Showing entry for Small conductance calcium-activated potassium channel protein 3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021681
Protein NameSmall conductance calcium-activated potassium channel protein 3
Uniport IdQ9UGI6
GeneKCNN3
Gene Id3782
DomainCaMBD; Ion_trans_2; SK_channel
Pfam PF02888   PF07885   PF03530  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.2 Endocrine system hsa04911 Insulin secretion
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006811 ion transport
Biological Process GO:0071805 potassium ion transmembrane transport
molecular function GO:0005516 calmodulin binding
molecular function GO:0016286 small conductance calcium-activated potassium channel activity
cellular component GO:0016021 integral component of membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0043005 neuron projection
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-112316 Neuronal System
R-HSA-1296052 Ca2+ activated K+ channels
R-HSA-1296071 Potassium Channels
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000846 BXGD000015 Agenesis
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0003125 BXGD000179 Anorexia Nervosa Mental Disorders
C0004134 BXGD000256 Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0005612 BXGD000317 Birth Weight Pathological Conditions, Signs and Symptoms
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007138 BXGD000446 Carcinoma, Transitional Cell Neoplasms
C0007193 BXGD000451 Cardiomyopathy, Dilated Cardiovascular Diseases
C0007758 BXGD000475 Cerebellar Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0019569 BXGD001337 Hirschsprung Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020541 BXGD001424 Portal Hypertension Digestive System Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0027126 BXGD001976 Myotonic Dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0033975 BXGD002447 Psychotic Disorders Mental Disorders
C0036337 BXGD002598 Schizoaffective Disorder Mental Disorders
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0038002 BXGD002723 Splenomegaly Pathological Conditions, Signs and Symptoms
C0042345 BXGD002977 Varicosity Cardiovascular Diseases
C0149931 BXGD003388 Migraine Disorders Nervous System Diseases
C0154830 BXGD003746 Proliferative diabetic retinopathy Pathological Conditions, Signs and Symptoms; Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0205682 BXGD004105 Waist-Hip Ratio
C0235480 BXGD004751 Paroxysmal atrial fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0338480 BXGD007186 Common Migraine Nervous System Diseases
C0340489 BXGD007336 Lone atrial fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0345905 BXGD007746 Intrahepatic Cholangiocarcinoma Neoplasms
C0349204 BXGD007892 Nonorganic psychosis Mental Disorders
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0740279 BXGD009973 Cerebellar atrophy
C0741276 BXGD010031 ATRIAL ENLARGEMENT
C0796013 BXGD010778 Zimmerman Laband syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1611743 BXGD013456 Familial (FPAH)
C1839839 BXGD014416 MAJOR AFFECTIVE DISORDER 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Mental Disorders
C1852197 BXGD015264 MAJOR AFFECTIVE DISORDER 1 Mental Disorders
C1865322 BXGD016313 MIGRAINE, FAMILIAL HEMIPLEGIC, 2 Nervous System Diseases
C1970943 BXGD016852 MAJOR AFFECTIVE DISORDER 4 Mental Disorders
C1970945 BXGD016853 MAJOR AFFECTIVE DISORDER 6 Mental Disorders
C2145472 BXGD016931 Urothelial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2585653 BXGD017139 Persistent atrial fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C2700438 BXGD017469 MAJOR AFFECTIVE DISORDER 7 Mental Disorders
C2700439 BXGD017470 MAJOR AFFECTIVE DISORDER 8 Mental Disorders
C2700440 BXGD017471 MAJOR AFFECTIVE DISORDER 9 Mental Disorders
C3468561 BXGD018908 familial atrial fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C4476912 BXGD022888 Idiopathic non-cirrhotic portal hypertension
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0042091 Dequalinium 456.33
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein