adisease

Showing entry for Thrombocytosis

General Disease Information
BXGD Id	BXGD010864
Disease Name	Thrombocytosis
Disease CUI Id	C0836924
MeSH Codes	C15
Disease Class Name	Hemic and Lymphatic Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0001871
Human Phenotype Ontology Term	Abnormality of blood and blood-forming tissues
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O15305	BXGT004152	Phosphomannomutase 2	5373	reviewed	Enzyme
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
O75844	BXGT005156	CAAX prenyl protease 1 homolog	10269	reviewed	Enzyme
P00519	BXGT005570	Tyrosine-protein kinase ABL1	25	reviewed	Kinase
P00734	BXGT005630	Prothrombin	2147	reviewed	Enzyme
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01909	BXGT005815	HLA class II histocompatibility antigen, DQ alpha 1 chain	3117	reviewed	Immune response
P01920	BXGT005817	HLA class II histocompatibility antigen, DQ beta 1 chain	3119	reviewed	Immune response
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02786	BXGT005961	Transferrin receptor protein 1	7037	reviewed	Enzyme
P04275	BXGT006180	von Willebrand factor	7450	reviewed	Enzyme modulator
P05109	BXGT006318	Protein S100-A8	6279	reviewed	Calcium-binding protein
P05231	BXGT006345	Interleukin-6	3569	reviewed
P07202	BXGT006565	Thyroid peroxidase	7173	reviewed	Enzyme
P07900	BXGT006696	Heat shock protein HSP 90-alpha	3320	reviewed	Chaperone
P08246	BXGT006756	Neutrophil elastase	1991	reviewed	Enzyme
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P09619	BXGT006911	Platelet-derived growth factor receptor beta	5159	reviewed	Kinase
P10275	BXGT007552	Androgen receptor	367	reviewed	Nuclear receptor
P11274	BXGT007681	Breakpoint cluster region protein	613	reviewed	Enzyme modulator
P11586	BXGT007723	C-1-tetrahydrofolate synthase, cytoplasmic	4522	reviewed	Enzyme
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P19971	BXGT008537	Thymidine phosphorylase	1890	reviewed	Enzyme
P21359	BXGT008640	Neurofibromin	4763	reviewed	Enzyme modulator
P22681	BXGT008795	E3 ubiquitin-protein ligase CBL	867	reviewed	Enzyme
P24752	BXGT008993	Acetyl-CoA acetyltransferase, mitochondrial	38	reviewed	Enzyme
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P30043	BXGT009394	Flavin reductase (NADPH)	645	reviewed	Enzyme
P35914	BXGT009880	Hydroxymethylglutaryl-CoA lyase, mitochondrial	3155	reviewed	Enzyme
P39019	BXGT010082	40S ribosomal protein S19	6223	reviewed	Nucleic acid binding
P40225	BXGT010168	Thrombopoietin	7066	reviewed
P48061	BXGT010616	Stromal cell-derived factor 1	6387	reviewed
P48729	BXGT010655	Casein kinase I isoform alpha	1452	reviewed	Kinase
P51692	BXGT010885	Signal transducer and activator of transcription 5B	6777	reviewed	Nucleic acid binding
P54136	BXGT011033	Arginine--tRNA ligase, cytoplasmic	5917	reviewed
P58335	BXGT011233	Anthrax toxin receptor 2	118429	reviewed	Receptor
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P68363	BXGT011594	Tubulin alpha-1B chain	10376	reviewed	Cellular structure
P68871	BXGT011615	Hemoglobin subunit beta	3043	reviewed
Q01196	BXGT012575	Runt-related transcription factor 1	861	reviewed	Transcription factor
Q02083	BXGT012633	N-acylethanolamine-hydrolyzing acid amidase	27163	reviewed	Enzyme
Q07812	BXGT012940	Apoptosis regulator BAX	581	reviewed	Signaling
Q15109	BXGT013537	Advanced glycosylation end product-specific receptor	177	reviewed	Receptor
Q5Y7D3	BXGT015912	HLA class II histocompatibility antigen DQ beta chain	3119	unreviewed
Q6GTX8	BXGT016315	Leukocyte-associated immunoglobulin-like receptor 1	3903	reviewed	Receptor
Q6N021	BXGT016378	Methylcytosine dioxygenase TET2	54790	reviewed
Q76LX8	BXGT016870	A disintegrin and metalloproteinase with thrombospondin motifs 13	11093	reviewed	Enzyme
Q86WV6	BXGT017626	Stimulator of interferon genes protein	340061	reviewed
Q96IY4	BXGT019678	Carboxypeptidase B2	1361	reviewed	Enzyme
Q96Q11	BXGT019713	CCA tRNA nucleotidyltransferase 1, mitochondrial	51095	reviewed
Q9H244	BXGT020448	P2Y purinoceptor 12	64805	reviewed	G-protein coupled receptor
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9UM73	BXGT021773	ALK tyrosine kinase receptor	238	reviewed	Kinase
Q9Y4D1	BXGT022273	Disheveled-associated activator of morphogenesis 1	23002	reviewed
P20036	BXGT022764	HLA class II histocompatibility antigen, DP alpha 1 chain	3113	reviewed	Immune response
P00738	BXGT022874	Haptoglobin	3240	reviewed	Enzyme
Q14678	BXGT023543	KN motif and ankyrin repeat domain-containing protein 1	23189	reviewed
P15260	BXGT023924	Interferon gamma receptor 1	3459	reviewed	Receptor
P62263	BXGT026033	40S ribosomal protein S14	6208	reviewed	Nucleic acid binding

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}