Showing entry for Cyclin-dependent kinase 19


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020156
Protein NameCyclin-dependent kinase 19
Uniport IdQ9BWU1
GeneCDK19
Gene Id23097
DomainPkinase
Pfam PF00069  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071222 cellular response to lipopolysaccharide
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0050729 positive regulation of inflammatory response
Biological Process GO:0006468 protein phosphorylation
molecular function GO:0005524 ATP binding
molecular function GO:0004693 cyclin-dependent protein serine/threonine kinase activity
molecular function GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity
cellular component GO:0005829 cytosol
cellular component GO:0016592 mediator complex
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-1266738 Developmental Biology
R-HSA-1266738 Developmental Biology
R-HSA-1430728 Metabolism
R-HSA-1989781 PPARA activates gene expression
R-HSA-381340 Transcriptional regulation of white adipocyte differentiation
R-HSA-381340 Transcriptional regulation of white adipocyte differentiation
R-HSA-400206 Regulation of lipid metabolism by PPARalpha
R-HSA-556833 Metabolism of lipids
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0019269 BXGD001310 Hermaphroditism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023827 BXGD001707 liposarcoma Neoplasms
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0026106 BXGD001889 Mild Mental Retardation Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0037369 BXGD002691 Smoking Behavior and Behavior Mechanisms
C0042133 BXGD002960 Uterine Fibroids Neoplasms
C0278608 BXGD006549 Adult Liposarcoma Neoplasms
C0279984 BXGD006703 Childhood Liposarcoma Neoplasms
C0346429 BXGD007828 Multiple malignancy Neoplasms
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1328504 BXGD012469 Hormone refractory prostate cancer Neoplasms; Male Urogenital Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1519383 BXGD013237 Smoking Behaviors Behavior and Behavior Mechanisms
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001545 Harmine 212.25
BXGC0040305 Indirubin 262.07
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein