Showing entry for 4-Methylumbelliferyl acetate


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0005049
Compound Name4-Methylumbelliferyl acetate
Structure
FormulaC12H10O4
InchiKeyHXVZGASCDAGAPS-UHFFFAOYSA-N
SMILESCC(=O)OC1=CC=C2C(C)=CC(=O)OC2=C1
InchiInChI=1S/C12H10O4/c1-7-5-12(14)16-11-6-9(15-8(2)13)3-4-10(7)11/h3-6H,1-2H3
IUPAC4-methyl-2-oxo-2H-chromen-7-yl acetate
Molecular Weight218.21
Pubchem Id366
Chembl IdCHEMBL12019
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 33456
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT005640 Coagulation factor XII reviewed Enzyme F12 - >50000 - -
reviewed BXGT012285 dTDP-4-dehydrorhamnose 3,5-epimerase reviewed rmlC - 241 - -
CHEMBL CHEMBL12019
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P06280 BXGT006433 Alpha-galactosidase A reviewed - GLA Potency '=' 35481 nM
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 25118 nM
P10253 BXGT007550 Lysosomal alpha-glucosidase reviewed Enzyme GAA Potency '=' 35481 nM
O95149 BXGT005350 Snurportin-1 reviewed - SNUPN Potency - 125892 nM
Q14974 BXGT013516 Importin subunit beta-1 reviewed Transporter KPNB1 Potency - 125892 nM
P07943 BXGT006700 Aldo-keto reductase family 1 member B1 reviewed - Akr1b1 Inhibition '=' 13 %
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 3162 nM
P80244 BXGT011887 ATP-dependent Clp protease proteolytic subunit reviewed - clpP Potency - 25118 nM
P00748 BXGT005640 Coagulation factor XII reviewed Enzyme F12 IC50 '>' 50000 nM
P04062 BXGT006140 Lysosomal acid glucosylceramidase reviewed - GBA Potency - 19952 nM
O95149 BXGT005350 Snurportin-1 reviewed - SNUPN Potency - 20596 nM
Q14974 BXGT013516 Importin subunit beta-1 reviewed Transporter KPNB1 Potency - 20596 nM
P62826 BXGT011463 GTP-binding nuclear protein Ran reviewed Enzyme modulator RAN Potency - 20596 nM
P97697 BXGT012214 Inositol monophosphatase 1 reviewed - Impa1 Potency '=' 11220 nM
P23141 BXGT008830 Liver carboxylesterase 1 reviewed Enzyme CES1 Km '=' 800000 nM
P23141 BXGT008830 Liver carboxylesterase 1 reviewed Enzyme CES1 pKm '=' 3 -
B2RXH2 BXGT002006 Lysine-specific demethylase 4E reviewed - KDM4E Potency '=' 31622 nM
P02791 BXGT005965 Ferritin light chain reviewed - FTL Potency '=' 50118 nM
P06280 BXGT006433 Alpha-galactosidase A reviewed - GLA Potency - 35481 nM
P10253 BXGT007550 Lysosomal alpha-glucosidase reviewed Enzyme GAA Potency '=' 39810 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 5173 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00186 Fenugreek Trigonella foenum-graecum Herbs and Spices
BXGF00818 Herbs and Spices Herbs and Spices
BXGF00824 Green vegetables Vegetables
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease