Showing entry for (+)-Alpha-Tocopheryl Succinate


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0037274
Compound Name(+)-Alpha-Tocopheryl Succinate
Structure
FormulaC33H54O5
InchiKeyIELOKBJPULMYRW-NJQVLOCASA-N
SMILESC[C@@H](CCC[C@]1(C)CCc2c(O1)c(C)c(c(c2C)OC(=O)CCC(=O)O)C)CCC[C@@H](CCCC(C)C)C
InchiInChI=1S/C33H54O5/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-20-33(8)21-19-28-27(7)31(25(5)26(6)32(28)38-33)37-30(36)18-17-29(34)35/h22-24H,9-21H2,1-8H3,(H,34,35)/t23-,24-,33-/m1/s1
IUPAC4-oxo-4-[[(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl]oxy]butanoic acid
Molecular Weight530.4
Pubchem Id20353
Chembl IdCHEMBL81421
Targets of Information Source
DrugBank DB14001
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Q9UDX4 BXGT021669 SEC14-like protein 3 reviewed - SEC14L3 approved; nutraceutical; vet_approved -
O76054 BXGT005172 SEC14-like protein 2 reviewed - SEC14L2 approved; nutraceutical; vet_approved -
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 reviewed Nuclear receptor NR1I2 approved; nutraceutical; vet_approved -
P05771 BXGT006384 Protein kinase C beta type reviewed Kinase PRKCB approved; nutraceutical; vet_approved -
P09917 BXGT006941 Arachidonate 5-lipoxygenase reviewed Enzyme ALOX5 approved; nutraceutical; vet_approved -
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA approved; nutraceutical; vet_approved -
P23743 BXGT008902 Diacylglycerol kinase alpha reviewed Kinase DGKA approved; nutraceutical; vet_approved -
Q9Y6T7 BXGT022665 Diacylglycerol kinase beta reviewed Enzyme DGKB approved; nutraceutical; vet_approved -
Q16760 BXGT022666 Diacylglycerol kinase delta reviewed Enzyme DGKD approved; nutraceutical; vet_approved -
P52429 BXGT022667 Diacylglycerol kinase epsilon reviewed Enzyme DGKE approved; nutraceutical; vet_approved -
Q86XP1 BXGT022668 Diacylglycerol kinase eta reviewed Kinase DGKH approved; nutraceutical; vet_approved -
P49619 BXGT022669 Diacylglycerol kinase gamma reviewed Enzyme DGKG approved; nutraceutical; vet_approved -
O75912 BXGT022670 Diacylglycerol kinase iota reviewed Enzyme DGKI approved; nutraceutical; vet_approved -
Q5KSL6 BXGT022671 Diacylglycerol kinase kappa reviewed Enzyme DGKK approved; nutraceutical; vet_approved -
P52824 BXGT022672 Diacylglycerol kinase theta reviewed Kinase DGKQ approved; nutraceutical; vet_approved -
Q13574 BXGT013379 Diacylglycerol kinase zeta reviewed Enzyme DGKZ approved; nutraceutical; vet_approved -
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
CHEMBL CHEMBL81421
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
O94782 BXGT005332 Ubiquitin carboxyl-terminal hydrolase 1 reviewed Enzyme USP1 Potency - 35481 nM
P34152 BXGT009753 Focal adhesion kinase 1 reviewed - Ptk2 Activity - - -
P18031 BXGT008369 Tyrosine-protein phosphatase non-receptor type 1 reviewed - PTPN1 IC50 '=' 39010 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 29855 nM
P18031 BXGT008369 Tyrosine-protein phosphatase non-receptor type 1 reviewed - PTPN1 IC50 '=' 25050 nM
P18031 BXGT008369 Tyrosine-protein phosphatase non-receptor type 1 reviewed - PTPN1 IC50 '=' 45610 nM
P18031 BXGT008369 Tyrosine-protein phosphatase non-receptor type 1 reviewed - PTPN1 Inhibition - - -
P78417 BXGT011843 Glutathione S-transferase omega-1 reviewed - GSTO1 IC50 '=' 4000 nM
P18031 BXGT008369 Tyrosine-protein phosphatase non-receptor type 1 reviewed - PTPN1 IC50 '=' 20000 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00073 Japanese persimmon Diospyros kaki Fruits
BXGF00106 Mango Mangifera indica Fruits
BXGF02937 Senecio scandens Senecio scandens Medicinal Plant
BXGF05800 Mimosa pudica Mimosa pudica Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease