Showing entry for Protein dpy-30 homolog



                       
General Target Information
BXGT IdBXGT020207
Protein NameProtein dpy-30 homolog
Uniport IdQ9C005
GeneDPY30
Gene Id84661
DomainDpy-30
Pfam PF05186  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006348 chromatin silencing at telomere
Biological Process GO:0016197 endosomal transport
Biological Process GO:0051568 histone H3-K4 methylation
Biological Process GO:0045652 regulation of megakaryocyte differentiation
molecular function GO:0042802 identical protein binding
molecular function GO:0042803 protein homodimerization activity
cellular component GO:0000781 chromosome, telomeric region
cellular component GO:0005794 Golgi apparatus
cellular component GO:0035097 histone methyltransferase complex
cellular component GO:0044666 MLL3/4 complex
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0048188 Set1C/COMPASS complex
cellular component GO:0005802 trans-Golgi network
Reactome
Pathway Id Pathway Name
R-HSA-212436 Generic Transcription Pathway
R-HSA-3214841 PKMTs methylate histone lysines
R-HSA-3247509 Chromatin modifying enzymes
R-HSA-4839726 Chromatin organization
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-74160 Gene expression (Transcription)
R-HSA-8878171 Transcriptional regulation by RUNX1
R-HSA-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002170 BXGD000105 Alopecia Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0005890 BXGD000345 Body Height
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0023418 BXGD001642 leukemia Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0029489 BXGD002163 Other alopecia Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0034152 BXGD002467 Henoch-Schoenlein Purpura Pathological Conditions, Signs and Symptoms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0037369 BXGD002691 Smoking Behavior and Behavior Mechanisms
C0037773 BXGD002704 Spastic Paraplegia, Hereditary Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0162311 BXGD003935 Androgenetic Alopecia Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0201657 BXGD004051 C-reactive protein measurement
C0206698 BXGD004248 Cholangiocarcinoma Neoplasms
C0220668 BXGD004317 Congenital contractural arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0279671 BXGD006677 Cervical Squamous Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0376545 BXGD008002 Hematologic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1519383 BXGD013237 Smoking Behaviors Behavior and Behavior Mechanisms
C1866855 BXGD016426 Spastic paraplegia 4, autosomal dominant Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2676272 BXGD017331 Alopecia, Androgenetic, 3 Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C2678038 BXGD017394 Alopecia, Androgenetic, 2 Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C2697766 BXGD017436 Interleukin 18 Measurement
C3711371 BXGD019381 Spastic Paraplegia Type 4 Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C3888194 BXGD019955 MIXED LINEAGE LEUKEMIA
C4049090 BXGD021913 Alopecia, Androgenetic, 1
C4083212 BXGD022105 Alopecia, Male Pattern Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0006368 Formic acid 46.03
BXGC0020706 Dithioerythritol 154.01
BXGC0028206 hexamethylene glycol 118.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein