Showing entry for Protein SMG9


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT024746
Protein NameProtein SMG9
Uniport IdQ9H0W8
GeneSMG9
Gene Id56006
DomainSmg8_Smg9
Pfam PF10220  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007420 brain development
Biological Process GO:0001654 eye development
Biological Process GO:0007507 heart development
Biological Process GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
molecular function GO:0042802 identical protein binding
cellular component GO:0005829 cytosol
cellular component GO:0005622 intracellular
Reactome
Pathway Id Pathway Name
R-HSA-8953854 Metabolism of RNA
R-HSA-927802 Nonsense-Mediated Decay (NMD)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0008073 BXGD000518 Developmental Disabilities Mental Disorders
C0008924 BXGD000574 Cleft upper lip Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0010964 BXGD000692 Dandy-Walker Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0017168 BXGD001101 Gastroesophageal reflux disease Digestive System Diseases
C0018798 BXGD001223 Congenital Heart Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0018818 BXGD001236 Ventricular Septal Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0020224 BXGD001366 Polyhydramnios Female Urogenital Diseases and Pregnancy Complications
C0020534 BXGD001421 Orbital separation excessive Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0026010 BXGD001886 Microphthalmos Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0152419 BXGD003585 Interrupted aortic arch Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0162429 BXGD003942 Malnutrition Nutritional and Metabolic Diseases
C0235946 BXGD004789 Cerebral atrophy Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0239234 BXGD004974 Low set ears
C0239815 BXGD004996 Hand clenching
C0241816 BXGD005115 Global brain atrophy
C0344482 BXGD007678 Hypoplasia of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0409348 BXGD008384 Flexion contracture of proximal interphalangeal joint
C0424503 BXGD008532 Dysmorphic facies
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0431478 BXGD008692 Posteriorly rotated ear
C0456070 BXGD008863 Growth delay
C0557874 BXGD009444 Global developmental delay
C0857379 BXGD011148 Abnormality of the pinna
C1445953 BXGD013080 Poor eye contact Mental Disorders
C1836542 BXGD014129 Depressed nasal bridge
C1837260 BXGD014214 Prominent forehead
C1837404 BXGD014229 High, narrow palate
C1839739 BXGD014400 Thick lower lip vermilion
C1839758 BXGD014402 Narrow forehead
C1840077 BXGD014434 Anteverted nostril
C1846176 BXGD014791 Hyperactive deep tendon reflexes Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1849367 BXGD015046 Nasal bridge wide
C1853246 BXGD015323 Eversion of lower lip
C1853737 BXGD015356 Prominent occiput
C1853743 BXGD015358 Muscular hypotonia of the trunk Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1855677 BXGD015529 Brainstem dysplasia
C1857949 BXGD015758 Prominent metopic ridge
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1861866 BXGD016087 Aplasia/Hypoplasia of the corpus callosum
C1866134 BXGD016378 Wide anterior fontanel
C3665347 BXGD019279 Visual Impairment Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C4021758 BXGD020761 Delayed CNS myelination
C4049796 BXGD021951 Abnormality of cardiovascular system morphology Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C4310793 BXGD022669 HEART AND BRAIN MALFORMATION SYNDROME
C4528257 BXGD023159 Corpuscular Hemoglobin Concentration Mean
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0048845 Guanosine Triphosphate 522.99
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein