Showing entry for Glutathione S-transferase omega-2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020479
Protein NameGlutathione S-transferase omega-2
Uniport IdQ9H4Y5
GeneGSTO2
Gene Id119391
DomainGST_N_3
Pfam PF13417  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.6 Metabolism of other amino acids hsa00480 Glutathione metabolism
1. Metabolism 1.11 Xenobiotics biodegradation and metabolism hsa00980 Metabolism of xenobiotics by cytochrome P450
1. Metabolism 1.11 Xenobiotics biodegradation and metabolism hsa00982 Drug metabolism - cytochrome P450
1. Metabolism 1.11 Xenobiotics biodegradation and metabolism hsa00983 Drug metabolism - other enzymes
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
6. Human Diseases 6.12 Drug resistance: Antineoplastic hsa01524 Platinum drug resistance
6. Human Diseases 6.1 Cancers: Overview hsa05200 Pathways in cancer
6. Human Diseases 6.1 Cancers: Overview hsa05204 Chemical carcinogenesis
6. Human Diseases 6.2 Cancers: Specific types hsa05225 Hepatocellular carcinoma
6. Human Diseases 6.6 Cardiovascular diseases hsa05418 Fluid shear stress and atherosclerosis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071243 cellular response to arsenic-containing substance
Biological Process GO:1901687 glutathione derivative biosynthetic process
Biological Process GO:0019852 L-ascorbic acid metabolic process
Biological Process GO:0055114 oxidation-reduction process
Biological Process GO:0006805 xenobiotic metabolic process
molecular function GO:0045174 glutathione dehydrogenase (ascorbate) activity
molecular function GO:0004364 glutathione transferase activity
molecular function GO:0042802 identical protein binding
molecular function GO:0050610 methylarsonate reductase activity
molecular function GO:0016491 oxidoreductase activity
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-156580 Phase II - Conjugation of compounds
R-HSA-156590 Glutathione conjugation
R-HSA-196836 Vitamin C (ascorbate) metabolism
R-HSA-196849 Metabolism of water-soluble vitamins and cofactors
R-HSA-196854 Metabolism of vitamins and cofactors
R-HSA-211859 Biological oxidations
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007138 BXGD000446 Carcinoma, Transitional Cell Neoplasms
C0008626 BXGD000559 Congenital chromosomal disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020676 BXGD001462 Hypothyroidism Endocrine System Diseases
C0023485 BXGD001667 Precursor B-Cell Lymphoblastic Leukemia-Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0036646 BXGD002627 Age-related cataract Eye Diseases
C0037284 BXGD002679 Skin lesion Skin and Connective Tissue Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0042341 BXGD002975 Varicocele Male Urogenital Diseases; Cardiovascular Diseases
C0086543 BXGD003294 Cataract Eye Diseases
C0202236 BXGD004086 Triglycerides measurement
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0279680 BXGD006680 Transitional cell carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0392557 BXGD008056 Nuclear cataract Eye Diseases
C0392885 BXGD008071 High density lipoprotein measurement
C0428472 BXGD008630 Serum HDL cholesterol measurement
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0577631 BXGD009535 Carotid Atherosclerosis Nervous System Diseases; Cardiovascular Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600327 BXGD009704 Toxic Shock Syndrome Pathological Conditions, Signs and Symptoms; Infections
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0752121 BXGD010669 Spinocerebellar Ataxia Type 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1112705 BXGD011681 Nuclear non-senile cataract Eye Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1292769 BXGD012230 Precursor B-cell lymphoblastic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1827293 BXGD013768 Carcinoma of urinary bladder, invasive Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1861305 BXGD016027 TARSAL-CARPAL COALITION SYNDROME Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C2145472 BXGD016931 Urothelial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2931852 BXGD018079 Clear-cell metastatic renal cell carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0000989 Glutathione 307.32
BXGC0003705 Chloride 35.45
BXGC0005685 Dehydroascorbic acid 174.11
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein