Showing entry for L-Ido-1-Deoxynojirimycin


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0032319
Compound NameL-Ido-1-Deoxynojirimycin
Structure
FormulaC6H13NO4
InchiKeyLXBIFEVIBLOUGU-UNTFVMJOSA-N
SMILESOC[C@@H]1NC[C@@H]([C@H]([C@@H]1O)O)O
InchiInChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4-,5+,6+/m0/s1
IUPAC(2S,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol
Molecular Weight163.08
Pubchem Id10888248
Chembl IdCHEMBL175901
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 50312525
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT008009 Sucrase-isomaltase, intestinal reviewed Enzyme SI - 1000000 - -
reviewed BXGT013663 Ceramide glucosyltransferase reviewed Enzyme UGCG - 9000 - -
reviewed BXGT006929 Lactase-phlorizin hydrolase reviewed Enzyme LCT - >1000000 - -
reviewed BXGT020533 Non-lysosomal glucosylceramidase reviewed GBA2 - 400000 - -
reviewed BXGT007550 Lysosomal alpha-glucosidase reviewed Enzyme GAA - >1000000 - -
reviewed BXGT009850 Glycogen debranching enzyme reviewed Enzyme AGL - >100000 - -
reviewed BXGT004594 Maltase-glucoamylase, intestinal reviewed Enzyme MGAM - >1000000 - -
CHEMBL CHEMBL175901
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P06280 BXGT006433 Alpha-galactosidase A reviewed - GLA Inhibition '<' 50 %
P10253 BXGT007550 Lysosomal alpha-glucosidase reviewed Enzyme GAA IC50 '>' 1000000 nM
O43451 BXGT004594 Maltase-glucoamylase, intestinal reviewed Enzyme MGAM IC50 '>' 1000000 nM
P23739 BXGT008901 Sucrase-isomaltase, intestinal reviewed - Si Inhibition '<' 50 %
Q4FZV0 BXGT014807 Beta-mannosidase reviewed - Manba Inhibition '<' 50 %
Q9UUZ4 BXGT021832 Alpha-galactosidase C reviewed - aglC Inhibition '<' 50 %
Q9LGC6 BXGT021076 Putative alpha-glucosidase unreviewed - P0504H10.9 Inhibition '<' 50 %
P16278 BXGT008213 Beta-galactosidase reviewed Enzyme GLB1 Inhibition '<' 50 %
Q58D55 BXGT015223 Beta-galactosidase reviewed - GLB1 Inhibition '<' 50 %
Q9HCG7 BXGT020533 Non-lysosomal glucosylceramidase reviewed - GBA2 IC50 '=' 400000 nM
Q9SEH8 BXGT021581 alpha-1,2-Mannosidase unreviewed - Man1 Inhibition '<' 50 %
P35573 BXGT009850 Glycogen debranching enzyme reviewed Enzyme AGL IC50 '>' 100000 nM
Q9H227 BXGT020447 Cytosolic beta-glucosidase reviewed Enzyme GBA3 Inhibition '<' 50 %
P09848 BXGT006929 Lactase-phlorizin hydrolase reviewed Enzyme LCT IC50 '>' 1000000 nM
O00754 BXGT003944 Lysosomal alpha-mannosidase reviewed - MAN2B1 Inhibition '<' 50 %
Q9Y2E5 BXGT022231 Epididymis-specific alpha-mannosidase reviewed - MAN2B2 Inhibition '<' 50 %
D3ZUM4 BXGT002920 Beta-galactosidase unreviewed - Glb1 Inhibition '<' 50 %
Q2KIM0 BXGT014117 Tissue alpha-L-fucosidase reviewed - FUCA1 Inhibition '<' 50 %
O43451 BXGT004594 Maltase-glucoamylase, intestinal reviewed Enzyme MGAM Inhibition '<' 50 %
P04066 BXGT006142 Tissue alpha-L-fucosidase reviewed - FUCA1 Inhibition '<' 50 %
O00462 BXGT003925 Beta-mannosidase reviewed Enzyme MANBA Inhibition '<' 50 %
Q5DUH8 BXGT015324 Alpha-galactosidase unreviewed - gal1 Inhibition '<' 50 %
Q16739 BXGT013663 Ceramide glucosyltransferase reviewed Enzyme UGCG IC50 '=' 9000 nM
P14410 BXGT008009 Sucrase-isomaltase, intestinal reviewed Enzyme SI IC50 '=' 1000000 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF04454 Scorzoneroides autumnalis Scorzoneroides autumnalis Others
BXGF05329 Lactuca floridana Lactuca floridana Others
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease