Showing entry for Microtubule-associated protein 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT007656
Protein NameMicrotubule-associated protein 2
Uniport IdP11137
GeneMAP2
Gene Id4133
DomainMAP2_projctn; Tubulin-binding
Pfam PF08377   PF00418  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007409 axonogenesis
Biological Process GO:0071310 cellular response to organic substance
Biological Process GO:0021954 central nervous system neuron development
Biological Process GO:0016358 dendrite development
Biological Process GO:0048813 dendrite morphogenesis
Biological Process GO:0030010 establishment of cell polarity
Biological Process GO:0001578 microtubule bundle formation
Biological Process GO:0000226 microtubule cytoskeleton organization
Biological Process GO:0030517 negative regulation of axon extension
Biological Process GO:1904527 negative regulation of microtubule binding
Biological Process GO:2000575 negative regulation of microtubule motor activity
Biological Process GO:0031115 negative regulation of microtubule polymerization
Biological Process GO:0031175 neuron projection development
Biological Process GO:1901953 positive regulation of anterograde dense core granule transport
Biological Process GO:1903744 positive regulation of anterograde synaptic vesicle transport
Biological Process GO:1903827 regulation of cellular protein localization
Biological Process GO:0031113 regulation of microtubule polymerization
Biological Process GO:1902513 regulation of organelle transport along microtubule
molecular function GO:0005516 calmodulin binding
molecular function GO:0002162 dystroglycan binding
molecular function GO:0008017 microtubule binding
molecular function GO:0005198 structural molecule activity
molecular function GO:0048156 tau protein binding
cellular component GO:0150014 apical distal dendrite
cellular component GO:0043203 axon hillock
cellular component GO:0043194 axon initial segment
cellular component GO:0097441 basal dendrite
cellular component GO:0097442 CA3 pyramidal cell dendrite
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0030425 dendrite
cellular component GO:0032839 dendrite cytoplasm
cellular component GO:0044307 dendritic branch
cellular component GO:1902737 dendritic filopodium
cellular component GO:0044294 dendritic growth cone
cellular component GO:0043198 dendritic shaft
cellular component GO:0150002 distal dendrite
cellular component GO:0005874 microtubule
cellular component GO:0005875 microtubule associated complex
cellular component GO:0043025 neuronal cell body
cellular component GO:0043005 neuron projection
cellular component GO:0034399 nuclear periphery
cellular component GO:0014069 postsynaptic density
cellular component GO:0150001 primary dendrite
cellular component GO:1990635 proximal dendrite
cellular component GO:1990769 proximal neuron projection
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000786 BXGD000010 Spontaneous abortion Female Urogenital Diseases and Pregnancy Complications
C0000822 BXGD000012 Abortion, Tubal Female Urogenital Diseases and Pregnancy Complications
C0001849 BXGD000084 AIDS Dementia Complex Infections; Immune System Diseases; Nervous System Diseases; Mental Disorders
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002726 BXGD000125 Amyloidosis Nutritional and Metabolic Diseases
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0004045 BXGD000249 Asphyxia Neonatorum Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0004114 BXGD000255 Astrocytoma Neoplasms
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0004610 BXGD000281 Bacteremia Pathological Conditions, Signs and Symptoms; Infections
C0004941 BXGD000296 Behavioral Symptoms Behavior and Behavior Mechanisms
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0005890 BXGD000345 Body Height
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0007095 BXGD000423 Carcinoid Tumor Neoplasms
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007785 BXGD000485 Cerebral Infarction Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0007786 BXGD000486 Brain Ischemia Nervous System Diseases; Cardiovascular Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008479 BXGD000544 Chondrosarcoma Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0011265 BXGD000708 Presenile dementia Nervous System Diseases; Mental Disorders
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0014038 BXGD000878 Encephalitis Nervous System Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014474 BXGD000917 Ependymoma Neoplasms
C0014556 BXGD000932 Epilepsy, Temporal Lobe Nervous System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0017921 BXGD001152 Glycogen storage disease type II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0019569 BXGD001337 Hirschsprung Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020676 BXGD001462 Hypothyroidism Endocrine System Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023267 BXGD001626 Fibroid Tumor Neoplasms
C0024530 BXGD001783 Malaria Infections
C0025149 BXGD001826 Medulloblastoma Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0026640 BXGD001912 Mouth Neoplasms Neoplasms; Stomatognathic Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0027962 BXGD002064 Melanocytic nevus Neoplasms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0032019 BXGD002321 Pituitary Neoplasms Neoplasms; Nervous System Diseases; Endocrine System Diseases
C0034494 BXGD002481 Rabies (disorder) Infections
C0035126 BXGD002509 Reperfusion Injury Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0035372 BXGD002544 Rett Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0037278 BXGD002678 Skin Diseases, Infectious Infections; Skin and Connective Tissue Diseases
C0038220 BXGD002740 Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0038525 BXGD002768 Subarachnoid Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0041696 BXGD002932 Unipolar Depression Mental Disorders
C0042109 BXGD002957 Urticaria Skin and Connective Tissue Diseases; Immune System Diseases
C0042133 BXGD002960 Uterine Fibroids Neoplasms
C0086132 BXGD003264 Depressive Symptoms Behavior and Behavior Mechanisms
C0087031 BXGD003319 Juvenile-Onset Still Disease Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0149940 BXGD003391 Sciatic Neuropathy Nervous System Diseases
C0151779 BXGD003473 Cutaneous Melanoma Neoplasms; Skin and Connective Tissue Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0206663 BXGD004225 Neuroectodermal Tumor, Primitive Neoplasms
C0206695 BXGD004246 Carcinoma, Neuroendocrine Neoplasms
C0206715 BXGD004261 Neoplasms, Neuroepithelial Neoplasms
C0221232 BXGD004413 Welts Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases; Immune System Diseases
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0236734 BXGD004823 Caffeine related disorders
C0238339 BXGD004914 Hereditary pancreatitis Digestive System Diseases
C0242383 BXGD005160 Age related macular degeneration Eye Diseases
C0262584 BXGD005256 Carcinoma, Small Cell Neoplasms
C0278510 BXGD006526 Childhood Medulloblastoma Neoplasms
C0278874 BXGD006605 Adult Ependymoma Neoplasms
C0278876 BXGD006607 Adult Medulloblastoma Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0278883 BXGD006614 Metastatic melanoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0280483 BXGD006750 Adult Anaplastic Astrocytoma Neoplasms
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0333463 BXGD006954 Senile Plaques Pathological Conditions, Signs and Symptoms
C0334533 BXGD007105 Arteriovenous hemangioma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Cardiovascular Diseases
C0334579 BXGD007120 Anaplastic astrocytoma Neoplasms
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0424166 BXGD008521 Social Anxiety Behavior and Behavior Mechanisms
C0431380 BXGD008680 Cortical Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0431391 BXGD008683 Hemimegalencephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0497327 BXGD009061 Dementia Nervous System Diseases; Mental Disorders
C0521175 BXGD009134 Neuropil Threads
C0525045 BXGD009255 Mood Disorders Mental Disorders
C0542476 BXGD009276 Forgetful Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0740391 BXGD009987 Middle Cerebral Artery Occlusion Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0752308 BXGD010715 Hypoxia-Ischemia, Brain Nervous System Diseases; Cardiovascular Diseases
C0752347 BXGD010721 Lewy Body Disease Nervous System Diseases; Mental Disorders
C0796611 BXGD010835 Newly Diagnosed Childhood Ependymoma Neoplasms
C0878486 BXGD011364 Arteriolosclerosis Cardiovascular Diseases
C0949664 BXGD011583 Tauopathies Nervous System Diseases
C1096063 BXGD011600 Drug Resistant Epilepsy Nervous System Diseases
C1260954 BXGD011845 Morphologically altered structure
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1275278 BXGD012074 Extraskeletal Myxoid Chondrosarcoma Neoplasms
C1282983 BXGD012159 ehrlichiosis chafeensis (diagnosis) Infections
C1504404 BXGD013141 Hippocampal sclerosis
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1706731 BXGD013576 Adult Extraskeletal Myxoid Chondrosarcoma Neoplasms
C1851584 BXGD015221 Childhood Ependymoma Neoplasms
C2750737 BXGD017675 DIARRHEA 5, WITH TUFTING ENTEROPATHY, CONGENITAL Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Nutritional and Metabolic Diseases
C2936349 BXGD018109 Plaque, Amyloid Pathological Conditions, Signs and Symptoms
C3495559 BXGD018994 Juvenile arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C3665593 BXGD019294 Melanocytic nevus of skin Neoplasms
C3714758 BXGD019431 Juvenile psoriatic arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C3830362 BXGD019751 Early Pregnancy Loss Female Urogenital Diseases and Pregnancy Complications
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4551548 BXGD023342 Grade III Childhood Astrocytoma Neoplasms
C4552091 BXGD023485 Polyarthritis, Juvenile, Rheumatoid Factor Negative Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C4552766 BXGD023523 Miscarriage Female Urogenital Diseases and Pregnancy Complications
C4704862 BXGD023681 Polyarthritis, Juvenile, Rheumatoid Factor Positive Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C4721414 BXGD023738 Mantle cell lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0004556 1,2,3-Benzenetriol 126.11
BXGC0005898 2,3-Dihydroxybenzoic acid 154.12
BXGC0027421 Paclitaxel 853.33
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein