Showing entry for Cerebellar atrophy


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD009973
Disease NameCerebellar atrophy
Disease CUI IdC0740279
MeSH Codes   
Disease Class Name
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0000707  
Human Phenotype Ontology TermAbnormality of the nervous system
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A4D126 BXGT001208 D-ribitol-5-phosphate cytidylyltransferase 729920 reviewed
F7VJQ1 BXGT003310 Alternative prion protein 5621 reviewed
O00142 BXGT003883 Thymidine kinase 2, mitochondrial 7084 reviewed Kinase
O00189 BXGT003891 AP-4 complex subunit mu-1 9179 reviewed Extracellular structure
O00429 BXGT003919 Dynamin-1-like protein 10059 reviewed Enzyme modulator
O00444 BXGT003921 Serine/threonine-protein kinase PLK4 10733 reviewed Kinase
O00555 BXGT003936 Voltage-dependent P/Q-type calcium channel subunit alpha-1A 773 reviewed Ion channel
O00754 BXGT003944 Lysosomal alpha-mannosidase 4125 reviewed
O14773 BXGT004096 Tripeptidyl-peptidase 1 1200 reviewed Enzyme
O14936 BXGT004114 Peripheral plasma membrane protein CASK 8573 reviewed Kinase
O15305 BXGT004152 Phosphomannomutase 2 5373 reviewed Enzyme
O43181 BXGT004576 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial 4724 reviewed
O43424 BXGT004592 Glutamate receptor ionotropic, delta-2 2895 reviewed Ion channel
O43497 BXGT004596 Voltage-dependent T-type calcium channel subunit alpha-1G 8913 reviewed Ion channel
O43896 BXGT004632 Kinesin-like protein KIF1C 10749 reviewed Cellular structure
O60313 BXGT004871 Dynamin-like 120 kDa protein, mitochondrial 4976 reviewed Enzyme modulator
O60930 BXGT004910 Ribonuclease H1 246243 reviewed
O76039 BXGT005171 Cyclin-dependent kinase-like 5 6792 reviewed Kinase
O95363 BXGT005375 Phenylalanine--tRNA ligase, mitochondrial 10667 reviewed Enzyme
P00167 BXGT005473 Cytochrome b5 1528 reviewed Enzyme
P00387 BXGT005525 NADH-cytochrome b5 reductase 3 1727 reviewed
P02462 BXGT005881 Collagen alpha-1(IV) chain 1282 reviewed
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P04054 BXGT006136 Phospholipase A2 5319 reviewed Enzyme
P04156 BXGT006156 Major prion protein 5621 reviewed
P04350 BXGT006193 Tubulin beta-4A chain 10382 reviewed Cellular structure
P05129 BXGT006322 Protein kinase C gamma type 5582 reviewed Kinase
P07202 BXGT006565 Thyroid peroxidase 7173 reviewed Enzyme
P07333 BXGT006602 Macrophage colony-stimulating factor 1 receptor 1436 reviewed Kinase
P07339 BXGT006604 Cathepsin D 1509 reviewed Enzyme
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P09466 BXGT006892 Glycodelin 5047 reviewed Enzyme
P09936 BXGT006943 Ubiquitin carboxyl-terminal hydrolase isozyme L1 7345 reviewed Enzyme
P10636 BXGT007596 Microtubule-associated protein tau 4137 reviewed
P11712 BXGT007738 Cytochrome P450 2C9 1559 reviewed
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P12081 BXGT007772 Histidine--tRNA ligase, cytoplasmic 3035 reviewed Enzyme
P12235 BXGT007774 ADP/ATP translocase 1 291 reviewed Transporter
P13637 BXGT007933 Sodium/potassium-transporting ATPase subunit alpha-3 478 reviewed Transporter
P13639 BXGT007934 Elongation factor 2 1938 reviewed Enzyme
P18887 BXGT008437 DNA repair protein XRCC1 7515 reviewed
P19544 BXGT008494 Wilms tumor protein 7490 reviewed Nucleic acid binding
P21675 BXGT008678 Transcription initiation factor TFIID subunit 1 6872 reviewed Kinase
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P26640 BXGT009123 Valine--tRNA ligase 7407 reviewed
P28331 BXGT009252 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial 4719 reviewed Enzyme
P30566 BXGT009446 Adenylosuccinate lyase 158 reviewed Enzyme
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P35219 BXGT009797 Carbonic anhydrase-related protein 767 reviewed
P35398 BXGT009825 Nuclear receptor ROR-alpha 6095 reviewed Nuclear receptor
P35658 BXGT009859 Nuclear pore complex protein Nup214 8021 reviewed Nucleic acid binding
P39060 BXGT010088 Collagen alpha-1(XVIII) chain 80781 reviewed
P40926 BXGT010207 Malate dehydrogenase, mitochondrial 4191 reviewed Enzyme
P42858 BXGT010341 Huntingtin 3064 reviewed
P43003 BXGT010347 Excitatory amino acid transporter 1 6507 reviewed Transporter
P43155 BXGT010363 Carnitine O-acetyltransferase 1384 reviewed Enzyme
P49768 BXGT010740 Presenilin-1 5663 reviewed Enzyme
P49914 BXGT010762 5-formyltetrahydrofolate cyclo-ligase 10588 reviewed Enzyme
P49959 BXGT010766 Double-strand break repair protein MRE11 4361 reviewed
P51572 BXGT010859 B-cell receptor-associated protein 31 10134 reviewed Transporter
P54098 BXGT011030 DNA polymerase subunit gamma-1 5428 reviewed Enzyme
P54803 BXGT011082 Galactocerebrosidase 2581 reviewed
P57059 BXGT011210 Serine/threonine-protein kinase SIK1 150094 reviewed
P60953 BXGT011342 Cell division control protein 42 homolog 998 reviewed Enzyme modulator
P63104 BXGT011499 14-3-3 protein zeta/delta 7534 reviewed Chaperone
P78508 BXGT011845 ATP-sensitive inward rectifier potassium channel 10 3766 reviewed Ion channel
P98155 BXGT012226 Very low-density lipoprotein receptor 7436 reviewed
Q03154 BXGT012698 Aminoacylase-1 95 reviewed
Q03468 BXGT012716 DNA excision repair protein ERCC-6 2074 reviewed
Q06787 BXGT012890 Synaptic functional regulator FMR1 2332 reviewed Nucleic acid binding
Q09470 BXGT013037 Potassium voltage-gated channel subfamily A member 1 3736 reviewed Ion channel
Q12756 BXGT013261 Kinesin-like protein KIF1A 547 reviewed Cellular structure
Q12791 BXGT013264 Calcium-activated potassium channel subunit alpha-1 3778 reviewed Ion channel
Q13155 BXGT013320 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 7965 reviewed
Q13231 BXGT013329 Chitotriosidase-1 1118 reviewed
Q13255 BXGT013332 Metabotropic glutamate receptor 1 2911 reviewed G-protein coupled receptor
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13472 BXGT013360 DNA topoisomerase 3-alpha 7156 reviewed Enzyme
Q14003 BXGT013434 Potassium voltage-gated channel subfamily C member 3 3748 reviewed Ion channel
Q14108 BXGT013440 Lysosome membrane protein 2 950 reviewed Receptor
Q14643 BXGT013493 Inositol 1,4,5-trisphosphate receptor type 1 3708 reviewed Ion channel
Q15751 BXGT013593 Probable E3 ubiquitin-protein ligase HERC1 8925 reviewed Enzyme modulator
Q16512 BXGT013631 Serine/threonine-protein kinase N1 5585 reviewed Kinase
Q16595 BXGT013643 Frataxin, mitochondrial 2395 reviewed Enzyme
Q16795 BXGT013671 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial 4704 reviewed Enzyme
Q5JTZ9 BXGT015458 Alanine--tRNA ligase, mitochondrial 57505 reviewed Nucleic acid binding
Q6PI48 BXGT016471 Aspartate--tRNA ligase, mitochondrial 55157 reviewed Enzyme
Q7LG56 BXGT016999 Ribonucleoside-diphosphate reductase subunit M2 B 50484 reviewed Enzyme
Q7Z2E3 BXGT017246 Aprataxin 54840 reviewed Nucleic acid binding
Q86SZ2 BXGT017602 Trafficking protein particle complex subunit 6B 122553 reviewed
Q8IVA8 BXGT018342 Glutamate decarboxylase 1 (Brain, 67kDa) 2571 unreviewed
Q8NBK3 BXGT018538 Formylglycine-generating enzyme 285362 reviewed
Q8NI60 BXGT018572 Atypical kinase COQ8A, mitochondrial 56997 reviewed Kinase
Q92616 BXGT019358 eIF-2-alpha kinase activator GCN1 10985 reviewed Enzyme modulator
Q96BZ9 BXGT019629 TBC1 domain family member 20 128637 reviewed
Q96I59 BXGT019675 Probable asparagine--tRNA ligase, mitochondrial 79731 reviewed Enzyme
Q96IV0 BXGT019677 Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase 55768 reviewed Enzyme
Q96T60 BXGT019745 Bifunctional polynucleotide phosphatase/kinase 11284 reviewed
Q99250 BXGT019913 Sodium channel protein type 2 subunit alpha 6326 reviewed Ion channel
Q99259 BXGT019915 Glutamate decarboxylase 1 2571 reviewed Enzyme
Q99447 BXGT019922 Ethanolamine-phosphate cytidylyltransferase 5833 reviewed Enzyme
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q99757 BXGT019959 Thioredoxin, mitochondrial 25828 reviewed Enzyme
Q99798 BXGT019962 Aconitate hydratase, mitochondrial 50 reviewed Enzyme
Q9BQP7 BXGT020114 Mitochondrial genome maintenance exonuclease 1 92667 reviewed
Q9BVA1 BXGT020142 Tubulin beta-2B chain 347733 reviewed
Q9GZZ9 BXGT020430 Ubiquitin-like modifier-activating enzyme 5 79876 reviewed Enzyme
Q9H8P0 BXGT020497 Polyprenol reductase 79644 reviewed
Q9HCG7 BXGT020533 Non-lysosomal glucosylceramidase 57704 reviewed
Q9HD40 BXGT020542 O-phosphoseryl-tRNA(Sec) selenium transferase 51091 reviewed
Q9NP58 BXGT021143 ATP-binding cassette sub-family B member 6, mitochondrial 10058 reviewed Transporter
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 55775 reviewed Enzyme
Q9NW15 BXGT021229 Anoctamin-10 55129 reviewed
Q9NWX6 BXGT021238 Probable tRNA(His) guanylyltransferase 54974 reviewed
Q9NX46 BXGT021243 ADP-ribose glycohydrolase ARH3 54936 reviewed
Q9NY47 BXGT021249 Voltage-dependent calcium channel subunit alpha-2/delta-2 9254 reviewed Ion channel
Q9NZJ4 BXGT021274 Sacsin 26278 reviewed
Q9UGI6 BXGT021681 Small conductance calcium-activated potassium channel protein 3 3782 reviewed Ion channel
Q9UGM6 BXGT021687 Tryptophan--tRNA ligase, mitochondrial 10352 reviewed
Q9UHD2 BXGT021697 Serine/threonine-protein kinase TBK1 29110 reviewed Kinase
Q9UK17 BXGT021735 Potassium voltage-gated channel subfamily D member 3 3752 reviewed Ion channel
Q9UQD0 BXGT021811 Sodium channel protein type 8 subunit alpha 6334 reviewed Ion channel
Q9Y234 BXGT022211 Lipoyltransferase 1, mitochondrial 51601 reviewed Enzyme
Q9Y2Z4 BXGT022251 Tyrosine--tRNA ligase, mitochondrial 51067 reviewed Enzyme
Q9NYP7 BXGT022661 Elongation of very long chain fatty acids protein 5 60481 reviewed Enzyme
Q9Y5W7 BXGT022783 Sorting nexin-14 57231 reviewed Enzyme modulator
Q59FF6 BXGT023693 Excision repair cross-complementing rodent repair deficiency, complementation group 6 variant 2074 unreviewed
O75208 BXGT023882 Ubiquinone biosynthesis protein COQ9, mitochondrial 57017 reviewed
Q14657 BXGT024111 EKC/KEOPS complex subunit LAGE3 8270 reviewed
Q9NPF4 BXGT024113 Probable tRNA N6-adenosine threonylcarbamoyltransferase 55644 reviewed Enzyme
Q9H9S5 BXGT024623 Fukutin-related protein 79147 reviewed
Q9UNE7 BXGT025000 E3 ubiquitin-protein ligase CHIP 10273 reviewed
Q9Y4W6 BXGT025025 AFG3-like protein 2 10939 reviewed Enzyme
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
P46977 BXGT025531 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A 3703 reviewed Enzyme
Q8TCJ2 BXGT025533 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B 201595 reviewed Enzyme
P28715 BXGT025675 DNA repair protein complementing XP-G cells 2073 reviewed
Q6IQ55 BXGT025689 Tau-tubulin kinase 2 146057 reviewed Kinase
P35251 BXGT025853 Replication factor C subunit 1 5981 reviewed
P51798 BXGT026083 H(+)/Cl(-) exchange transporter 7 1186 reviewed Ion channel
P09471 BXGT026153 Guanine nucleotide-binding protein G(o) subunit alpha 2775 reviewed Enzyme modulator
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease