Showing entry for 5' exonuclease Apollo


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020494
Protein Name5' exonuclease Apollo
Uniport IdQ9H816
GeneDCLRE1B
Gene Id64858
DomainDRMBL
Pfam PF07522  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006303 double-strand break repair via nonhomologous end joining
Biological Process GO:0036297 interstrand cross-link repair
Biological Process GO:0007093 mitotic cell cycle checkpoint
Biological Process GO:0031848 protection from non-homologous end joining at telomere
Biological Process GO:0016233 telomere capping
Biological Process GO:0000723 telomere maintenance
Biological Process GO:0010833 telomere maintenance via telomere lengthening
Biological Process GO:0031860 telomeric 3' overhang formation
Biological Process GO:0031627 telomeric loop formation
molecular function GO:0035312 5'-3' exodeoxyribonuclease activity
molecular function GO:0008409 5'-3' exonuclease activity
molecular function GO:0003684 damaged DNA binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0042803 protein homodimerization activity
cellular component GO:0005813 centrosome
cellular component GO:0000781 chromosome, telomeric region
cellular component GO:0005737 cytoplasm
cellular component GO:0016604 nuclear body
cellular component GO:0000784 nuclear chromosome, telomeric region
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
R-HSA-6783310 Fanconi Anemia Pathway
R-HSA-73894 DNA Repair
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002726 BXGD000125 Amyloidosis Nutritional and Metabolic Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0008626 BXGD000559 Congenital chromosomal disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0015625 BXGD001006 Fanconi Anemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0017612 BXGD001129 Glaucoma, Open-Angle Eye Diseases
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0028840 BXGD002089 Ocular Hypertension Eye Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0152025 BXGD003521 Polyneuropathy Nervous System Diseases
C0184567 BXGD004039 Acute onset pain Pathological Conditions, Signs and Symptoms
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0259749 BXGD005216 Autonomic neuropathy Nervous System Diseases
C0268407 BXGD005936 Senile cardiac amyloidosis Nutritional and Metabolic Diseases; Cardiovascular Diseases
C0442874 BXGD008814 Neuropathy Nervous System Diseases
C0595921 BXGD009626 Intraocular pressure disorder Eye Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1148551 BXGD011766 X-Linked Dyskeratosis Congenita Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Hemic and Lymphatic Diseases
C1504336 BXGD013137 Polypoidal choroidal vasculopathy
C1846142 BXGD014785 HOYERAAL-HREIDARSSON SYNDROME Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Nervous System Diseases; Mental Disorders; Hemic and Lymphatic Diseases; Behavior and Behavior Mechanisms
C2751492 BXGD017718 AMYLOIDOSIS, HEREDITARY, TRANSTHYRETIN-RELATED Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C3469521 BXGD018910 FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000696 Tartaric acid 150.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein