Showing entry for Age-related cataract


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD002627
Disease NameAge-related cataract
Disease CUI IdC0036646
MeSH Codes C11  
Disease Class NameEye Diseases
Semantic TypeAcquired Abnormality
Human Phenotype Ontology Id HP:0000478  
Human Phenotype Ontology TermAbnormality of the eye
Disease Ontology Id DOID:630   DOID:7  
Disease Ontology Class Namegenetic disease; disease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O15527 BXGT004176 N-glycosylase/DNA lyase 4968 reviewed
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O75460 BXGT005127 Serine/threonine-protein kinase/endoribonuclease IRE1 2081 reviewed Kinase
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P01024 BXGT005719 Complement C3 718 reviewed Enzyme modulator
P02511 BXGT005885 Alpha-crystallin B chain 1410 reviewed
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02792 BXGT005966 Ferritin light chain 2512 reviewed Storage
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P07203 BXGT006566 Glutathione peroxidase 1 2876 reviewed Enzyme
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P0DMV8 BXGT007509 Heat shock 70 kDa protein 1A 3304 reviewed
P0DMV9 BXGT007510 Heat shock 70 kDa protein 1B 3304 reviewed
P11413 BXGT007701 Glucose-6-phosphate 1-dehydrogenase 2539 reviewed Enzyme
P14902 BXGT008065 Indoleamine 2,3-dioxygenase 1 3620 reviewed
P15311 BXGT008106 Ezrin 7430 reviewed Cellular structure
P18074 BXGT008374 General transcription and DNA repair factor IIH helicase subunit XPD 2068 reviewed Enzyme
P18848 BXGT008432 Cyclic AMP-dependent transcription factor ATF-4 468 reviewed
P18850 BXGT008433 Cyclic AMP-dependent transcription factor ATF-6 alpha 22926 reviewed
P18887 BXGT008437 DNA repair protein XRCC1 7515 reviewed
P21266 BXGT008632 Glutathione S-transferase Mu 3 2947 reviewed
P21709 BXGT008685 Ephrin type-A receptor 1 2041 reviewed Kinase
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase 328 reviewed
P28161 BXGT009234 Glutathione S-transferase Mu 2 2946 reviewed
P29317 BXGT009331 Ephrin type-A receptor 2 1969 reviewed Kinase
P30041 BXGT009393 Peroxiredoxin-6 9588 reviewed Enzyme
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P36955 BXGT009946 Pigment epithelium-derived factor 5176 reviewed Enzyme modulator
P36969 BXGT009949 Phospholipid hydroperoxide glutathione peroxidase 2879 reviewed Enzyme
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P48449 BXGT010632 Lanosterol synthase 4047 reviewed
P51570 BXGT010858 Galactokinase 2584 reviewed Kinase
P52803 BXGT010958 Ephrin-A5 1946 reviewed Signaling
P60568 BXGT011315 Interleukin-2 3558 reviewed
P78417 BXGT011843 Glutathione S-transferase omega-1 9446 reviewed
Q01831 BXGT012621 DNA repair protein complementing XP-C cells 7508 reviewed Nucleic acid binding
Q14145 BXGT013448 Kelch-like ECH-associated protein 1 9817 reviewed
Q14191 BXGT013452 Werner syndrome ATP-dependent helicase 7486 reviewed Enzyme
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16881 BXGT013688 Thioredoxin reductase 1, cytoplasmic 7296 reviewed Enzyme
Q8NHU6 BXGT018569 Tudor domain-containing protein 7 23424 reviewed Enzyme
Q92843 BXGT019384 Bcl-2-like protein 2 599 reviewed Signaling
Q969S2 BXGT019612 Endonuclease 8-like 2 252969 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q9H4Y5 BXGT020479 Glutathione S-transferase omega-2 119391 reviewed
Q9NNW7 BXGT021139 Thioredoxin reductase 2, mitochondrial 10587 reviewed Enzyme
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
Q9GZQ8 BXGT023414 Microtubule-associated proteins 1A/1B light chain 3B 81631 reviewed Cellular structure
Q9ULV5 BXGT024442 Heat shock factor protein 4 3299 reviewed Transcription factor
P07320 BXGT026150 Gamma-crystallin D 1421 reviewed
P43320 BXGT026151 Beta-crystallin B2 1415 reviewed
P02489 BXGT026168 Alpha-crystallin A chain 1409 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease