Showing entry for Clear-cell metastatic renal cell carcinoma


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD018079
Disease NameClear-cell metastatic renal cell carcinoma
Disease CUI IdC2931852
MeSH Codes C04   C13   C12  
Disease Class NameNeoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00755 BXGT003945 Protein Wnt-7a 7476 reviewed Signaling
O00767 BXGT003949 Acyl-CoA desaturase 6319 reviewed
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O14788 BXGT004100 Tumor necrosis factor ligand superfamily member 11 8600 reviewed Signaling
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O15550 BXGT004179 Lysine-specific demethylase 6A 7403 reviewed Epigenetic regulator
O43707 BXGT004616 Alpha-actinin-4 81 reviewed
O43791 BXGT004626 Speckle-type POZ protein 8405 reviewed
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O60494 BXGT004879 Cubilin 8029 reviewed
O75923 BXGT005166 Dysferlin 8291 reviewed Transporter
O96028 BXGT005417 Histone-lysine N-methyltransferase NSD2 7468 reviewed Epigenetic regulator
P01130 BXGT005735 Low-density lipoprotein receptor 3949 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P04075 BXGT006145 Fructose-bisphosphate aldolase A 226 reviewed
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06213 BXGT006425 Insulin receptor 3643 reviewed Kinase
P06870 BXGT006518 Kallikrein-1 3816 reviewed Enzyme
P07355 BXGT006609 Annexin A2 302 reviewed
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P08670 BXGT006810 Vimentin 7431 reviewed
P09486 BXGT006897 SPARC 6678 reviewed Signaling
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit 3815 reviewed Kinase
P10747 BXGT007609 T-cell-specific surface glycoprotein CD28 940 reviewed
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P11474 BXGT007710 Steroid hormone receptor ERR1 2101 reviewed Nuclear receptor
P13688 BXGT007943 Carcinoembryonic antigen-related cell adhesion molecule 1 634 reviewed
P14618 BXGT008027 Pyruvate kinase PKM 5315 reviewed Kinase
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P14902 BXGT008065 Indoleamine 2,3-dioxygenase 1 3620 reviewed
P15144 BXGT008087 Aminopeptidase N 290 reviewed Enzyme
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16070 BXGT008186 CD44 antigen 960 reviewed
P16234 BXGT008209 Platelet-derived growth factor receptor alpha 5156 reviewed Kinase
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P17936 BXGT008357 Insulin-like growth factor-binding protein 3 3486 reviewed Enzyme modulator
P19320 BXGT008470 Vascular cell adhesion protein 1 7412 reviewed
P19440 BXGT008481 Glutathione hydrolase 1 proenzyme 2678 reviewed Enzyme
P21589 BXGT008669 5'-nucleotidase 4907 reviewed Enzyme
P21860 BXGT008698 Receptor tyrosine-protein kinase erbB-3 2065 reviewed Kinase
P23193 BXGT008834 Transcription elongation factor A protein 1 6917 reviewed Nucleic acid binding
P23297 BXGT008848 Protein S100-A1 6271 reviewed Calcium-binding protein
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P24752 BXGT008993 Acetyl-CoA acetyltransferase, mitochondrial 38 reviewed Enzyme
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P28300 BXGT009243 Protein-lysine 6-oxidase 4015 reviewed
P29317 BXGT009331 Ephrin type-A receptor 2 1969 reviewed Kinase
P30518 BXGT009428 Vasopressin V2 receptor 554 reviewed G-protein coupled receptor
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35414 BXGT009829 Apelin receptor 187 reviewed G-protein coupled receptor
P35869 BXGT009877 Aryl hydrocarbon receptor 196 reviewed Transcription factor
P35916 BXGT009881 Vascular endothelial growth factor receptor 3 2324 reviewed Kinase
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P40261 BXGT010170 Nicotinamide N-methyltransferase 4837 reviewed Enzyme
P40337 BXGT010174 von Hippel-Lindau disease tumor suppressor 7428 reviewed Enzyme
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41235 BXGT010241 Hepatocyte nuclear factor 4-alpha 3172 reviewed Nuclear receptor
P41252 BXGT010245 Isoleucine--tRNA ligase, cytoplasmic 3376 reviewed Enzyme
P41279 BXGT010254 Mitogen-activated protein kinase kinase kinase 8 1326 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P42658 BXGT010327 Dipeptidyl aminopeptidase-like protein 6 1804 reviewed Enzyme
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P49789 BXGT010742 Bis(5'-adenosyl)-triphosphatase 2272 reviewed
P49862 BXGT010752 Kallikrein-7 5650 reviewed Enzyme
P50053 BXGT010769 Ketohexokinase 3795 reviewed Kinase
P51684 BXGT010880 C-C chemokine receptor type 6 1235 reviewed G-protein coupled receptor
P52292 BXGT010925 Importin subunit alpha-1 3838 reviewed Transporter
P53396 BXGT010988 ATP-citrate synthase 47 reviewed Enzyme
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P62508 BXGT011431 Estrogen-related receptor gamma 2104 reviewed Nuclear receptor
P78417 BXGT011843 Glutathione S-transferase omega-1 9446 reviewed
Q01650 BXGT012603 Large neutral amino acids transporter small subunit 1 8140 reviewed Transporter
Q01959 BXGT012624 Sodium-dependent dopamine transporter 6531 reviewed Transporter
Q02156 BXGT012639 Protein kinase C epsilon type 5581 reviewed Kinase
Q02763 BXGT012667 Angiopoietin-1 receptor 7010 reviewed Kinase
Q04609 BXGT012768 Glutamate carboxypeptidase 2 2346 reviewed Enzyme
Q06481 BXGT012878 Amyloid-like protein 2 334 reviewed Enzyme modulator
Q06710 BXGT012887 Paired box protein Pax-8 7849 reviewed
Q14118 BXGT013444 Dystroglycan 1605 reviewed Receptor
Q14571 BXGT013485 Inositol 1,4,5-trisphosphate receptor type 2 3709 reviewed Ion channel
Q14627 BXGT013492 Interleukin-13 receptor subunit alpha-2 3598 reviewed Signaling
Q15020 BXGT013522 Squamous cell carcinoma antigen recognized by T-cells 3 9733 reviewed Nucleic acid binding
Q15116 BXGT013539 Programmed cell death protein 1 5133 reviewed
Q15303 BXGT013557 Receptor tyrosine-protein kinase erbB-4 2066 reviewed Kinase
Q15369 BXGT013560 Elongin-C 6921 reviewed Enzyme modulator
Q15493 BXGT013575 Regucalcin 9104 reviewed Enzyme
Q15582 BXGT013581 Transforming growth factor-beta-induced protein ig-h3 7045 reviewed Signaling
Q15831 BXGT013604 Serine/threonine-protein kinase STK11 6794 reviewed Kinase
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16790 BXGT013670 Carbonic anhydrase 9 768 reviewed
Q7KZF4 BXGT016989 Staphylococcal nuclease domain-containing protein 1 27044 reviewed Transcription factor
Q86U86 BXGT017611 Protein polybromo-1 55193 reviewed Epigenetic regulator
Q8TCG1 BXGT018797 Protein CIP2A 57650 reviewed
Q92876 BXGT019388 Kallikrein-6 5653 reviewed Enzyme
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 1244 reviewed Transporter
Q96AC1 BXGT019617 Fermitin family homolog 2 10979 reviewed
Q96Q89 BXGT019716 Kinesin-like protein KIF20B 9585 reviewed Cellular structure
Q99683 BXGT019947 Mitogen-activated protein kinase kinase kinase 5 4217 reviewed Kinase
Q99814 BXGT019965 Endothelial PAS domain-containing protein 1 2034 reviewed Transcription factor
Q9BYW2 BXGT020192 Histone-lysine N-methyltransferase SETD2 29072 reviewed Epigenetic regulator
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9H4Y5 BXGT020479 Glutathione S-transferase omega-2 119391 reviewed
Q9NPH5 BXGT021159 NADPH oxidase 4 50507 reviewed Enzyme
Q9NTG7 BXGT021211 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 23410 reviewed Epigenetic regulator
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UH17 BXGT021691 DNA dC->dU-editing enzyme APOBEC-3B 9582 reviewed Enzyme
Q9UM73 BXGT021773 ALK tyrosine kinase receptor 238 reviewed Kinase
Q9UN36 BXGT021780 Protein NDRG2 57447 reviewed Enzyme
Q9UPN9 BXGT021799 E3 ubiquitin-protein ligase TRIM33 51592 reviewed
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
Q9Y6K1 BXGT022331 DNA (cytosine-5)-methyltransferase 3A 1788 reviewed
Q99958 BXGT023732 Forkhead box protein C2 2303 reviewed Transcription factor
P07954 BXGT023939 Fumarate hydratase, mitochondrial 2271 reviewed Enzyme
O60232 BXGT024169 Protein ZNRD2 10534 reviewed
Q92729 BXGT025605 Receptor-type tyrosine-protein phosphatase U 10076 reviewed Enzyme
P19532 BXGT026110 Transcription factor E3 7030 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease