of fused homolog	51684	reviewed
Q9UN36	BXGT021780	Protein NDRG2	57447	reviewed	Enzyme
Q9Y2Q3	BXGT022242	Glutathione S-transferase kappa 1	373156	reviewed
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
Q9Y2S2	BXGT022245	Lambda-crystallin homolog	51084	reviewed	Enzyme
Q9Y5X4	BXGT022306	Photoreceptor-specific nuclear receptor	10002	reviewed	Nuclear receptor
Q9Y617	BXGT022314	Phosphoserine aminotransferase	29968	reviewed
Q9Y6K9	BXGT022333	NF-kappa-B essential modulator	8517	reviewed	Kinase
Q9Y6N9	BXGT022337	Harmonin	10083	reviewed	Cellular structure
P04439	BXGT022649	HLA class I histocompatibility antigen, A-3 alpha chain	3105	reviewed
Q96KN7	BXGT022801	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1	57096	reviewed	Enzyme modulator
P00738	BXGT022874	Haptoglobin	3240	reviewed	Enzyme
P35240	BXGT022927	Merlin	4771	reviewed
P25054	BXGT022961	Adenomatous polyposis coli protein	324	reviewed
Q01543	BXGT023137	Friend leukemia integration 1 transcription factor	2313	reviewed	Transcription factor
O15467	BXGT023188	C-C motif chemokine 16	6360	reviewed	Signaling
Q01955	BXGT023255	Collagen alpha-3(IV) chain	1285	reviewed
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
Q92785	BXGT023424	Zinc finger protein ubi-d4	5977	reviewed	Enzyme
P00395	BXGT023596	Cytochrome c oxidase subunit 1	4512	reviewed	Enzyme
Q59FF6	BXGT023693	Excision repair cross-complementing rodent repair deficiency, complementation group 6 variant	2074	unreviewed
P56703	BXGT023722	Proto-oncogene Wnt-3	7473	reviewed	Signaling
Q99958	BXGT023732	Forkhead box protein C2	2303	reviewed	Transcription factor
P15260	BXGT023924	Interferon gamma receptor 1	3459	reviewed	Receptor
P07954	BXGT023939	Fumarate hydratase, mitochondrial	2271	reviewed	Enzyme
Q9UKP6	BXGT024239	Urotensin-2 receptor	2837	reviewed	G-protein coupled receptor
Q9ULV5	BXGT024442	Heat shock factor protein 4	3299	reviewed	Transcription factor
O95140	BXGT024482	Mitofusin-2	9927	reviewed	Enzyme
Q9H9S5	BXGT024623	Fukutin-related protein	79147	reviewed
O43837	BXGT024635	Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial	3420	reviewed	Enzyme
A6NHR9	BXGT024875	Structural maintenance of chromosomes flexible hinge domain-containing protein 1	23347	reviewed
Q13635	BXGT024910	Protein patched homolog 1	5727	reviewed
Q969H8	BXGT025606	Myeloid-derived growth factor	56005	reviewed
P28715	BXGT025675	DNA repair protein complementing XP-G cells	2073	reviewed
P35250	BXGT025854	Replication factor C subunit 2	5982	reviewed	Enzyme
Q86SQ9	BXGT025875	Dehydrodolichyl diphosphate synthase complex subunit DHDDS	79947	reviewed	Enzyme
Q9UQE7	BXGT025899	Structural maintenance of chromosomes protein 3	9126	reviewed
P58215	BXGT026106	Lysyl oxidase homolog 3	84695	reviewed
P07315	BXGT026109	Gamma-crystallin C	1420	reviewed
Q9UBS0	BXGT026113	Ribosomal protein S6 kinase beta-2	6199	reviewed	Kinase
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme
P07320	BXGT026150	Gamma-crystallin D	1421	reviewed
P43320	BXGT026151	Beta-crystallin B2	1415	reviewed
O43172	BXGT026158	U4/U6 small nuclear ribonucleoprotein Prp4	9128	reviewed	Nucleic acid binding
P02489	BXGT026168	Alpha-crystallin A chain	1409	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}