Showing entry for D-Tryptophan


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0019091
Compound NameD-Tryptophan
Structure
FormulaC11H12N2O2
InchiKeyQIVBCDIJIAJPQS-SECBINFHSA-N
SMILESOC(=O)[C@@H](Cc1c[nH]c2c1cccc2)N
InchiInChI=1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m1/s1
IUPAC(2R)-2-azaniumyl-3-(1H-indol-3-yl)propanoate
Molecular Weight204.09
Pubchem Id9060
Chembl IdCHEMBL292303
Targets of Information Source
DrugBank DB03225
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P14920 BXGT008067 D-amino-acid oxidase reviewed - DAO experimental -
PDB DTR
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P00371 BXGT005519 D-amino-acid oxidase reviewed DAO - - - - -
P58787 BXGT011250 Contryphan-Sm reviewed - - - - -
P58786 BXGT011249 Contryphan-R reviewed - - - - -
P80561 BXGT011917 Aminopeptidase S reviewed SGR_5809 - - - - -
P56254 BXGT011160 Kalata-B1 reviewed OAK1 - - - - -
P0C250 BXGT007407 Contryphan-Lo reviewed - - - - -
P95481 BXGT012158 Monodechloroaminopyrrolnitrin synthase PrnB reviewed prnB - - - - -
P02640 BXGT005907 Villin-1 reviewed VIL1 - - - - -
P01148 BXGT005739 Progonadoliberin-1 reviewed GNRH1 - - - - -
Q315G1 BXGT014312 Solute-binding protein Dde_0634 reviewed Dde_0634 - - - - -
O53512 BXGT004702 Phospho-2-dehydro-3-deoxyheptonate aldolase AroG reviewed aroG - - - 700000 -
O53512 BXGT004702 Phospho-2-dehydro-3-deoxyheptonate aldolase AroG reviewed aroG - - - - -
W4VSA0 BXGT023172 Contryphan-Vc2 reviewed - - - - -
P22629 BXGT008788 Streptavidin reviewed - - - - -
A0A493R6M6 BXGT023729 Cys-leu-gly-val-gly-ser-cys-val-asp-phe-ala-gly-cys-gly-tyr-ala-val-val-cys-phe-dtr unreviewed - - - - -
P01501 BXGT025041 Melittin reviewed MELT - - - - -
Binding DB 50043799
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT006758 Stromelysin-1 reviewed Enzyme MMP3 - >500000 - -
CHEMBL CHEMBL292303
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P08254 BXGT006758 Stromelysin-1 reviewed Enzyme MMP3 IC50 '>' 500000 nM
Q9ULX7 BXGT021769 Carbonic anhydrase 14 reviewed - CA14 KA '=' 18 uM
Q91Y77 BXGT019323 Monocarboxylate transporter 10 reviewed - Slc16a10 Activity - - -
P07451 BXGT006627 Carbonic anhydrase 3 reviewed - CA3 Ka '=' 19 uM
Q7RTX1 BXGT017089 Taste receptor type 1 member 1 reviewed G-protein coupled receptor TAS1R1 Activity - - -
Q7RTX0 BXGT017088 Taste receptor type 1 member 3 reviewed G-protein coupled receptor TAS1R3 Activity - - -
P40881 BXGT010205 Carbonic anhydrase reviewed - KA '=' 33 uM
Q13951 BXGT013407 Core-binding factor subunit beta reviewed - CBFB Potency - 39810 nM
Q01196 BXGT012575 Runt-related transcription factor 1 reviewed Transcription factor RUNX1 Potency - 39810 nM
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 Ka '=' 12 uM
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 Ka '=' 0 uM
P22748 BXGT008802 Carbonic anhydrase 4 reviewed - CA4 Ka '=' 40 uM
Q9Y2D0 BXGT022229 Carbonic anhydrase 5B, mitochondrial reviewed - CA5B Ka '=' 1 uM
P23280 BXGT008844 Carbonic anhydrase 6 reviewed - CA6 Ka '=' 39 uM
P22748 BXGT008802 Carbonic anhydrase 4 reviewed - CA4 Ka '=' 39 uM
P35218 BXGT009796 Carbonic anhydrase 5A, mitochondrial reviewed - CA5A Ka '=' 1 uM
P00915 BXGT005689 Carbonic anhydrase 1 reviewed - CA1 Ka '=' 41 uM
P42858 BXGT010341 Huntingtin reviewed - HTT Potency '=' 31622 nM
Q92830 BXGT019379 Histone acetyltransferase KAT2A reviewed - KAT2A Potency - 19952 nM
P43166 BXGT010364 Carbonic anhydrase 7 reviewed - CA7 Ka '=' 39 uM
Q16790 BXGT013670 Carbonic anhydrase 9 reviewed - CA9 Ka '=' 43 uM
Q9D6N1 BXGT020260 Carbonic anhydrase 13 reviewed - Ca13 Ka '=' 0 uM
Q16790 BXGT013670 Carbonic anhydrase 9 reviewed - CA9 KA '=' 43 uM
O43570 BXGT004601 Carbonic anhydrase 12 reviewed - CA12 KA '=' 28 uM
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 44668 nM
P53615 BXGT011003 Carbonic anhydrase reviewed - NCE103 Ka '=' 90 uM
Q6FTL6 BXGT016286 Carbonic anhydrase unreviewed - NCE103 Ka '=' 12 uM
Q50565 BXGT014936 Carbonic anhydrase unreviewed - MTH_1582 Ka '=' 41 uM
Q99N23 BXGT019994 Carbonic anhydrase 15 reviewed - Ca15 KA '=' 8 uM
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 33498 nM
P00915 BXGT005689 Carbonic anhydrase 1 reviewed - CA1 Kcat '=' 2 10'5/s
P43166 BXGT010364 Carbonic anhydrase 7 reviewed - CA7 KA '=' 39 uM
Q3I4V7 BXGT014421 Carbonic anhydrase unreviewed - CAN2 KA '=' 42 uM
Q5AJ71 BXGT015288 Carbonic anhydrase reviewed - NCE103 KA '=' 43 uM
O43570 BXGT004601 Carbonic anhydrase 12 reviewed - CA12 Ka '=' 28 uM
P25094 BXGT009014 Peripheral myelin protein 22 reviewed - Pmp22 Potency - 28695 nM
Q01650 BXGT012603 Large neutral amino acids transporter small subunit 1 reviewed Transporter SLC7A5 Activity '=' 81 %
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 Kcat '=' 6 10'5/s
P23280 BXGT008844 Carbonic anhydrase 6 reviewed - CA6 Kcat '=' 4 10'5/s
P49798 BXGT010745 Regulator of G-protein signaling 4 reviewed Enzyme modulator RGS4 Potency - 21192 nM
P02545 BXGT005889 Prelamin-A/C reviewed - LMNA Potency '=' 89 nM
Q4CVY4 BXGT026093 Carbonic anhydrase-like protein, putative unreviewed - Tc00.1047053509597.20 KA '=' 1 uM
O15648 BXGT004185 ATP-dependent 6-phosphofructokinase reviewed - pfk Potency - 11220 nM
Q01650 BXGT012603 Large neutral amino acids transporter small subunit 1 reviewed Transporter SLC7A5 Inhibition '=' 29 %
Q01650 BXGT012603 Large neutral amino acids transporter small subunit 1 reviewed Transporter SLC7A5 IC50 '=' 380000 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00008 Garlic Allium sativum Herbs and Spices
BXGF00027 Chinese mustard Brassica juncea Vegetables
BXGF00085 Soy bean Glycine max Soy
BXGF00337 Ginkgo nuts Ginkgo biloba Herbs and Spices
BXGF00369 Sacred lotus Nelumbo nucifera Vegetables
BXGF00380 White mustard Sinapis alba Herbs and Spices
BXGF01721 Humulus lupulus Humulus lupulus Medicinal Plant
BXGF02815 Pinellia ternata Pinellia ternata Medicinal Plant
BXGF04080 Persicaria orientalis Persicaria orientalis Medicinal Plant
BXGF05289 Allium macrostemon Allium macrostemon Medicinal Plant
BXGF05722 Hedysarum polybotrys Hedysarum polybotrys Medicinal Plant
BXGF06004 Allium chinense Allium chinense Medicinal Plant
BXGF06070 Perilla frutescens Perilla frutescens Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease