Showing entry for Peutz-Jeghers Syndrome


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD002297
Disease NamePeutz-Jeghers Syndrome
Disease CUI IdC0031269
MeSH Codes C16   C06   C04   C17  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms; Skin and Connective Tissue Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00255 BXGT003903 Menin 4221 reviewed
O43683 BXGT004614 Mitotic checkpoint serine/threonine-protein kinase BUB1 699 reviewed Kinase
O43766 BXGT004622 Lipoyl synthase, mitochondrial 11019 reviewed
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 8856 reviewed Nuclear receptor
O96017 BXGT005415 Serine/threonine-protein kinase Chk2 11200 reviewed Kinase
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P07741 BXGT006666 Adenine phosphoribosyltransferase 353 reviewed
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P10644 BXGT007597 cAMP-dependent protein kinase type I-alpha regulatory subunit 5573 reviewed
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P11926 BXGT007760 Ornithine decarboxylase 4953 reviewed Enzyme
P20813 BXGT008603 Cytochrome P450 2B6 1555 reviewed
P25116 BXGT009025 Proteinase-activated receptor 1 2149 reviewed G-protein coupled receptor
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P40337 BXGT010174 von Hippel-Lindau disease tumor suppressor 7428 reviewed Enzyme
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P45985 BXGT010496 Dual specificity mitogen-activated protein kinase kinase 4 6416 reviewed Kinase
P51532 BXGT010852 Transcription activator BRG1 6597 reviewed Epigenetic regulator
P52701 BXGT010943 DNA mismatch repair protein Msh6 2956 reviewed Nucleic acid binding
P52952 BXGT010966 Homeobox protein Nkx-2.5 1482 reviewed Transcription factor
P54646 BXGT011062 5'-AMP-activated protein kinase catalytic subunit alpha-2 5563 reviewed Kinase
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P63092 BXGT011495 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short 2778 reviewed
Q01523 BXGT012594 Defensin-5 1670 reviewed
Q13131 BXGT013314 5'-AMP-activated protein kinase catalytic subunit alpha-1 5562 reviewed Kinase
Q13485 BXGT013363 Mothers against decapentaplegic homolog 4 4089 reviewed Transcription factor
Q15796 BXGT013599 Mothers against decapentaplegic homolog 2 4087 reviewed Transcription factor
Q15831 BXGT013604 Serine/threonine-protein kinase STK11 6794 reviewed Kinase
Q16543 BXGT013635 Hsp90 co-chaperone Cdc37 11140 reviewed Enzyme modulator
Q7RTN6 BXGT017085 STE20-related kinase adapter protein alpha 92335 reviewed Kinase
Q96L34 BXGT019689 MAP/microtubule affinity-regulating kinase 4 57787 reviewed Kinase
Q9HC98 BXGT020528 Serine/threonine-protein kinase Nek6 10783 reviewed Kinase
Q9P0L2 BXGT021289 Serine/threonine-protein kinase MARK1 4139 reviewed Kinase
Q9UIF7 BXGT021717 Adenine DNA glycosylase 4595 reviewed Enzyme
Q9Y376 BXGT022254 Calcium-binding protein 39 51719 reviewed Calcium-binding protein
Q9Y478 BXGT022271 5'-AMP-activated protein kinase subunit beta-1 5564 reviewed Kinase
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
P20809 BXGT025043 Interleukin-11 3589 reviewed
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease