Showing entry for STE20-related kinase adapter protein alpha


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT017085
Protein NameSTE20-related kinase adapter protein alpha
Uniport IdQ7RTN6
GeneSTRADA
Gene Id92335
DomainPkinase
Pfam PF00069  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04150 mTOR signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04152 AMPK signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0032147 activation of protein kinase activity
Biological Process GO:0007050 cell cycle arrest
Biological Process GO:0006611 protein export from nucleus
Biological Process GO:0006468 protein phosphorylation
molecular function GO:0005524 ATP binding
molecular function GO:0019900 kinase binding
molecular function GO:0030295 protein kinase activator activity
molecular function GO:0043539 protein serine/threonine kinase activator activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-165159 MTOR signalling
R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0005890 BXGD000345 Body Height
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0014772 BXGD000948 Red Blood Cell Count measurement
C0020224 BXGD001366 Polyhydramnios Female Urogenital Diseases and Pregnancy Complications
C0020534 BXGD001421 Orbital separation excessive Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0024433 BXGD001771 Macrostomia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0025149 BXGD001826 Medulloblastoma Neoplasms
C0026827 BXGD001936 Muscle hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027022 BXGD001962 Myeloproliferative disease Hemic and Lymphatic Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0031269 BXGD002297 Peutz-Jeghers Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms; Skin and Connective Tissue Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038379 BXGD002752 Strabismus Eye Diseases; Nervous System Diseases
C0151526 BXGD003432 Premature Birth Female Urogenital Diseases and Pregnancy Complications
C0205833 BXGD004130 Medullomyoblastoma Neoplasms
C0221355 BXGD004447 Macrocephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0232466 BXGD004543 Feeding difficulties
C0240309 BXGD005029 Hyperplasia of midface
C0240379 BXGD005033 Open mouth (finding)
C0278510 BXGD006526 Childhood Medulloblastoma Neoplasms
C0278876 BXGD006607 Adult Medulloblastoma Neoplasms
C0311394 BXGD006884 Difficulty walking Pathological Conditions, Signs and Symptoms
C0376532 BXGD008000 Epilepsy, Rolandic Nervous System Diseases
C0489786 BXGD009018 Height
C0557874 BXGD009444 Global developmental delay
C0751291 BXGD010379 Desmoplastic Medulloblastoma Neoplasms
C1096063 BXGD011600 Drug Resistant Epilepsy Nervous System Diseases
C1275668 BXGD012090 Melanotic medulloblastoma Neoplasms
C1531647 BXGD013301 Cerebral ventriculomegaly Nervous System Diseases
C1535926 BXGD013322 Neurodevelopmental Disorders Mental Disorders
C1836047 BXGD014074 Long face
C1839739 BXGD014400 Thick lower lip vermilion
C1839783 BXGD014407 Large forehead
C1845251 BXGD014734 Facial hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1846423 BXGD014812 Thick upper lip vermilion
C1849367 BXGD015046 Nasal bridge wide
C1850573 BXGD015154 Slender build Pathological Conditions, Signs and Symptoms
C1854882 BXGD015439 Absent speech Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1854919 BXGD015442 Severe psychomotor retardation
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1970203 BXGD016821 Polyhydramnios, Megalencephaly, And Symptomatic Epilepsy Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases; Nervous System Diseases; Behavior and Behavior Mechanisms
C3278923 BXGD018748 Dilated ventricles (finding)
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3887640 BXGD019908 Astrocytosis Pathological Conditions, Signs and Symptoms
C4505072 BXGD022953 Epileptic Syndromes Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0047692 Gefitinib 446.15
BXGC0050099 (2E,5S,6S,8Z,11S)-5,6,15-Trihydroxy-17-Methoxy-11-Methyl-12-Oxabicyclo[12.4.0]Octadeca-1(14),2,8,15,17-Pentaene-7,13-Dione 362.14
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein