Showing entry for Glycogen debranching enzyme


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009850
Protein NameGlycogen debranching enzyme
Uniport IdP35573
GeneAGL
Gene Id178
DomainGDE_C; hDGE_amylase; hGDE_central; hGDE_N
Pfam PF06202   PF14701   PF14702   PF14699  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.1 Carbohydrate metabolism hsa00500 Starch and sucrose metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0005978 glycogen biosynthetic process
Biological Process GO:0005980 glycogen catabolic process
Biological Process GO:0043312 neutrophil degranulation
Biological Process GO:0051384 response to glucocorticoid
Biological Process GO:0007584 response to nutrient
molecular function GO:0004134 4-alpha-glucanotransferase activity
molecular function GO:0004135 amylo-alpha-1,6-glucosidase activity
molecular function GO:0102500 beta-maltose 4-alpha-glucanotransferase activity
molecular function GO:0004133 glycogen debranching enzyme activity
molecular function GO:0030247 polysaccharide binding
molecular function GO:0031593 polyubiquitin modification-dependent protein binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005576 extracellular region
cellular component GO:1904813 ficolin-1-rich granule lumen
cellular component GO:0016234 inclusion body
cellular component GO:0043033 isoamylase complex
cellular component GO:0005634 nucleus
cellular component GO:0016529 sarcoplasmic reticulum
cellular component GO:0034774 secretory granule lumen
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-6798695 Neutrophil degranulation
R-HSA-70221 Glycogen breakdown (glycogenolysis)
R-HSA-71387 Metabolism of carbohydrates
R-HSA-8982491 Glycogen metabolism
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0017536 BXGD001114 Giardiasis Digestive System Diseases; Infections
C0017919 BXGD001150 Glycogen Storage Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0017921 BXGD001152 Glycogen storage disease type II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0017922 BXGD001153 Glycogen Storage Disease Type III Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0020473 BXGD001396 Hyperlipidemia Nutritional and Metabolic Diseases
C0020557 BXGD001432 Hypertriglyceridemia Nutritional and Metabolic Diseases
C0020615 BXGD001445 Hypoglycemia Nutritional and Metabolic Diseases
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0023487 BXGD001669 Acute Promyelocytic Leukemia Neoplasms
C0023787 BXGD001698 Lipodystrophy Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0026106 BXGD001889 Mild Mental Retardation Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0026848 BXGD001941 Myopathy Musculoskeletal Diseases; Nervous System Diseases
C0026850 BXGD001942 Muscular Dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0027055 BXGD001964 Myocardial Reperfusion Injury Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0030326 BXGD002209 Panniculitis Skin and Connective Tissue Diseases
C0030552 BXGD002238 Paresis Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0041948 BXGD002939 Uremia Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0151786 BXGD003475 Muscle Weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0220989 BXGD004353 Acquired partial lipodystrophy Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0221032 BXGD004374 Familial generalized lipodystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0241005 BXGD005072 Creatine phosphokinase serum increased
C0271694 BXGD006239 Familial partial lipodystrophy Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0340279 BXGD007314 Ventricular hypertrophy Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0349588 BXGD007933 Short stature
C0369183 BXGD007960 Erythrocyte Mean Corpuscular Hemoglobin Test
C0423224 BXGD008475 Sunken eyes Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0426429 BXGD008564 Broad nasal tip
C0578038 BXGD009542 Thin lips
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C1261502 BXGD011856 Finding of Mean Corpuscular Hemoglobin
C1836542 BXGD014129 Depressed nasal bridge
C1848701 BXGD014967 Elevated hepatic transaminase
C1848736 BXGD014970 Distal amyotrophy
C1853242 BXGD015322 Midface retrusion
C1858085 BXGD015770 Malar flattening
C1859592 BXGD015912 ATRICHIA WITH PAPULAR LESIONS Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C1865017 BXGD016283 Thin upper lip vermilion
C1866231 BXGD016388 Full cheeks
C1968739 BXGD016731 Glycogen Storage Disease IIIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C1968740 BXGD016732 Glycogen Storage Disease IIIB Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C1968741 BXGD016733 Glycogen Storage Disease IIIC Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C2919142 BXGD017867 Short Stature, CTCAE
C2936915 BXGD018152 Amylo-1,6-glucosidase deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C3695006 BXGD019341 GLYCOGEN STORAGE DISEASE, TYPE IIIb
C3695007 BXGD019342 GLYCOGEN STORAGE DISEASE, TYPE IIIa
C4316789 BXGD022698 Partial lipodystrophy Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0012694 Iminoribitol 133.07
BXGC0014605 2,5-Imino-2,5,6-Trideoxy-D-Manno-Heptitol 177.1
BXGC0032319 L-Ido-1-Deoxynojirimycin 163.08
BXGC0036355 1,4-Imino-1,2,4-Trideoxy-D-Arabinitol 117.08
BXGC0036823 1,4-Dideoxy-1,4-(Hydroxyethyliminiumyl)-D-Arabinitol 177.1
BXGC0041132 Duvoglustat 163.08
BXGC0041896 (2R,3R,4R)-2-(Hydroxymethyl)Pyrrolidine-3,4-Diol 133.07
BXGC0049001 1,4-dideoxy-1,4-imino-D-xylitol 133.07
BXGC0051203 2,5-Dideoxy-2,5-Imino-D-Mannitol 163.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein