acompound

Showing entry for 2,3-Dihydroxybenzoic acid

General Compound Information
BXGC Id	BXGC0005898
Compound Name	2,3-Dihydroxybenzoic acid
Structure
Formula	C7H6O4
InchiKey	GLDQAMYCGOIJDV-UHFFFAOYSA-N
SMILES	OC(=O)C1=C(O)C(O)=CC=C1
Inchi	InChI=1S/C7H6O4/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3,8-9H,(H,10,11)
IUPAC	2,3-dihydroxybenzoic acid
Molecular Weight	154.12
Pubchem Id	19
Chembl Id	CHEMBL1432

Targets of Information Source

DrugBank

DB01672

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
P40871	BXGT010204	2,3-dihydroxybenzoate-AMP ligase	reviewed	-	dhbE	experimental	-
P80188	BXGT011882	Neutrophil gelatinase-associated lipocalin	reviewed	Enzyme	LCN2	experimental	-

PDB

DBH

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P80188	BXGT011882	Neutrophil gelatinase-associated lipocalin	reviewed	LCN2	Enzyme	-	-	-	-
P80188	BXGT011882	Neutrophil gelatinase-associated lipocalin	reviewed	LCN2	Enzyme	-	-	7.9	-
P40871	BXGT010204	2,3-dihydroxybenzoate-AMP ligase	reviewed	dhbE	-	-	-	-	-
P21760	BXGT008689	Extracellular fatty acid-binding protein	reviewed	EXFABP	-	-	-	-	-
Q5EP34	BXGT015351	Polymerase acidic protein	unreviewed	PA	-	-	-	-	-

Binding DB

92456

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT013216	Alpha-(1,3)-fucosyltransferase 7	reviewed	Enzyme	FUT7	-	>200000	-	-
reviewed	BXGT008271	Prolyl 4-hydroxylase subunit alpha-1	reviewed		P4HA1	70000	-	-	-

CHEMBL

CHEMBL1432

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
Q969S8	BXGT019613	Polyamine deacetylase HDAC10	reviewed	Epigenetic regulator	HDAC10	Activity	'='	98	%
Q9UKV0	BXGT021750	Histone deacetylase 9	reviewed	Epigenetic regulator	HDAC9	Activity	'='	98	%
P56524	BXGT011176	Histone deacetylase 4	reviewed	Epigenetic regulator	HDAC4	Activity	'='	98	%
Q96DB2	BXGT019639	Histone deacetylase 11	reviewed	Epigenetic regulator	HDAC11	Activity	'='	98	%
Q9BY41	BXGT020180	Histone deacetylase 8	reviewed	Epigenetic regulator	HDAC8	Activity	'='	98	%
Q8WUI4	BXGT018992	Histone deacetylase 7	reviewed	Epigenetic regulator	HDAC7	Activity	'='	98	%
Q9UQL6	BXGT021813	Histone deacetylase 5	reviewed	Epigenetic regulator	HDAC5	Activity	'='	98	%
Q92769	BXGT019370	Histone deacetylase 2	reviewed	Epigenetic regulator	HDAC2	Activity	'='	98	%
Q9UBN7	BXGT021658	Histone deacetylase 6	reviewed	Epigenetic regulator	HDAC6	Activity	'='	98	%
O15379	BXGT004159	Histone deacetylase 3	reviewed	Epigenetic regulator	HDAC3	Activity	'='	98	%
Q13547	BXGT013373	Histone deacetylase 1	reviewed	Epigenetic regulator	HDAC1	Activity	'='	98	%
P14151	BXGT007990	L-selectin	reviewed	-	SELL	Inhibition	'='	1	%
P16581	BXGT008245	E-selectin	reviewed	-	SELE	Inhibition	'='	6	%
P02768	BXGT005955	Serum albumin	reviewed	Transporter	ALB	Activity	-	-	-
P14780	BXGT008053	Matrix metalloproteinase-9	reviewed	Enzyme	MMP9	Inhibition	'='	11	%
P08253	BXGT006757	72 kDa type IV collagenase	reviewed	Enzyme	MMP2	Inhibition	'='	-1	%
P09917	BXGT006941	Arachidonate 5-lipoxygenase	reviewed	Enzyme	ALOX5	Inhibition	'='	80	%
P29477	BXGT009355	Nitric oxide synthase, inducible	reviewed	-	Nos2	Inhibition	'='	2	%
P03956	BXGT006120	Interstitial collagenase	reviewed	Enzyme	MMP1	Inhibition	'='	17	%
P22894	BXGT008815	Neutrophil collagenase	reviewed	Enzyme	MMP8	Inhibition	'='	10	%
P16109	BXGT008194	P-selectin	reviewed	-	SELP	Inhibition	'='	-3	%
P08254	BXGT006758	Stromelysin-1	reviewed	Enzyme	MMP3	Inhibition	'='	-1	%
P15917	BXGT008169	Lethal factor	reviewed	-	lef	Inhibition	'='	9	%
Q9Y6L6	BXGT022334	Solute carrier organic anion transporter family member 1B1	reviewed	Transporter	SLCO1B1	Inhibition	'='	94	%
Q99700	BXGT019949	Ataxin-2	reviewed	Nucleic acid binding	ATXN2	Potency	-	44668	nM
O42713	BXGT004563	Polyphenol oxidase 2	reviewed	-	PPO2	Inhibition	'='	88	%
O75164	BXGT005104	Lysine-specific demethylase 4A	reviewed	-	KDM4A	Potency	-	100000	nM
Q9NPD5	BXGT021151	Solute carrier organic anion transporter family member 1B3	reviewed	Transporter	SLCO1B3	Inhibition	'='	84	%
P11137	BXGT007656	Microtubule-associated protein 2	reviewed	-	MAP2	Inhibition	'='	4	%
P05089	BXGT006310	Arginase-1	reviewed	Enzyme	ARG1	Inhibition	'='	82	%

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00006	Garden onion	Allium cepa	Vegetables
BXGF00008	Garlic	Allium sativum	Herbs and Spices
BXGF00013	Dill	Anethum graveolens	Herbs and Spices
BXGF00034	Broccoli	Brassica oleracea var. italica	Vegetables
BXGF00036	Turnip	Brassica rapa var. rapa	Herbs and Spices
BXGF00065	Cucumber	Cucumis sativus	Gourds
BXGF00120	Evening primrose	Oenothera biennis	Herbs and Spices
BXGF00171	Garden tomato	Solanum lycopersicum	Vegetables
BXGF00174	Eggplant	Solanum melongena	Vegetables
BXGF00192	American cranberry	Vaccinium macrocarpon	Fruits
BXGF00230	Carrot	Daucus carota ssp. sativus	Vegetables
BXGF00570	Grape wine		Beverages
BXGF00806	Alcoholic beverages		Beverages
BXGF00818	Herbs and Spices		Herbs and Spices
BXGF00825	Root vegetables		Vegetables
BXGF00827	Green zucchini	Cucurbita pepo var. cylindrica	Gourds
BXGF00829	Green bell pepper	Capsicum annuum	Vegetables
BXGF00830	Yellow bell pepper	Capsicum annuum	Vegetables
BXGF00833	Italian sweet red pepper	Capsicum annuum	Vegetables
BXGF00834	Yellow wax bean	Phaseolus vulgaris	Pulses
BXGF00838	Japanese pumpkin	Cucurbita maxima	Gourds
BXGF00840	Romaine lettuce	Lactuca sativa L. var. longifolia	Vegetables
BXGF01185	Aloe vera	Aloe vera	Medicinal Plant
BXGF01338	Amsinckia menziesii	Amsinckia menziesii	Others
BXGF01798	Melaleuca uncinata	Melaleuca uncinata	Others
BXGF01806	Rhododendron mucronatum	Rhododendron mucronatum	Medicinal Plant
BXGF01833	Hakea saligna	Hakea saligna	Others
BXGF01900	Aloe ferox	Aloe ferox	Medicinal Plant
BXGF02553	Avrainvillea nigricans	Avrainvillea nigricans	Others
BXGF02639	Rhododendron ferrugineum	Rhododendron ferrugineum	Human Edible Plant
BXGF02713	Drypetes roxburghii	Drypetes roxburghii	Medicinal Plant
BXGF02825	Buddleja variabilis	Buddleja variabilis	Others
BXGF02937	Senecio scandens	Senecio scandens	Medicinal Plant
BXGF03001	Vallaris solanacea	Vallaris solanacea	Medicinal Plant
BXGF03065	Mentha pulegiformis	Mentha pulegiformis	Others
BXGF03096	Salvia nubicola	Salvia nubicola	Human Edible Plant
BXGF03125	Grindelia nana	Grindelia nana	Others
BXGF03170	Haloxylon salicornicum	Haloxylon salicornicum	Medicinal Plant
BXGF03229	Leucanthemum maximum	Leucanthemum maximum	Others
BXGF03249	Vitex trifolia	Vitex trifolia	Medicinal Plant
BXGF03281	Calea megacephala	Calea megacephala	Others
BXGF03323	Abies nobilis	Abies nobilis	Others
BXGF03345	Persea indica	Persea indica	Medicinal Plant
BXGF03369	Corydalis cornuta	Corydalis cornuta	Others
BXGF03401	Disepalum plagioneurum	Disepalum plagioneurum	Others
BXGF03418	Piper aequale	Piper aequale	Medicinal Plant
BXGF03430	Alkanna hirsutissima	Alkanna hirsutissima	Others
BXGF03448	Pinus picea	Pinus picea	Others
BXGF03466	Picris radicata	Picris radicata	Others
BXGF03525	Acrocomia sclerocarpa	Acrocomia sclerocarpa	Others
BXGF03540	Eremophila serrulata	Eremophila serrulata	Others
BXGF03550	Rodgersia podophylla	Rodgersia podophylla	Medicinal Plant
BXGF03566	Delphinium campylocentrum	Delphinium campylocentrum	Others
BXGF03574	Cordyline indivisa	Cordyline indivisa	Medicinal Plant
BXGF03588	Primula hirsuta	Primula hirsuta	Others
BXGF03604	Jasminum grandiflorum	Jasminum grandiflorum	Medicinal Plant
BXGF03611	Viscum coloratum	Viscum coloratum	Medicinal Plant
BXGF04467	Aglaia odorata	Aglaia odorata	Medicinal Plant
BXGF04631	Aloe spicata	Aloe spicata	Medicinal Plant
BXGF04926	Aloe africana	Aloe africana	Medicinal Plant
BXGF05563	Phegopteris bukoensis	Phegopteris bukoensis	Others
BXGF05921	Scapania nemorea	Scapania nemorea	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}