Showing entry for Flexion contracture of proximal interphalangeal joint


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD008384
Disease NameFlexion contracture of proximal interphalangeal joint
Disease CUI IdC0409348
MeSH Codes   
Disease Class Name
Semantic TypeFinding
Human Phenotype Ontology Id HP:0040064   HP:0000924   HP:0003549   HP:0003011  
Human Phenotype Ontology TermAbnormality of limbs; Abnormality of the skeletal system; Abnormality of connective tissue; Abnormality of the musculature
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O14764 BXGT004094 Gamma-aminobutyric acid receptor subunit delta 2563 reviewed Ion channel
O15119 BXGT004128 T-box transcription factor TBX3 6926 reviewed Transcription factor
O15146 BXGT004131 Muscle, skeletal receptor tyrosine-protein kinase 4593 reviewed Kinase
O43318 BXGT004586 Mitogen-activated protein kinase kinase kinase 7 6885 reviewed Kinase
O43929 BXGT004638 Origin recognition complex subunit 4 5000 reviewed Nucleic acid binding
O75496 BXGT005132 Geminin 51053 reviewed
O75530 BXGT005135 Polycomb protein EED 8726 reviewed
O75844 BXGT005156 CAAX prenyl protease 1 homolog 10269 reviewed Enzyme
O75899 BXGT005161 Gamma-aminobutyric acid type B receptor subunit 2 9568 reviewed G-protein coupled receptor
O76039 BXGT005171 Cyclin-dependent kinase-like 5 6792 reviewed Kinase
P00846 BXGT005674 ATP synthase subunit a 4508 reviewed Transporter
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P07510 BXGT006631 Acetylcholine receptor subunit gamma 1146 reviewed Ion channel
P11274 BXGT007681 Breakpoint cluster region protein 613 reviewed Enzyme modulator
P16144 BXGT008200 Integrin beta-4 3691 reviewed Receptor
P18074 BXGT008374 General transcription and DNA repair factor IIH helicase subunit XPD 2068 reviewed Enzyme
P21333 BXGT008638 Filamin-A 2316 reviewed
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P22314 BXGT008755 Ubiquitin-like modifier-activating enzyme 1 7317 reviewed Enzyme
P22607 BXGT008784 Fibroblast growth factor receptor 3 2261 reviewed Kinase
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P32004 BXGT009594 Neural cell adhesion molecule L1 3897 reviewed
P35475 BXGT009837 Alpha-L-iduronidase 3425 reviewed Enzyme
P35555 BXGT009845 Fibrillin-1 2200 reviewed Calcium-binding protein
P36021 BXGT009893 Monocarboxylate transporter 8 6567 reviewed Transporter
P36897 BXGT009941 TGF-beta receptor type-1 7046 reviewed Kinase
P37173 BXGT009970 TGF-beta receptor type-2 7048 reviewed Kinase
P41227 BXGT010238 N-alpha-acetyltransferase 10 8260 reviewed Enzyme
P41229 BXGT010239 Lysine-specific demethylase 5C 8242 reviewed
P42702 BXGT010335 Leukemia inhibitory factor receptor 3977 reviewed Signaling
P43026 BXGT010351 Growth/differentiation factor 5 8200 reviewed Signaling
P49773 BXGT010741 Histidine triad nucleotide-binding protein 1 3094 reviewed Enzyme
P58335 BXGT011233 Anthrax toxin receptor 2 118429 reviewed Receptor
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
Q01968 BXGT012626 Inositol polyphosphate 5-phosphatase OCRL-1 4952 reviewed Enzyme
Q01974 BXGT012628 Tyrosine-protein kinase transmembrane receptor ROR2 4920 reviewed Kinase
Q02127 BXGT012635 Dihydroorotate dehydrogenase (quinone), mitochondrial 1723 reviewed Enzyme
Q03468 BXGT012716 DNA excision repair protein ERCC-6 2074 reviewed
Q13303 BXGT013336 Voltage-gated potassium channel subunit beta-2 8514 reviewed Ion channel
Q13415 BXGT013350 Origin recognition complex subunit 1 4998 reviewed Nucleic acid binding
Q14332 BXGT013462 Frizzled-2 2535 reviewed G-protein coupled receptor
Q15022 BXGT013523 Polycomb protein SUZ12 23512 reviewed Nucleic acid binding
Q15465 BXGT013573 Sonic hedgehog protein 6469 reviewed
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q8NFD5 BXGT018560 AT-rich interactive domain-containing protein 1B 57492 reviewed
Q8WVQ1 BXGT018996 Soluble calcium-activated nucleotidase 1 124583 reviewed
Q92979 BXGT019402 Ribosomal RNA small subunit methyltransferase NEP1 10436 reviewed Nucleic acid binding
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q96S44 BXGT019738 EKC/KEOPS complex subunit TP53RK 112858 reviewed Kinase
Q9HBA0 BXGT020516 Transient receptor potential cation channel subfamily V member 4 59341 reviewed Ion channel
Q9HC29 BXGT020526 Nucleotide-binding oligomerization domain-containing protein 2 64127 reviewed Enzyme
Q9Y2I2 BXGT022236 Netrin-G1 22854 reviewed Enzyme modulator
Q9Y6K9 BXGT022333 NF-kappa-B essential modulator 8517 reviewed Kinase
Q59FF6 BXGT023693 Excision repair cross-complementing rodent repair deficiency, complementation group 6 variant 2074 unreviewed
Q14657 BXGT024111 EKC/KEOPS complex subunit LAGE3 8270 reviewed
Q9NPF4 BXGT024113 Probable tRNA N6-adenosine threonylcarbamoyltransferase 55644 reviewed Enzyme
Q96L73 BXGT024676 Histone-lysine N-methyltransferase, H3 lysine-36 specific 64324 reviewed Epigenetic regulator
Q9H0W8 BXGT024746 Protein SMG9 56006 reviewed
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
P28715 BXGT025675 DNA repair protein complementing XP-G cells 2073 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease