Showing entry for Primary angle-closure glaucoma


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD001127
Disease NamePrimary angle-closure glaucoma
Disease CUI IdC0017606
MeSH Codes C11  
Disease Class NameEye Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0000478  
Human Phenotype Ontology TermAbnormality of the eye
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O15440 BXGT004170 Multidrug resistance-associated protein 5 10057 reviewed Transporter
O15527 BXGT004176 N-glycosylase/DNA lyase 4968 reviewed
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase 8654 reviewed
O95477 BXGT005383 Phospholipid-transporting ATPase ABCA1 19 reviewed Transporter
P00734 BXGT005630 Prothrombin 2147 reviewed Enzyme
P01024 BXGT005719 Complement C3 718 reviewed Enzyme modulator
P01034 BXGT005721 Cystatin-C 1471 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02452 BXGT005878 Collagen alpha-1(I) chain 1277 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P07339 BXGT006604 Cathepsin D 1509 reviewed Enzyme
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P09486 BXGT006897 SPARC 6678 reviewed Signaling
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P17516 BXGT008313 Aldo-keto reductase family 1 member C4 1109 reviewed Enzyme
P20813 BXGT008603 Cytochrome P450 2B6 1555 reviewed
P21589 BXGT008669 5'-nucleotidase 4907 reviewed Enzyme
P28300 BXGT009243 Protein-lysine 6-oxidase 4015 reviewed
P28329 BXGT009251 Choline O-acetyltransferase 1103 reviewed Enzyme
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P34130 BXGT009752 Neurotrophin-4 4909 reviewed Signaling
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P41214 BXGT010236 Eukaryotic translation initiation factor 2D 1939 reviewed Receptor
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P60953 BXGT011342 Cell division control protein 42 homolog 998 reviewed Enzyme modulator
P63000 BXGT011481 Ras-related C3 botulinum toxin substrate 1 5879 reviewed Enzyme modulator
Q16678 BXGT013656 Cytochrome P450 1B1 1545 reviewed Enzyme
Q70Z44 BXGT016686 5-hydroxytryptamine receptor 3D 200909 reviewed Ion channel
Q8WXA8 BXGT019008 5-hydroxytryptamine receptor 3C 170572 reviewed Ion channel
Q96AC1 BXGT019617 Fermitin family homolog 2 10979 reviewed
Q99972 BXGT019979 Myocilin 4653 reviewed Cellular structure
Q9NNW7 BXGT021139 Thioredoxin reductase 2, mitochondrial 10587 reviewed Enzyme
Q9Y4K0 BXGT022280 Lysyl oxidase homolog 2 4017 reviewed
P20036 BXGT022764 HLA class II histocompatibility antigen, DP alpha 1 chain 3113 reviewed Immune response
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease