adisease

Showing entry for Carotid Stenosis

General Disease Information
BXGD Id	BXGD000458
Disease Name	Carotid Stenosis
Disease CUI Id	C0007282
MeSH Codes	C10 C14
Disease Class Name	Nervous System Diseases; Cardiovascular Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0001626
Human Phenotype Ontology Term	Abnormality of the cardiovascular system
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O15123	BXGT004130	Angiopoietin-2	285	reviewed	Signaling
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O75015	BXGT005095	Low affinity immunoglobulin gamma Fc region receptor III-B	2215	reviewed	Cell adhesion
O75173	BXGT005105	A disintegrin and metalloproteinase with thrombospondin motifs 4	9507	reviewed	Enzyme
O75844	BXGT005156	CAAX prenyl protease 1 homolog	10269	reviewed	Enzyme
O95477	BXGT005383	Phospholipid-transporting ATPase ABCA1	19	reviewed	Transporter
P00734	BXGT005630	Prothrombin	2147	reviewed	Enzyme
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01303	BXGT005748	Pro-neuropeptide Y	4852	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02795	BXGT005968	Metallothionein-2	4502	reviewed
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04070	BXGT006143	Vitamin K-dependent protein C	5624	reviewed	Enzyme
P04083	BXGT006147	Annexin A1	301	reviewed
P04275	BXGT006180	von Willebrand factor	7450	reviewed	Enzyme modulator
P05106	BXGT006315	Integrin beta-3	3690	reviewed	Receptor
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06858	BXGT006515	Lipoprotein lipase	4023	reviewed	Enzyme
P07204	BXGT006567	Thrombomodulin	7056	reviewed
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08254	BXGT006758	Stromelysin-1	4314	reviewed	Enzyme
P08637	BXGT006802	Low affinity immunoglobulin gamma Fc region receptor III-A	2214	reviewed	Cell adhesion
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P0DMV8	BXGT007509	Heat shock 70 kDa protein 1A	3304	reviewed
P0DMV9	BXGT007510	Heat shock 70 kDa protein 1B	3304	reviewed
P10909	BXGT007630	Clusterin	1191	reviewed
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P12104	BXGT007773	Fatty acid-binding protein, intestinal	2169	reviewed
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13726	BXGT007950	Tissue factor	2152	reviewed	Receptor
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P14921	BXGT008068	Protein C-ets-1	2113	reviewed	Transcription factor
P15090	BXGT008079	Fatty acid-binding protein, adipocyte	2167	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P19320	BXGT008470	Vascular cell adhesion protein 1	7412	reviewed
P27169	BXGT009161	Serum paraoxonase/arylesterase 1	5444	reviewed
P27708	BXGT009202	CAD protein	790	reviewed	Enzyme
P30536	BXGT009435	Translocator protein	706	reviewed
P33261	BXGT009707	Cytochrome P450 2C19	1557	reviewed
P39900	BXGT010148	Macrophage metalloelastase	4321	reviewed	Enzyme
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P47900	BXGT010595	P2Y purinoceptor 1	5028	reviewed	G-protein coupled receptor
P48023	BXGT010604	Tumor necrosis factor ligand superfamily member 6	356	reviewed	Signaling
P49585	BXGT010712	Choline-phosphate cytidylyltransferase A	5130	reviewed
P51681	BXGT010878	C-C chemokine receptor type 5	1234	reviewed	G-protein coupled receptor
P52788	BXGT010953	Spermine synthase	6611	reviewed
P54652	BXGT011064	Heat shock-related 70 kDa protein 2	3306	reviewed
P56945	BXGT011206	Breast cancer anti-estrogen resistance protein 1	9564	reviewed
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P62937	BXGT011471	Peptidyl-prolyl cis-trans isomerase A	5478	reviewed
P78325	BXGT011832	Disintegrin and metalloproteinase domain-containing protein 8	101	reviewed	Enzyme
P80188	BXGT011882	Neutrophil gelatinase-associated lipocalin	3934	reviewed	Enzyme
Q13093	BXGT013310	Platelet-activating factor acetylhydrolase	7941	reviewed	Enzyme
Q13231	BXGT013329	Chitotriosidase-1	1118	reviewed
Q13427	BXGT013354	Peptidyl-prolyl cis-trans isomerase G	9360	reviewed
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14676	BXGT013497	Mediator of DNA damage checkpoint protein 1	9656	reviewed
Q15389	BXGT013564	Angiopoietin-1	284	reviewed	Signaling
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q8NBP7	BXGT018541	Proprotein convertase subtilisin/kexin type 9	255738	reviewed	Enzyme
Q99538	BXGT019931	Legumain	5641	reviewed	Enzyme
Q9BYW2	BXGT020192	Histone-lysine N-methyltransferase SETD2	29072	reviewed	Epigenetic regulator
Q9NP99	BXGT021148	Triggering receptor expressed on myeloid cells 1	54210	reviewed
Q9P0K1	BXGT021288	Disintegrin and metalloproteinase domain-containing protein 22	53616	reviewed	Enzyme
Q9UM07	BXGT021771	Protein-arginine deiminase type-4	23569	reviewed
Q9UNN8	BXGT021791	Endothelial protein C receptor	10544	reviewed	Enzyme modulator
P00738	BXGT022874	Haptoglobin	3240	reviewed	Enzyme
O95140	BXGT024482	Mitofusin-2	9927	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}