Showing entry for 1H-Indol-5-Ol


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0024132
Compound Name1H-Indol-5-Ol
Structure
FormulaC8H7NO
InchiKeyLMIQERWZRIFWNZ-UHFFFAOYSA-N
SMILESOc1ccc2c(c1)cc[nH]2
InchiInChI=1S/C8H7NO/c10-7-1-2-8-6(5-7)3-4-9-8/h1-5,9-10H
IUPAC1H-indol-5-ol
Molecular Weight133.05
Pubchem Id16054
Chembl IdCHEMBL404923
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB 5H1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P09960 BXGT006952 Leukotriene A-4 hydrolase reviewed LTA4H - - - - -
O74036 BXGT005082 DNA repair and recombination protein RadA reviewed radA - - - 1900000 -
P25321 BXGT009037 cAMP-dependent protein kinase catalytic subunit alpha reviewed PRKACA - - - - -
Binding DB 32212
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT006696 Heat shock protein HSP 90-alpha reviewed Chaperone HSP90AA1 - 50000 - -
reviewed BXGT006016 Large T antigen reviewed - - 80220 - -
reviewed BXGT005082 DNA repair and recombination protein RadA reviewed radA - - 2100000 -
reviewed BXGT006952 Leukotriene A-4 hydrolase reviewed LTA4H - >1000000 - -
reviewed BXGT012884 DNA repair protein RAD51 homolog 1 reviewed RAD51 - - 2100000 -
reviewed BXGT006952 Leukotriene A-4 hydrolase reviewed LTA4H - >2000000 - -
reviewed BXGT007687 Tyrosinase reviewed Tyr - 68000 - -
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 - - - 1000000
CHEMBL CHEMBL404923
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P16050 BXGT008184 Arachidonate 15-lipoxygenase reviewed Enzyme ALOX15 Potency '=' 10000 nM
Q06609 BXGT012884 DNA repair protein RAD51 homolog 1 reviewed - RAD51 Kd '=' 2100000 nM
P09960 BXGT006952 Leukotriene A-4 hydrolase reviewed - LTA4H IC50 '>' 2000000 nM
P09960 BXGT006952 Leukotriene A-4 hydrolase reviewed - LTA4H IC50 '>' 1000000 nM
P11344 BXGT007687 Tyrosinase reviewed - Tyr Activity '=' 62 %
P08238 BXGT006753 Heat shock protein HSP 90-beta reviewed Chaperone HSP90AB1 IC50 '>' 50000 nM
P07900 BXGT006696 Heat shock protein HSP 90-alpha reviewed Chaperone HSP90AA1 IC50 '>' 50000 nM
Q96QE3 BXGT019718 ATPase family AAA domain-containing protein 5 reviewed - ATAD5 Potency - 4466 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 EC50 '=' 1000000 nM
P14679 BXGT008039 Tyrosinase reviewed Enzyme TYR Activity '=' 54 %
P11344 BXGT007687 Tyrosinase reviewed - Tyr IC50 '=' 68000 nM
O75604 BXGT005139 Ubiquitin carboxyl-terminal hydrolase 2 reviewed Enzyme USP2 Potency '=' 7943 nM
P10253 BXGT007550 Lysosomal alpha-glucosidase reviewed Enzyme GAA Potency '=' 14125 nM
P03070 BXGT006016 Large T antigen reviewed - IC50 - 80220 nM
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 8199 nM
Q6W5P4 BXGT016588 Neuropeptide S receptor reviewed - NPSR1 Potency '=' 5011 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 %max '=' 541 %
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 16360 nM
O42275 BXGT004559 Acetylcholinesterase reviewed - ache Inhibition '=' 7 %
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF02792 Ligusticum sinense Ligusticum sinense Medicinal Plant
BXGF03379 Cnidium officinale Cnidium officinale Medicinal Plant
BXGF04982 Ligusticum chuanxiong Ligusticum chuanxiong Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease